KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3PJ1A_LHL (PDB code: 3PJ1, chain A)
Number of involved diseases in the family	96
Number of BTK related diseases	4

All kinase in this family BTK

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	EGFR, FGFR2, IGF1R, PDGFRA, PDGFRB	44	Link
	Melanoma	EGFR, IGF1R, MET, PDGFRA, PDGFRB	50	Link
	Leukemia	ABL1, JAK2, KIT, PDGFRB	40	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, LYN, MET, SRC	51	Link
	Gastric cancer	EGFR, FGFR2, MET	13	Link
n/a	Epstein-Barr virus infection	LYN, SYK, TYK2	2	Link
n/a	Measles	FYN, JAK2, TYK2	1	Link
n/a	Glioma	EGFR, PDGFRA, PDGFRB	32	Link
n/a	Tuberculosis	JAK2, SRC, SYK	45	Link
	Lung cancer	ALK, EGFR, ROS1	6	Link
	Crouzon syndrome	FGFR2, FGFR3	6	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	7	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	32	Link
n/a	Toxoplasmosis	JAK2, TYK2	1	Link
n/a	Influenza A	JAK2, TYK2	1	Link
n/a	Herpes simplex infection	JAK2, TYK2	1	Link
	LADD syndrome	FGFR2, FGFR3	6	Link
n/a	Hepatitis C	EGFR, TYK2	6	Link
n/a	Shigellosis	ABL1, SRC	46	Link
n/a	Viral myocarditis	ABL1, FYN	6	Link
	Hemangioma	FLT4, KDR	9	Link
	Neuroblastoma	ALK, NTRK2	1	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN	6	Link
n/a	Cervical cancer	EGFR, FGFR3	9	Link
n/a	Bladder cancer	EGFR, FGFR3	9	Link
	Colorectal cancer	FGFR3	5	Link
n/a	Hypochondroplasia	FGFR3	5	Link
	Jackson-Weiss syndrome	FGFR2	2	Link
	Pfeiffer syndrome	FGFR2	2	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	5	Link
n/a	Achondroplasia	FGFR3	5	Link
n/a	CATSHL syndrome	FGFR3	5	Link
n/a	Multiple myeloma	FGFR3	5	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	2	Link
n/a	Saethre-Chotzen syndrome	FGFR2	2	Link
	Scaphocephaly	FGFR2	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	2	Link
	Craniosynostosis	FGFR2	2	Link
n/a	Oral cancer	EGFR	5	Link
n/a	Esophageal cancer	EGFR	5	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	2	Link
	Agammaglobulinemia	BTK	2	Link
n/a	Agammaglobulinemias	BTK	2	Link
n/a	Pituitary Dwarfism	BTK	2	Link
n/a	Choriocarcinoma	EGFR	5	Link
n/a	Laryngeal cancer	EGFR	5	Link
	Bent bone dysplasia syndrome	FGFR2	2	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	2	Link
n/a	Muenke syndrome	FGFR3	5	Link
	Apert syndrome	FGFR2	2	Link
	Adenocarcinoma of lung	EGFR	5	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	2	Link
n/a	Lymphedemas	FLT4	1	Link
n/a	Nevus	FGFR3	5	Link
n/a	Alcoholism	NTRK2	1	Link
n/a	Obesity	NTRK2	1	Link
n/a	Hypereosinophilic syndrome	PDGFRA	1	Link
	Hepatocellular carcinoma	MET	7	Link
n/a	Autism suseptibility	MET	7	Link
	SCID	LCK	36	Link
	Renal cell carcinoma	MET	7	Link
n/a	Cholangiocarcinoma	MET	7	Link
n/a	Malaria	MET	7	Link
n/a	Thyroid cancer	RET	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
	Renal agenesis	RET	2	Link
	Colon cancer	SRC	45	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	1	Link
	Pheochromocytoma	RET	2	Link
	Multiple endocrine neoplasia	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
n/a	Medullary thyroid carcinoma	RET	2	Link
n/a	Immunodeficiencies	LCK	36	Link
	Mastocytosis with associated hematologic disorder	KIT	7	Link
n/a	Synovial sarcoma	IGF1R	12	Link
	Insulin-like growth factor I	IGF1R	12	Link
n/a	Leprechaunism	INSR	5	Link
n/a	Malignant pleural mesothelioma	IGF1R	12	Link
n/a	Prion diseases	FYN	1	Link
n/a	Spermatocytic seminoma	FGFR3	5	Link
n/a	Thanatophoric dysplasia	FGFR3	5	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link
n/a	Lymphedema	FLT4	1	Link
	Rabson-Mendenhall syndrome	INSR	5	Link
	Diabetes mellitus	INSR	5	Link
	Piebaldism	KIT	7	Link
n/a	Germ cell tumors	KIT	7	Link
	Mast cell leukemia	KIT	7	Link
	Thrombocythemia	JAK2	1	Link
	Myelofibrosis	JAK2	1	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link
	Polycythemia vera	JAK2	1	Link
n/a	Leishmaniasis	JAK2	1	Link
n/a	Budd-Chiari syndrome	JAK2	1	Link

BioXGEM.

KIDFamMap

Allelic Variants