KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1U59A_STU (PDB code: 1U59, chain A)
Number of involved diseases in the family	114

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	CDK2, CHEK2, CHUK, EGFR, EPHB2, FGFR1, FGFR2, IGF1R, INSRR, MAP2K1, RAF1	46	Link
n/a	Epstein-Barr virus infection	CDK2, CHUK, EIF2AK2, FGR, JAK1, JAK3, LYN, MAP2K7, SYK	19	Link
	Leukemia	ABL1, ABL2, CHUK, JAK2, MAP2K1, RAF1, RPS6KB1, RPS6KB2	13	Link
n/a	Measles	CDK2, CHUK, EIF2AK2, FYN, JAK1, JAK2, JAK3, PRKCQ	19	Link
n/a	Influenza A	EIF2AK2, JAK1, JAK2, MAP2K1, MAP2K7, PRKCA, RAF1	60	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CHUK, CSK, EGFR, LYN, MET, SRC	41	Link
	Melanoma	EGFR, FGFR1, IGF1R, MAP2K1, MET, RAF1	41	Link
	Lung cancer	ALK, CDK2, CHUK, EGFR, PTK2, ROS1	43	Link
n/a	Herpes simplex infection	CDK2, CHUK, EIF2AK2, JAK1, JAK2	15	Link
n/a	Tuberculosis	JAK1, JAK2, RAF1, SRC, SYK	21	Link
n/a	Hepatitis C	CHUK, EGFR, EIF2AK2, JAK1, RAF1	41	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	16	Link
n/a	Bladder cancer	DAPK1, EGFR, FGFR3	39	Link
n/a	Alcoholism	MAP2K1, NTRK2, RAF1	11	Link
n/a	Toxoplasmosis	CHUK, JAK1, JAK2	10	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA	61	Link
	Gastric cancer	EGFR, FGFR2, MET	39	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	13	Link
n/a	Immunodeficiencies	JAK3, LCK, ZAP70	16	Link
n/a	Shigellosis	ABL1, CHUK, SRC	20	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	SCID	JAK3, LCK	16	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
n/a	Choriocarcinoma	CSF1R, EGFR	43	Link
n/a	Prion diseases	FYN, MAP2K1	11	Link
n/a	Leishmaniasis	JAK1, JAK2	10	Link
n/a	Thyroid cancer	NTRK1, RET	18	Link
	Diabetes mellitus	INSR, PRKCD	15	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
	Colon cancer	AURKA, SRC	19	Link
n/a	Amoebiasis	PRKCA, PTK2	57	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	18	Link
n/a	Cervical cancer	EGFR, FGFR3	38	Link
n/a	Salmonella infection	PKN1, PKN2	11	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
	Apert syndrome	FGFR2	8	Link
	Trigonocephaly	FGFR1	9	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
	Craniosynostosis	FGFR2	8	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
	Kallmann syndrome	FGFR1	9	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
n/a	Oral cancer	EGFR	38	Link
	Adenocarcinoma of lung	EGFR	38	Link
	Li-Fraumeni syndrome	CHEK2	5	Link
	Breast cancer	CHEK2	5	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
	Agammaglobulinemia	BTK	5	Link
n/a	Agammaglobulinemias	BTK	5	Link
n/a	Pituitary Dwarfism	BTK	5	Link
	Osteosarcoma	CHEK2	5	Link
n/a	Chagas disease	CHUK	6	Link
n/a	Glioma	EGFR	38	Link
n/a	Laryngeal cancer	EGFR	38	Link
n/a	Esophageal cancer	EGFR	38	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
n/a	Cocoon syndrome	CHUK	6	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	13	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	3	Link
n/a	Achondroplasia	FGFR3	7	Link
	Scaphocephaly	FGFR2	8	Link
n/a	Obesity	NTRK2	9	Link
n/a	Vibrio cholerae infection	PRKCA	55	Link
n/a	African trypanosomiasis	PRKCA	55	Link
n/a	Pituitary tumor	PRKCA	55	Link
n/a	Insensitivity to pain	NTRK1	15	Link
n/a	Myasthenic syndrome	MUSK	5	Link
n/a	Cholangiocarcinoma	MET	8	Link
n/a	Malaria	MET	8	Link
n/a	Autism suseptibility	MET	8	Link
n/a	Congenital myasthenic syndrome	MUSK	5	Link
	Hepatocellular carcinoma	MET	8	Link
n/a	Type I diabetes mellitus	PRKCQ	8	Link
	LEOPARD syndrome	RAF1	2	Link
	Renal agenesis	RET	11	Link
n/a	Basal cell carcinoma	STK36	3	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
	Selective T-cell defect	ZAP70	10	Link
	Pheochromocytoma	RET	11	Link
	Multiple endocrine neoplasia	RET	11	Link
	Noonan syndrome	RAF1	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	11	Link
	Hirschsprung disease	RET	11	Link
	Central hypoventilation syndrome	RET	11	Link
n/a	Congenital central hypoventilation syndrome	RET	11	Link
	Renal cell carcinoma	MET	8	Link
	Cardiofaciocutaneous syndrome	MAP2K1	4	Link
n/a	Nevus	FGFR3	7	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
	Colorectal cancer	FGFR3	7	Link
n/a	CATSHL syndrome	FGFR3	7	Link
n/a	Malignant pleural mesothelioma	IGF1R	5	Link
n/a	Synovial sarcoma	IGF1R	5	Link
	Myelofibrosis	JAK2	10	Link
n/a	Myeloproliferative disorder	JAK2	10	Link
	Thrombocythemia	JAK2	10	Link
n/a	Noonan syndrome and related disorders	MAP2K1	4	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
	Polycythemia vera	JAK2	10	Link
	Insulin-like growth factor I	IGF1R	5	Link
n/a	Leprechaunism	INSR	5	Link
	Rabson-Mendenhall syndrome	INSR	5	Link
	Lymphoproliferative syndrome	ITK	6	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link

BioXGEM.

KIDFamMap

Allelic Variants