KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2HZIA_JIN (PDB code: 2HZI, chain A)
Number of involved diseases in the family	120
Number of ABL1 related diseases	4

All kinase in this family ABL1

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	CDC2, CDK2, FGR, JAK1, JAK3, LYN, MAPK14, RIPK1, SYK, TYK2	18	Link
	Prostate cancer	BRAF, CDK2, EGFR, EPHB2, FGFR1, FGFR2, MAP2K1, PDGFRA, PDGFRB	54	Link
	Leukemia	ABL1, ABL2, BRAF, JAK2, KIT, MAP2K1, PDGFRB, TGFBR1	62	Link
n/a	Tuberculosis	JAK1, JAK2, MAPK14, PLK3, RIPK2, SRC, SYK	61	Link
	Melanoma	BRAF, EGFR, FGFR1, MAP2K1, MET, PDGFRA, PDGFRB	52	Link
n/a	Measles	CDK2, FYN, JAK1, JAK2, JAK3, TYK2	3	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, LYN, MAPK14, MET, SRC	62	Link
n/a	Hepatitis C	BRAF, EGFR, JAK1, MAPK14, RIPK1, TYK2	37	Link
n/a	Herpes simplex infection	CDC2, CDK2, JAK1, JAK2, TYK2	3	Link
n/a	Influenza A	JAK1, JAK2, MAP2K1, MAPK14, TYK2	16	Link
n/a	Shigellosis	ABL1, MAPK14, RIPK2, SRC	64	Link
n/a	Toxoplasmosis	JAK1, JAK2, MAPK14, TYK2	16	Link
	Lung cancer	BRAF, CDK2, EGFR	28	Link
	Gastric cancer	EGFR, FGFR2, MET	26	Link
n/a	Leishmaniasis	JAK1, JAK2, MAPK14	16	Link
n/a	Glioma	EGFR, PDGFRA, PDGFRB	51	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	19	Link
n/a	Immunodeficiencies	JAK3, LCK	13	Link
	SCID	JAK3, LCK	13	Link
n/a	Chagas disease	MAPK14, TGFBR1	16	Link
n/a	Choriocarcinoma	CSF1R, EGFR	27	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	9	Link
n/a	Cervical cancer	EGFR, FGFR3	27	Link
n/a	Bladder cancer	EGFR, FGFR3	27	Link
	Colorectal cancer	BRAF, FGFR3	5	Link
	Hemangioma	FLT4, KDR	3	Link
	Pfeiffer syndrome	FGFR1, FGFR2	50	Link
	LADD syndrome	FGFR2, FGFR3	5	Link
	Crouzon syndrome	FGFR2, FGFR3	5	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN	19	Link
n/a	Prion diseases	FYN, MAP2K1	1	Link
n/a	Thyroid cancer	BRAF, RET	1	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	50	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	48	Link
	Cardiofaciocutaneous syndrome	BRAF, MAP2K1	1	Link
	Adenocarcinoma of lung	BRAF, EGFR	26	Link
n/a	Noonan syndrome and related disorders	BRAF, MAP2K1	1	Link
n/a	Alcoholism	BRAF, MAP2K1	1	Link
	Hypogonadotropic hypogonadism	FGFR1	50	Link
n/a	Laryngeal cancer	EGFR	26	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	1	Link
	Apert syndrome	FGFR2	1	Link
	Kallmann syndrome	FGFR1	50	Link
	Trigonocephaly	FGFR1	50	Link
n/a	Type I diabetes mellitus	ERBB3	1	Link
n/a	Lethal congenital contractural syndrome	ERBB3	1	Link
	Osteoglophonic dysplasia	FGFR1	50	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	2	Link
n/a	Esophageal cancer	EGFR	26	Link
	Brachydactyly	BMPR1B	1	Link
n/a	Chrondrodysplasia	BMPR1B	1	Link
n/a	Polyposis	BMPR1A	1	Link
n/a	Juvenile polyposis syndrome	BMPR1A	1	Link
	Fibrodysplasia ossificans progressiva	ACVR1	1	Link
n/a	Pancreatic cancer	ACVR1B	1	Link
n/a	Maturity onset diabetes of the young	BLK	1	Link
n/a	Malignant melanoma	BRAF	1	Link
	LEOPARD syndrome	BRAF	1	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	1	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	1	Link
n/a	Oral cancer	EGFR	26	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	1	Link
	Agammaglobulinemia	BTK	1	Link
	Noonan syndrome	BRAF	1	Link
n/a	Agammaglobulinemias	BTK	1	Link
n/a	Pituitary Dwarfism	BTK	1	Link
	Scaphocephaly	FGFR2	1	Link
	Bent bone dysplasia syndrome	FGFR2	1	Link
n/a	Hypereosinophilic syndrome	PDGFRA	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	1	Link
	Hirschsprung disease	RET	1	Link
n/a	Congenital central hypoventilation syndrome	RET	1	Link
	Neuroblastoma	NTRK3	1	Link
n/a	Short rib-polydactyly syndorme	NEK1	1	Link
	Renal cell carcinoma	MET	1	Link
n/a	Cholangiocarcinoma	MET	1	Link
n/a	Malaria	MET	1	Link
	Hepatocellular carcinoma	MET	1	Link
n/a	Autism suseptibility	MET	1	Link
	Central hypoventilation syndrome	RET	1	Link
n/a	Medullary thyroid carcinoma	RET	1	Link
n/a	Rheumatoid arthritis	TEK	1	Link
	Loeys-Dietz syndrome	TGFBR1	1	Link
n/a	Familial thoracic aortic aneurysm and dissection	TGFBR1	1	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	1	Link
	Multiple self-healing squamous epithelioma	TGFBR1	1	Link
	Venous malformations	TEK	1	Link
n/a	Transient erythroblastopenia of childhood	TEC	1	Link
	Multiple endocrine neoplasia	RET	1	Link
	Pheochromocytoma	RET	1	Link
	Renal agenesis	RET	1	Link
n/a	Basal cell carcinoma	STK36	1	Link
	Colon cancer	SRC	59	Link
n/a	Pertussis	MAPK14	16	Link
n/a	Salmonella infection	MAPK14	16	Link
n/a	Achondroplasia	FGFR3	5	Link
n/a	Hypochondroplasia	FGFR3	5	Link
n/a	Muenke syndrome	FGFR3	5	Link
n/a	Nevus	FGFR3	5	Link
n/a	CATSHL syndrome	FGFR3	5	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	5	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	1	Link
	Craniosynostosis	FGFR2	1	Link
n/a	Saethre-Chotzen syndrome	FGFR2	1	Link
n/a	Multiple myeloma	FGFR3	5	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	1	Link
n/a	Spermatocytic seminoma	FGFR3	5	Link
n/a	Thanatophoric dysplasia	FGFR3	5	Link
	Piebaldism	KIT	9	Link
n/a	Germ cell tumors	KIT	9	Link
	Mast cell leukemia	KIT	9	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	16	Link
	Mastocytosis with associated hematologic disorder	KIT	9	Link
	Thrombocythemia	JAK2	1	Link
	Myelofibrosis	JAK2	1	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link
n/a	Lymphedemas	FLT4	1	Link
n/a	Lymphedema	FLT4	1	Link
n/a	Budd-Chiari syndrome	JAK2	1	Link
	Polycythemia vera	JAK2	1	Link

BioXGEM.

KIDFamMap

Allelic Variants