Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
10 RAF1 related diseases 
hsa05034Alcoholism
hsa05152Tuberculosis
hsa05160Hepatitis C
hsa05164Influenza A
hsa05215Prostate cancer
hsa05218Melanoma
hsa05220Chronic myeloid leukemia
hsa05221Acute myeloid leukemia
611554LEOPARD syndrome 2
611553Noonan syndrome 5
Summary of query kinase
Query kinase ARAF (P10398), reference kinase: RAF1 (P04049)
Kinase group TKL
Number of conformation types 1 
Number of structural templates 1 (Total 345 inhibitors)
Number of RAF1 related diseases 10 (hsa05034 hsa05152 hsa05160 hsa05164 hsa05215 hsa05218 hsa05220 hsa05221 ...
Number of allelic variants 4 (L613V P261S S257L T491R
Select
Template
Comformation
Type 
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A 1 3OMVA_SM5
(RAF1)
TKL pyrazole bas... I 2 27 16