Protein Surface  Ribbon
Inhibitor
  ATP Location
Pocket ATP NLP HAP CLP SP
8 INSR related diseases 
H00719Leprechaunism
H00942Rabson-Mendenhall syndrome
H01228Insulin-resistant diabetes mellitus with acanthosis nigricans (IRAN)
hsa04930Type II diabetes mellitus
610549Diabetes mellitus, insulin-resistant, with acanthosis nigricans
609968Hyperinsulinemic hypoglycemia, familial, 5
246200Leprechaunism
262190Rabson-Mendenhall syndrome
Summary of query kinase
Query kinase INSR (P06213)
Kinase group TK
Number of conformation types 3 
Number of structural templates 7 (Total 322 inhibitors)
Number of INSR related diseases 8 (H00719 H00942 H01228 hsa04930 610549 609968 246200 262190
Number of allelic variants 29 (A1134T A1135E E672X F382V G31R G366R G996V H209R I119M K121X ...
Select
Template
Comformation
Type 
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A 1 1IR3A_ANP
(INSR)
TK Phosphoamino... I 14 5 51
B 5 3EKNA_GS3
(INSR)
TK pyrrolo[2,3-... I 90 215 127
E 1 3ETAA_351
(INSR)
TK CP_724714 II 6 13 16