Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
13 JAK2 related diseases 
H00012Polycythemia vera
hsa05140Leishmaniasis
hsa05145Toxoplasmosis
hsa05152Tuberculosis
hsa05162Measles
hsa05164Influenza A
hsa05168Herpes simplex infection
600880{Budd-Chiari syndrome}
601626Leukemia, acute myelogenous
254450Myelofibrosis, idiopathic
OMIM
(147796)		Myeloproliferative disorder with erythrocytosis
263300Polycythemia vera
614521Thrombocythemia 3
Summary of query kinase
Query kinase JAK2 (O60674)
Kinase group TK
Number of conformation types 2 
Number of structural templates 14 (Total 612 inhibitors)
Number of JAK2 related diseases 13 (H00012 hsa05140 hsa05145 hsa05152 hsa05162 hsa05164 hsa05168 600880 ...) 
Number of allelic variants 4 (K539L K607N V617F V617I) 
Select
Template		 Comformation
Type 		 No. of
Templates		 Representative
Template		 Kinase
Group		 Representative
Inhibitor		 Inhibitor
Type		 No. of
Kinases		 No. of
Inhibitors		 No. of
Diseases
A 1 3JY9A_JZH
(JAK2)		 TK atropisomer 1 I 11 13 32
B 13 2B7AA_IZA
(JAK2)		 TK Pyridone 6 I 34 12 65