KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2DQ7X_STU (PDB code: 2DQ7, chain X)
Number of involved diseases in the family	124

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	CDK2, EGFR, EPHB2, ERBB2, FGFR1, FGFR2, MAPK1, PDGFRA, PDGFRB	45	Link
n/a	Epstein-Barr virus infection	CDK2, FGR, JAK1, JAK3, LYN, MAPK14, SYK, TYK2	19	Link
n/a	Measles	CDK2, FYN, IRAK4, JAK1, JAK2, JAK3, PRKCQ, TYK2	18	Link
n/a	Tuberculosis	IRAK4, JAK1, JAK2, MAPK1, MAPK14, SRC, SYK	21	Link
	Leukemia	ABL1, ABL2, JAK2, KIT, MAPK1, PDGFRB, TGFBR1	15	Link
n/a	Influenza A	IRAK4, JAK1, JAK2, MAPK1, MAPK14, PRKCA, TYK2	60	Link
n/a	Toxoplasmosis	IRAK4, JAK1, JAK2, MAPK1, MAPK14, TYK2	12	Link
	Melanoma	EGFR, FGFR1, MAPK1, PDGFRA, PDGFRB	42	Link
n/a	Hepatitis C	EGFR, JAK1, MAPK1, MAPK14, TYK2	41	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, LYN, MAPK14, SRC	41	Link
n/a	Leishmaniasis	IRAK4, JAK1, JAK2, MAPK1, MAPK14	12	Link
n/a	Salmonella infection	MAPK1, MAPK14, PKN1, PKN2	13	Link
n/a	Chagas disease	IRAK4, MAPK1, MAPK14, TGFBR1	6	Link
n/a	Herpes simplex infection	CDK2, JAK1, JAK2, TYK2	14	Link
n/a	Shigellosis	ABL1, MAPK1, MAPK14, SRC	20	Link
	Lung cancer	ALK, CDK2, EGFR, ROS1	43	Link
	Diabetes mellitus	INSR, MAPK1, PRKCD, PRKCE	15	Link
n/a	Bladder cancer	EGFR, ERBB2, FGFR3	38	Link
	Gastric cancer	EGFR, ERBB2, FGFR2	39	Link
n/a	Pertussis	IRAK4, MAPK1, MAPK14	6	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	13	Link
n/a	Choriocarcinoma	CSF1R, EGFR, ERBB2	43	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA	61	Link
n/a	Glioma	EGFR, PDGFRA, PDGFRB	41	Link
n/a	Immunodeficiencies	JAK3, LCK, ZAP70	16	Link
n/a	Cervical cancer	EGFR, ERBB2, FGFR3	38	Link
	Neuroblastoma	ALK, NTRK2, NTRK3	10	Link
	Adenocarcinoma of lung	EGFR, ERBB2	38	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	12	Link
n/a	Prion diseases	FYN, MAPK1	11	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
	SCID	JAK3, LCK	16	Link
n/a	Pancreatic cancer	ACVR1B, ERBB2	3	Link
n/a	Alcoholism	MAPK1, NTRK2	11	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	12	Link
n/a	Juvenile polyposis syndrome	BMPR1A	2	Link
	Kallmann syndrome	FGFR1	9	Link
	Brachydactyly	BMPR1B	1	Link
n/a	Polyposis	BMPR1A	2	Link
	Trigonocephaly	FGFR1	9	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
	Apert syndrome	FGFR2	8	Link
	Craniosynostosis	FGFR2	8	Link
	Fibrodysplasia ossificans progressiva	ACVR1	3	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
	Ovarian cancer	ERBB2	2	Link
	Breast cancer	ERBB2	2	Link
	Endometrial Cancer	ERBB2	2	Link
n/a	Oral cancer	EGFR	38	Link
n/a	Laryngeal cancer	EGFR	38	Link
n/a	Esophageal cancer	EGFR	38	Link
n/a	Cholangiocarcinoma	ERBB2	2	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	13	Link
	Glioblastoma	ERBB2	2	Link
n/a	Chrondrodysplasia	BMPR1B	1	Link
n/a	Agammaglobulinemias	BTK	5	Link
n/a	Pituitary Dwarfism	BTK	5	Link
n/a	Cocaine addiction	CDK5	5	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
	Agammaglobulinemia	BTK	5	Link
	Colorectal cancer	FGFR3	7	Link
	Scaphocephaly	FGFR2	8	Link
n/a	Pituitary tumor	PRKCA	55	Link
n/a	Type I diabetes mellitus	PRKCQ	8	Link
n/a	Thyroid cancer	RET	11	Link
n/a	Renal agenesis and Renal adysplasia	RET	11	Link
n/a	Amoebiasis	PRKCA	55	Link
n/a	African trypanosomiasis	PRKCA	55	Link
n/a	Congenital myasthenic syndrome	MUSK	5	Link
n/a	Myasthenic syndrome	MUSK	5	Link
n/a	Obesity	NTRK2	9	Link
n/a	Vibrio cholerae infection	PRKCA	55	Link
n/a	Hypereosinophilic syndrome	PDGFRA	10	Link
	Hirschsprung disease	RET	11	Link
n/a	Congenital central hypoventilation syndrome	RET	11	Link
	Loeys-Dietz syndrome	TGFBR1	2	Link
n/a	Familial thoracic aortic aneurysm and dissection	TGFBR1	2	Link
	Multiple self-healing squamous epithelioma	TGFBR1	2	Link
	Selective T-cell defect	ZAP70	10	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	8	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
	Colon cancer	SRC	19	Link
	Central hypoventilation syndrome	RET	11	Link
n/a	Medullary thyroid carcinoma	RET	11	Link
	Multiple endocrine neoplasia	RET	11	Link
	Renal agenesis	RET	11	Link
	Pheochromocytoma	RET	11	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	1	Link
	REtinitis pigmentosa	MAK	1	Link
n/a	Nevus	FGFR3	7	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	Achondroplasia	FGFR3	7	Link
n/a	CATSHL syndrome	FGFR3	7	Link
n/a	Leprechaunism	INSR	5	Link
	Rabson-Mendenhall syndrome	INSR	5	Link
	Thrombocythemia	JAK2	10	Link
	Piebaldism	KIT	12	Link
n/a	Germ cell tumors	KIT	12	Link
	Mastocytosis with associated hematologic disorder	KIT	12	Link
	Mast cell leukemia	KIT	12	Link
	Myelofibrosis	JAK2	10	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link
n/a	Invasive pneumococcal disease	IRAK4	4	Link
	IRAK4 deficiency	IRAK4	4	Link
	Polycythemia vera	JAK2	10	Link
	Lymphoproliferative syndrome	ITK	6	Link

BioXGEM.

KIDFamMap

Allelic Variants