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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Summary of query kinase
Query kinase
MELK (
Q14680
)
Kinase group
CAMK
Number of conformation types
0
Number of structural templates
22 (
Total 68 inhibitors
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
4
2HZ4A_4ST
(ABL1)
CAMK
staurosporine
I
159
103
156
A
2HZ4A_4ST
(ABL1)
CAMK
staurosporine
I
159
103
156
159
103
156
A
2F4JA_VX6
(ABL1)
CAMK
VX-680
I
110
109
134
110
109
134
A
2XYNA_VX6
(ABL2)
CAMK
VX-680
I
79
101
105
79
101
105
A
1AGWA_SU2
(FGFR1)
CAMK
SU 4984
I
77
81
111
77
81
111
B
17
1OKYA_STU
(PDPK1)
CAMK
staurosporine
I
179
67
109
B
1OKYA_STU
(PDPK1)
CAMK
staurosporine
I
179
67
109
179
67
109
B
1OKZA_UCN
(PDPK1)
CAMK
UCN 02
I
179
60
109
179
60
109
B
2PE2A_464
(PDPK1)
CAMK
Indolinone b...
I
134
156
104
134
156
104
B
2XCKA_MH4
(PDPK1)
CAMK
MH4
I
46
431
75
46
431
75
B
3EFWA_AK8
(AURKA)
CAMK
3efw
I
100
59
105
100
59
105
B
3OTUA_BI4
(PDPK1)
CAMK
bisindolylma...
I
82
178
65
82
178
65
B
1UU7A_BI2
(PDPK1)
CAMK
bisindolylma...
I
82
178
65
82
178
65
B
1UU8A_BI1
(PDPK1)
CAMK
bisindolylma...
I
83
189
65
83
189
65
B
1UU9A_BI3
(PDPK1)
CAMK
3-[1-(3-AMIN...
I
83
180
69
83
180
69
B
1UVRA_BI8
(PDPK1)
CAMK
Ro 31-7549
I
82
181
65
82
181
65
B
3ORZA_BI4
(PDPK1)
CAMK
bisindolylma...
I
82
178
65
82
178
65
B
2BMCA_MPY
(AURKA)
CAMK
PHA-680632
I
107
108
107
107
108
107
B
3COHA_83H
(AURKA)
CAMK
AKI-001
I
79
88
65
79
88
65
B
1UU3A_LY4
(PDPK1)
CAMK
Ruboxistaurin
I
71
117
57
71
117
57
B
2PE0A_39Z
(PDPK1)
CAMK
2pe0
I
20
2
27
20
2
27
B
2B7AA_IZA
(JAK2)
CAMK
Pyridone 6
I
34
12
65
34
12
65
B
3MTLA_FEF
(PCTK1)
CAMK
indirubin de...
I
16
3
23
16
3
23
D
1
3AQVA_TAK
(PRKAA2)
CAMK
dorsomorphin
I
12
41
19
D
3AQVA_TAK
(PRKAA2)
CAMK
dorsomorphin
I
12
41
19
12
41
19