Allelic Variants

There are no related allelic variants
Related diseases of KIF 1PKDA_UCN (PDB code: 1PKD, chain A)
Number of involved diseases in the family 118
Number of AKT3 related diseases 11
All kinase in this family  AKT3
Allelic
Variants		 Disease Description Involved kinases
(This family)		 Inhibitor of
Involved Kinases		 Search
Disease
n/aEpstein-Barr virus infectionAKT1, AKT2, AKT3, CDC2,
CDK2, CHUK, CSNK2A1,
CSNK2A2, EIF2AK2, FGR,
GSK3B, JAK1, JAK3, LYN,
MAP2K3, MAP2K6, MAP3K7,
MAPK10, MAPK12, MAPK13,
MAPK14, MAPK8, MAPK9		19Link
n/aInfluenza AAKT1, AKT2, AKT3, EIF2AK2,
GSK3B, IRAK4, JAK1, JAK2,
MAP2K1, MAP2K3, MAP2K6,
MAPK1, MAPK10, MAPK12,
MAPK13, MAPK14, MAPK8,
MAPK9, PRKCA, PRKCB		57Link
n/aMeaslesAKT1, AKT2, AKT3, CDK2,
CDK4, CDK6, CHUK, CSNK2A1,
CSNK2A2, EIF2AK2, FYN,
GSK3B, IRAK4, JAK1, JAK2,
JAK3, MAP3K7, PRKCQ		17Link
n/aTuberculosisAKT1, AKT2, AKT3, CAMK2A,
CAMK2B, CAMK2D, IRAK4, JAK1,
JAK2, MAPK1, MAPK10, MAPK12,
MAPK13, MAPK14, MAPK8,
MAPK9, PLK3, SRC		21Link
n/aToxoplasmosisAKT1, AKT2, AKT3, CHUK,
IRAK4, JAK1, JAK2, MAP2K3,
MAP2K6, MAP3K7, MAPK1,
MAPK10, MAPK12, MAPK13,
MAPK14, MAPK8, MAPK9		13Link
LeukemiaABL1, ABL2, AKT1, AKT2,
AKT3, CDK4, CDK6, CHUK,
JAK2, MAP2K1, MAPK1, PIM1,
PIM2, RPS6KB1, RPS6KB2		14Link
n/aHepatitis CAKT1, AKT2, AKT3, CHUK,
EIF2AK2, GSK3B, JAK1, MAPK1,
MAPK10, MAPK12, MAPK13,
MAPK14, MAPK8, MAPK9		13Link
n/aHerpes simplex infectionCDC2, CDK2, CHUK, CSNK2A1,
CSNK2A2, EIF2AK2, JAK1,
JAK2, MAP3K7, MAPK10, MAPK8,
MAPK9		15Link
Prostate cancerAKT1, AKT2, AKT3, CDK2,
CHEK2, CHUK, FGFR1, FGFR2,
GSK3B, MAP2K1, MAPK1, PDPK1		16Link
n/aShigellosisABL1, CHUK, MAPK1, MAPK10,
MAPK12, MAPK13, MAPK14,
MAPK8, MAPK9, ROCK1, ROCK2,
SRC		21Link
n/aChagas diseaseAKT1, AKT2, AKT3, CHUK,
IRAK4, MAPK1, MAPK10,
MAPK12, MAPK13, MAPK14,
MAPK8, MAPK9		10Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCHUK, LYN, MAPK10, MAPK12,
MAPK13, MAPK14, MAPK8,
MAPK9, MET, PAK1, SRC		22Link
n/aSalmonella infectionMAPK1, MAPK10, MAPK12,
MAPK13, MAPK14, MAPK8,
MAPK9, PKN1, PKN2, ROCK1,
ROCK2		13Link
n/aLeishmaniasisIRAK4, JAK1, JAK2, MAP3K7,
MAPK1, MAPK12, MAPK13,
MAPK14, PRKCB		13Link
MelanomaAKT1, AKT2, AKT3, CDK4,
CDK6, FGFR1, MAP2K1, MAPK1,
MET		12Link
n/aPertussisIRAK4, MAPK1, MAPK10,
MAPK12, MAPK13, MAPK14,
MAPK8, MAPK9		10Link
Diabetes mellitusAKT2, MAPK1, MAPK10, MAPK8,
MAPK9, PRKCD, PRKCE		13Link
Lung cancerAKT1, AKT2, AKT3, CDK2,
CDK4, CDK6, CHUK		11Link
n/aAmyotrophic lateral sclerosisMAP2K3, MAP2K6, MAPK12,
MAPK13, MAPK14		10Link
n/aAlcoholismCAMKK1, CAMKK2, MAP2K1,
MAPK1, NTRK2		11Link
n/aPathogenic Escherichia coli infectionABL1, FYN, PRKCA, ROCK1,
ROCK2		56Link
Mental retardationCASK, DYRK1A, PAK3, RPS6KA310Link
n/aPrion diseasesFYN, MAP2K1, MAPK111Link
n/aViral myocarditisABL1, ABL2, FYN12Link
n/aImmunodeficienciesJAK3, LCK, ZAP7014Link
Colon cancerAURKA, SRC19Link
Crouzon syndromeFGFR2, FGFR38Link
Breast cancerAKT1, CHEK28Link
n/aEpileptic encephalopathyCDKL5, MAPK106Link
n/aEarly infantile epileptic encephalopathyCDKL5, MAPK106Link
n/aBasal cell carcinomaGSK3B, STK369Link
Gastric cancerFGFR2, MET9Link
n/aCervical cancerCDK4, FGFR38Link
Ovarian cancerAKT1, AKT27Link
Colorectal cancerAKT1, FGFR37Link
n/aBladder cancerDAPK1, FGFR39Link
Pfeiffer syndromeFGFR1, FGFR29Link
Jackson-Weiss syndromeFGFR1, FGFR29Link
LADD syndromeFGFR2, FGFR38Link
NeuroblastomaNTRK2, NTRK38Link
SCIDJAK3, LCK14Link
n/aAfrican trypanosomiasisPRKCA, PRKCB50Link
n/aVibrio cholerae infectionPRKCA, PRKCB50Link
n/aNon-syndromic X-linked mental retardationPAK3, RPS6KA39Link
n/aAmoebiasisPRKCA, PRKCB50Link
n/aAutism suseptibilityMET8Link
n/aMaturity onset diabetes of the youngBLK8Link
n/aMalariaMET8Link
n/aCongenital myasthenic syndromeMUSK4Link
Hepatocellular carcinomaMET8Link
n/aFG syndromeCASK1Link
n/aMalignant melanomaCDK45Link
n/aMyasthenic syndromeMUSK4Link
Renal cell carcinomaMET8Link
Li-Fraumeni syndromeCHEK25Link
n/aAngelman syndrome-likeCDKL51Link
n/aCholangiocarcinomaMET8Link
n/aGliomaCDK45Link
n/aCocaine addictionCDK54Link
n/aPrader-Willi and Angelman syndromesCDKL51Link
n/aFamilial partial lipodystrophyAKT27Link
Hypoinsulinemic hypoglycemiaAKT27Link
n/aPituitary tumorPRKCA50Link
Glycogen storage diseasePHKG28Link
n/aCerebral infarctionPRKCH10Link
n/aPTEN hamartoma tumor syndromeAKT17Link
Selective T-cell defectZAP7010Link
n/aCoffin-Lowry syndromeRPS6KA37Link
n/aType I diabetes mellitusPRKCQ8Link
n/aCirrhosis due to liver phosphorylase kinase deficiencyPHKG28Link
n/aGlycogen storage diseasesPHKG28Link
OsteosarcomaCHEK25Link
n/aShort rib-polydactyly syndormeNEK13Link
n/aSchizophreniaAKT17Link
n/aProteus syndromeAKT17Link
n/aObesityNTRK28Link
n/aNephronophthisisNEK81Link
n/aNephronophthisis-medullary cystic kidney diseaseNEK81Link
Cardiofaciocutaneous syndromeMAP2K14Link
n/aInvasive pneumococcal diseaseIRAK44Link
n/aHypochondroplasiaFGFR37Link
n/aMuenke syndromeFGFR37Link
n/aNevusFGFR37Link
n/aAchondroplasiaFGFR37Link
n/aCATSHL syndromeFGFR37Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR28Link
n/aMultiple myelomaFGFR37Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR37Link
n/aSpermatocytic seminomaFGFR37Link
n/aThanatophoric dysplasiaFGFR37Link
n/aEndocrine-cerebroosteodysplasiaICK2Link
Lymphoproliferative syndromeITK5Link
IRAK4 deficiencyIRAK44Link
Polycythemia veraJAK29Link
n/aOguchi diseaseGRK14Link
n/aCancer progression/metastasisFGFR43Link
n/aBudd-Chiari syndromeJAK29Link
n/aCongenital stationary night blindnessGRK14Link
ScaphocephalyFGFR28Link
n/aSaethre-Chotzen syndromeFGFR28Link
Osteoglophonic dysplasiaFGFR19Link
TrigonocephalyFGFR19Link
REtinitis pigmentosaMAK1Link
Hypogonadotropic hypogonadismFGFR19Link
n/aSpondylometaepiphyseal dysplasiaDDR23Link
n/aCocoon syndromeCHUK6Link
n/aLegionellosisCLK18Link
n/aNoonan syndrome and related disordersMAP2K14Link
Kallmann syndromeFGFR19Link
ThrombocythemiaJAK29Link
CraniosynostosisFGFR28Link
n/aMyeloproliferative disorderJAK29Link
MyelofibrosisJAK29Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR28Link
Bent bone dysplasia syndromeFGFR28Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR28Link
Apert syndromeFGFR28Link
Beare-Stevenson cutis gyrata syndromeFGFR28Link