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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Summary of query kinase
Query kinase
PAK2 (
Q13177
)
Kinase group
STE
Number of conformation types
0
Number of structural templates
27 (
Total 28 inhibitors
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
20
1Q3DA_STU
(GSK3B)
STE
staurosporine
I
115
71
61
A
1Q3DA_STU
(GSK3B)
STE
staurosporine
I
115
71
61
115
71
61
A
1AQ1A_STU
(CDK2)
STE
staurosporine
I
195
76
118
195
76
118
A
1QPDA_STU
(LCK)
STE
staurosporine
I
115
76
126
115
76
126
A
1NVQA_UCN
(CHEK1)
STE
UCN 02
I
179
65
79
179
65
79
A
1QPJA_STU
(LCK)
STE
staurosporine
I
115
76
126
115
76
126
A
3CKXA_STU
(STK24)
STE
staurosporine
I
176
104
141
176
104
141
A
1NVRA_STU
(CHEK1)
STE
staurosporine
I
179
71
79
179
71
79
A
1SM2A_STU
(ITK)
STE
staurosporine
I
99
104
128
99
104
128
A
1NXKA_STU
(MAPKAPK2)
STE
staurosporine
I
110
67
51
110
67
51
A
1SNUA_STU
(ITK)
STE
staurosporine
I
99
104
128
99
104
128
A
1YHSA_STU
(PIM1)
STE
staurosporine
I
78
64
50
78
64
50
A
1PKDA_UCN
(CDK2)
STE
UCN 02
I
195
67
118
195
67
118
A
2HY81_1ST
(PAK1)
STE
UCN 02
I
58
20
75
58
20
75
A
2WIHA_P48
(CDK2)
STE
VX_680
I
111
425
105
111
425
105
A
2IVUA_ZD6
(RET)
STE
Vandetanib
I
83
291
121
83
291
121
A
2IW6A_QQ2
(CDK2)
STE
2iw6
I
112
209
86
112
209
86
A
1AGWA_SU2
(FGFR1)
STE
SU 4984
I
77
81
111
77
81
111
A
1NVSA_UCM
(CHEK1)
STE
SB218078
I
97
6
53
97
6
53
A
1Q3WA_ATU
(GSK3B)
STE
alsterpaullone
I
24
28
19
24
28
19
A
3IKAA_0UN
(EGFR)
STE
2jkk
I
76
120
108
76
120
108
B
7
3CBLA_STU
(FES)
STE
staurosporine
I
131
107
138
B
3CBLA_STU
(FES)
STE
staurosporine
I
131
107
138
131
107
138
B
3CD3A_STU
(FES)
STE
staurosporine
I
131
107
138
131
107
138
B
1OKYA_STU
(PDPK1)
STE
staurosporine
I
179
67
109
179
67
109
B
1OKZA_UCN
(PDPK1)
STE
UCN 02
I
179
60
109
179
60
109
B
3BKBA_STU
(FES)
STE
staurosporine
I
131
107
138
131
107
138
B
1H07A_MFP
(CDK2)
STE
AC1NAKJQ
I
90
241
80
90
241
80
B
2PE2A_464
(PDPK1)
STE
Indolinone b...
I
134
156
104
134
156
104