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KIDFamMap
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
9 IRAK4 related diseases
hsa05133
Pertussis
hsa05140
Leishmaniasis
hsa05142
Chagas disease (American trypanosomiasis)
hsa05145
Toxoplasmosis
hsa05152
Tuberculosis
hsa05162
Measles
hsa05164
Influenza A
610799
Invasive pneumococcal disease, recurrent isolated, 1
607676
IRAK4 deficiency
Summary of query kinase
Query kinase
IRAK4 (
Q9NWZ3
)
Kinase group
TKL
Number of conformation types
1
Number of structural templates
2 (
Total 93 inhibitors
)
Number of IRAK4 related diseases
9 (
hsa05133
hsa05140
hsa05142
hsa05145
hsa05152
hsa05162
hsa05164
610799
...
)
Number of allelic variants
2 (
Q293X
R12C
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
2
2OIDA_ANP
(IRAK4)
TKL
Phosphoamino...
I
21
12
70
A
2OIDA_ANP
(IRAK4)
TKL
Phosphoamino...
I
21
12
70
21
12
70
A
2NRUA_T12
(IRAK4)
TKL
Kinome_2780
I
4
13
19
4
13
19