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KIDFamMap
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Example2
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
2 PTK2 related diseases
hsa05146
Amoebiasis
hsa05222
Small cell lung cancer
Summary of query kinase
Query kinase
PTK2 (
Q05397
)
Kinase group
TK
Number of conformation types
2
Number of structural templates
4 (
Total 307 inhibitors
)
Number of PTK2 related diseases
2 (
hsa05146
hsa05222
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
1
2ETMA_7PY
(PTK2)
TK
DB07248
I
10
101
25
A
2ETMA_7PY
(PTK2)
TK
DB07248
I
10
101
25
10
101
25
B
3
1MP8A_ADP
(PTK2)
TK
Adenosine-5'...
I
16
11
50
B
1MP8A_ADP
(PTK2)
TK
Adenosine-5'...
I
16
11
50
16
11
50
B
2IJMA_ATP
(PTK2)
TK
Adenosine-5'...
I
16
11
50
16
11
50
B
3BZ3A_YAM
(PTK2)
TK
PF-562271
I
2
13
2
2
13
2