Allelic Variants

There are no related allelic variants
Related diseases of KIF 2HZ4A_4ST (PDB code: 2HZ4, chain A)
Number of involved diseases in the family 156
Allelic
Variants		 Disease Description Involved kinases
(This family)		 Inhibitor of
Involved Kinases		 Search
Disease
n/aEpstein-Barr virus infectionCDC2, CDK2, FGR, JAK1, JAK3,
LYN, MAP3K7, MAPK14, PRKACA,
PRKACB, PRKACG, PRKX, SYK,
TYK2		17Link
Prostate cancerCDK2, EGFR, EPHB2, ERBB2,
FGFR1, FGFR2, IGF1R, INSRR,
MAP2K1, PDGFRA, PDGFRB,
PDPK1		44Link
n/aMeaslesCDK2, CDK6, FYN, IRAK4,
JAK1, JAK2, JAK3, MAP3K7,
PRKCQ, TYK2		16Link
LeukemiaABL1, ABL2, CDK6, JAK2, KIT,
MAP2K1, PDGFRB, RPS6KB1,
TGFBR1		16Link
n/aInfluenza AIRAK4, JAK1, JAK2, MAP2K1,
MAPK14, PRKCA, PRKCB, TYK2		59Link
MelanomaCDK6, EGFR, FGFR1, IGF1R,
MAP2K1, MET, PDGFRA, PDGFRB		42Link
n/aTuberculosisIRAK4, JAK1, JAK2, MAPK14,
PLK3, RIPK2, SRC, SYK		20Link
n/aVibrio cholerae infectionPRKACA, PRKACB, PRKACG,
PRKCA, PRKCB, PRKX		57Link
n/aCardiomyopathyPRKAA1, PRKAA2, PRKACA,
PRKACB, PRKACG, PRKX		9Link
n/aLeishmaniasisIRAK4, JAK1, JAK2, MAP3K7,
MAPK14, PRKCB		15Link
n/aToxoplasmosisIRAK4, JAK1, JAK2, MAP3K7,
MAPK14, TYK2		12Link
n/aHerpes simplex infectionCDC2, CDK2, JAK1, JAK2,
MAP3K7, TYK2		14Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCSK, EGFR, LYN, MAPK14, MET,
SRC		40Link
n/aAmoebiasisPRKACA, PRKACB, PRKACG,
PRKCA, PRKCB, PRKX		57Link
n/aPrion diseasesFYN, MAP2K1, PRKACA, PRKACB,
PRKACG, PRKX		11Link
Lung cancerALK, CDK2, CDK6, EGFR, ROS142Link
n/aCocaine addictionCDK5, PRKACA, PRKACB,
PRKACG, PRKX		9Link
n/aBladder cancerDAPK1, EGFR, ERBB2, FGFR338Link
Gastric cancerEGFR, ERBB2, FGFR2, MET38Link
NeuroblastomaALK, NTRK1, NTRK2, NTRK314Link
n/aHepatitis CEGFR, JAK1, MAPK14, TYK240Link
n/aShigellosisABL1, MAPK14, RIPK2, SRC19Link
Diabetes mellitusINSR, PRKCD, PRKCE14Link
n/aChoriocarcinomaCSF1R, EGFR, ERBB239Link
n/aSalmonella infectionMAPK14, PKN1, PKN212Link
n/aAlcoholismMAP2K1, NTRK2, PRKACA11Link
n/aChagas diseaseIRAK4, MAPK14, TGFBR15Link
n/aCervical cancerEGFR, ERBB2, FGFR337Link
n/aImmunodeficienciesJAK3, LCK, ZAP7014Link
n/aPathogenic Escherichia coli infectionABL1, FYN, PRKCA60Link
n/aGliomaEGFR, PDGFRA, PDGFRB40Link
n/aViral myocarditisABL1, ABL2, FYN13Link
n/aMyeloproliferative disorderJAK2, PDGFRB12Link
SCIDJAK3, LCK14Link
Adenocarcinoma of lungEGFR, ERBB237Link
Gastrointestinal stromal tumorKIT, PDGFRA12Link
n/aCholangiocarcinomaERBB2, MET8Link
n/aPertussisIRAK4, MAPK145Link
Jackson-Weiss syndromeFGFR1, FGFR29Link
n/aThyroid cancerNTRK1, RET14Link
Crouzon syndromeFGFR2, FGFR38Link
LADD syndromeFGFR2, FGFR38Link
n/aAfrican trypanosomiasisPRKCA, PRKCB54Link
n/aPancreatic cancerACVR1B, ERBB23Link
Colon cancerAURKA, SRC18Link
n/aMedullary thyroid carcinomaNTRK1, RET14Link
HemangiomaFLT4, KDR46Link
Pfeiffer syndromeFGFR1, FGFR29Link
ScaphocephalyFGFR28Link
Breast cancerERBB22Link
TrigonocephalyFGFR19Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR28Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR28Link
Ovarian cancerERBB22Link
n/aSaethre-Chotzen syndromeFGFR28Link
Osteoglophonic dysplasiaFGFR19Link
GlioblastomaERBB22Link
Bent bone dysplasia syndromeFGFR28Link
Beare-Stevenson cutis gyrata syndromeFGFR28Link
Hypogonadotropic hypogonadismFGFR19Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR28Link
Apert syndromeFGFR28Link
CraniosynostosisFGFR28Link
Kallmann syndromeFGFR19Link
n/aOral cancerEGFR37Link
Endometrial CancerERBB22Link
n/aPituitary DwarfismBTK5Link
AgammaglobulinemiaBTK5Link
n/aAgammaglobulinemia and isolated hormone deficiencyBTK5Link
Selective T-cell defectZAP7010Link
n/aAgammaglobulinemiasBTK5Link
n/aChrondrodysplasiaBMPR1B1Link
Fibrodysplasia ossificans progressivaACVR13Link
n/aMaturity onset diabetes of the youngBLK8Link
n/aJuvenile polyposis syndromeBMPR1A2Link
BrachydactylyBMPR1B1Link
n/aPolyposisBMPR1A2Link
n/aTyrosine kinase 2 deficiencyTYK28Link
Multiple self-healing squamous epitheliomaTGFBR12Link
n/aRheumatoid arthritisTEK32Link
n/aSpondylometaepiphyseal dysplasiaDDR23Link
n/aMultiple myelomaFGFR37Link
n/aLaryngeal cancerEGFR37Link
n/aEsophageal cancerEGFR37Link
n/aLeukoencephalopathy, diffuse hereditary, with spheroidsCSF1R10Link
n/aEpileptic encephalopathyCDKL51Link
n/aFamilial thoracic aortic aneurysm and dissectionTGFBR12Link
Loeys-Dietz syndromeTGFBR12Link
n/aPrader-Willi and Angelman syndromesCDKL51Link
n/aAngelman syndrome-likeCDKL51Link
n/aEarly infantile epileptic encephalopathyCDKL51Link
n/aNevusFGFR37Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR37Link
n/aCongenital myasthenic syndromeMUSK5Link
Hepatocellular carcinomaMET8Link
n/aMyasthenic syndromeMUSK5Link
n/aDeafness, autosomal recessiveMYO3A2Link
n/aShort rib-polydactyly syndormeNEK13Link
DeafnessMYO3A2Link
n/aAutism suseptibilityMET8Link
n/aMalariaMET8Link
REtinitis pigmentosaMAK1Link
Mastocytosis with associated hematologic disorderKIT12Link
n/aNoonan syndrome and related disordersMAP2K14Link
Cardiofaciocutaneous syndromeMAP2K14Link
Renal cell carcinomaMET8Link
n/aAmyotrophic lateral sclerosisMAPK141Link
n/aNephronophthisis-medullary cystic kidney diseaseNEK81Link
n/aNephronophthisisNEK81Link
n/aRenal agenesis and Renal adysplasiaRET9Link
n/aType I diabetes mellitusPRKCQ8Link
Hirschsprung diseaseRET9Link
n/aCongenital central hypoventilation syndromeRET9Link
Multiple endocrine neoplasiaRET9Link
Central hypoventilation syndromeRET9Link
n/aCerebral infarctionPRKCH11Link
n/aPituitary tumorPRKCA54Link
n/aObesityNTRK29Link
n/aInsensitivity to painNTRK113Link
n/aHypereosinophilic syndromePDGFRA10Link
n/aNon-syndromic X-linked mental retardationRPS6KA38Link
Renal agenesisRET9Link
n/aPopliteal pterygium syndromeRIPK41Link
Mast cell leukemiaKIT12Link
n/aGerm cell tumorsKIT12Link
n/aLymphedemasFLT412Link
n/aCancer progression/metastasisFGFR43Link
n/aLymphedemaFLT412Link
Venous malformationsTEK32Link
n/aMalignant pleural mesotheliomaIGF1R4Link
n/aEndocrine-cerebroosteodysplasiaICK2Link
n/aThanatophoric dysplasiaFGFR37Link
n/aSpermatocytic seminomaFGFR37Link
n/aAchondroplasiaFGFR37Link
n/aCATSHL syndromeFGFR37Link
Colorectal cancerFGFR37Link
n/aHypochondroplasiaFGFR37Link
PheochromocytomaRET9Link
n/aMuenke syndromeFGFR37Link
n/aSynovial sarcomaIGF1R4Link
Insulin-like growth factor IIGF1R4Link
Polycythemia veraJAK210Link
Lymphoproliferative syndromeITK6Link
n/aBudd-Chiari syndromeJAK210Link
MyelofibrosisJAK210Link
PiebaldismKIT12Link
ThrombocythemiaJAK210Link
IRAK4 deficiencyIRAK44Link
n/aInvasive pneumococcal diseaseIRAK44Link
Rabson-Mendenhall syndromeINSR5Link
n/aLeprechaunismINSR5Link
Hyperinsulinemic hypoglycemiaINSR5Link
n/aTransient erythroblastopenia of childhoodTEC2Link
n/aCoffin-Lowry syndromeRPS6KA38Link
Mental retardationRPS6KA38Link
n/aBasal cell carcinomaSTK363Link