BioXGEM.
KIDFamMap
Home
Example1
Example2
Statistics
Document
Contact US
Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Summary of query kinase
Query kinase
NEK2 (
P51955
)
Kinase group
Other
Number of conformation types
2
Number of structural templates
17 (
Total 95 inhibitors
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
14
2JAVA_5Z5
(NEK2)
Other
pyrrollylact...
I
25
40
24
A
2JAVA_5Z5
(NEK2)
Other
pyrrollylact...
I
25
40
24
25
40
24
A
2XNOA_ED8
(NEK2)
Other
5-{6-[(1-Met...
I
12
82
9
12
82
9
A
2XNNA_430
(NEK2)
Other
Kinome_3463
I
12
83
9
12
83
9
A
2XNMA_WGZ
(NEK2)
Other
benzimidazol...
I
12
93
9
12
93
9
A
2XNPA_WCX
(NEK2)
Other
4-{5-[(1-Met...
I
12
34
17
12
34
17
A
2W5AA_ADP
(NEK2)
Other
Adenosine-5'...
I
6
5
8
6
5
8
A
2W5BA_SAP
(NEK2)
Other
adenosine te...
I
6
5
8
6
5
8
A
2XK8A_5R1
(NEK2)
Other
4-[3-Amino-6...
I
4
34
5
4
34
5
A
2XKDA_T3M
(NEK2)
Other
4-[3-Amino-6...
I
4
38
5
4
38
5
A
2XKCA_4VQ
(NEK2)
Other
4-[3-Amino-6...
I
4
39
5
4
39
5
A
2XK3A_XK3
(NEK2)
Other
XK3
I
2
8
0
2
8
0
A
2XK7A_30E
(NEK2)
Other
Erlotinib
I
2
26
1
2
26
1
A
2XK6A_EQH
(NEK2)
Other
XK3
I
2
8
0
2
8
0
A
2XKEA_WI2
(NEK2)
Other
1-[3-Amino-6...
I
2
21
1
2
21
1
B
3
2XK4A_OL2
(NEK2)
Other
4-[3-Amino-6...
I
8
44
12
B
2XK4A_OL2
(NEK2)
Other
4-[3-Amino-6...
I
8
44
12
8
44
12
B
2WQOA_VGK
(NEK2)
Other
4-[3-Amino-6...
I
8
51
12
8
51
12
B
2XKFA_BX1
(NEK2)
Other
1-[3-Amino-6...
I
4
30
8
4
30
8