Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
6 ABL1 related diseases 
H00001Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)
H00004Chronic myeloid leukemia (CML)
hsa05130Pathogenic Escherichia coli infection
hsa05131Shigellosis
hsa05416Viral myocarditis
OMIM
(189980)
Leukemia, Philadelphia chromosome-positive, resistant to imatinib
Summary of query kinase
Query kinase ABL1 (P00519)
Kinase group TK
Number of conformation types 3 
Number of structural templates 18 (Total 660 inhibitors)
Number of ABL1 related diseases 6 (H00001 H00004 hsa05130 hsa05131 hsa05416 OMIM:189980
Number of allelic variants 6 (E255K E255V F311L M351T T315I Y253H
Select
Template
Comformation
Type 
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A 10 2HZ4A_4ST
(ABL1)
TK staurosporine I 159 103 156
E 7 3CS9A_NIL
(ABL1)
TK Nilotinib II 19 132 48
F 1 2HZ0A_GIN
(ABL1)
TK DB07970 II 6 67 20