Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
2 ALK related diseases 
H00014Non-small cell lung cancer
613014{Neuroblastoma, susceptibility to, 3}
Summary of query kinase
Query kinase ROS1 (P08922), reference kinase: ALK (Q9UM73)
Kinase group TK
Number of conformation types 2 
Number of structural templates 5 (Total 242 inhibitors)
Number of ALK related diseases 2 (H00014 613014
Number of allelic variants 4 (G1128A R1192P R1275Q T1151M
Select
Template
Comformation
Type 
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A 1 2XBAA_571
(ALK)
TK 5-Amido-pyrr... I 17 55 50
B 4 3LCSA_STU
(ALK)
TK staurosporine I 73 100 109