Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
53 |
| Number of CHEK1 related diseases |
0 |
All kinase in this family
CHEK1
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| n/a | Measles | AKT2, AKT3, CDK2, CDK4,
CDK6, CSNK2A1, CSNK2A2,
GSK3B, IKBKE, IRAK4, JAK1,
PRKCQ, TBK1 | 3 | Link | | n/a | Epstein-Barr virus infection | AKT2, AKT3, CDC2, CDK2,
CSNK2A1, CSNK2A2, GSK3B,
JAK1, LYN, PRKACA, PRKACG,
PRKX, TBK1 | 2 | Link | | n/a | Influenza A | AKT2, AKT3, GSK3B, IKBKE,
IRAK4, JAK1, PRKCA, PRKCB,
TBK1 | 2 | Link | | Leukemia | AKT2, AKT3, CDK4, CDK6,
PIM1, PIM2, RPS6KB1, RPS6KB2 | 3 | Link | | n/a | Tuberculosis | AKT2, AKT3, CAMK2A, CAMK2B,
CAMK2D, CAMK2G, IRAK4, JAK1 | 1 | Link | | n/a | Herpes simplex infection | CDC2, CDK2, CSNK2A1,
CSNK2A2, IKBKE, JAK1, TBK1 | 2 | Link | | n/a | Hepatitis C | AKT2, AKT3, GSK3B, IKBKE,
JAK1, TBK1 | 1 | Link | | Prostate cancer | AKT2, AKT3, CDK2, CHEK2,
GSK3B, PDPK1 | 2 | Link | | Lung cancer | AKT2, AKT3, CDK2, CDK4, CDK6 | 3 | Link | | n/a | Vibrio cholerae infection | PRKACA, PRKACG, PRKCA,
PRKCB, PRKX | 2 | Link | | n/a | Amoebiasis | PRKACA, PRKACG, PRKCA,
PRKCB, PRKX | 2 | Link | | n/a | Cocaine addiction | CDK5, PRKACA, PRKACG, PRKX | 1 | Link | | n/a | Toxoplasmosis | AKT2, AKT3, IRAK4, JAK1 | 1 | Link | | n/a | Alcoholism | CAMKK1, CAMKK2, NTRK2,
PRKACA | 1 | Link | | Melanoma | AKT2, AKT3, CDK4, CDK6 | 3 | Link | | n/a | Leishmaniasis | IRAK4, JAK1, PRKCB | 1 | Link | | Diabetes mellitus | AKT2, PRKCD, PRKCE | 1 | Link | | Neuroblastoma | NTRK1, NTRK2, NTRK3 | 1 | Link | | n/a | Prion diseases | PRKACA, PRKACG, PRKX | 1 | Link | | n/a | Chagas disease | AKT2, AKT3, IRAK4 | 1 | Link | | n/a | Cardiomyopathy | PRKACA, PRKACG, PRKX | 1 | Link | | n/a | Non-syndromic X-linked mental retardation | PAK3, RPS6KA3 | 1 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | LYN, PAK1 | 1 | Link | | n/a | African trypanosomiasis | PRKCA, PRKCB | 2 | Link | | Mental retardation | PAK3, RPS6KA3 | 1 | Link | | n/a | Salmonella infection | PKN1, PKN2 | 1 | Link | | n/a | Familial partial lipodystrophy | AKT2 | 1 | Link | | n/a | Cervical cancer | CDK4 | 3 | Link | | Colon cancer | AURKA | 1 | Link | | n/a | Maturity onset diabetes of the young | BLK | 1 | Link | | Hypoinsulinemic hypoglycemia | AKT2 | 1 | Link | | n/a | Malignant melanoma | CDK4 | 3 | Link | | n/a | Bladder cancer | DAPK1 | 1 | Link | | n/a | Glioma | CDK4 | 3 | Link | | n/a | Obesity | NTRK2 | 1 | Link | | n/a | Medullary thyroid carcinoma | NTRK1 | 1 | Link | | n/a | Insensitivity to pain | NTRK1 | 1 | Link | | n/a | Pathogenic Escherichia coli infection | PRKCA | 2 | Link | | n/a | Pituitary tumor | PRKCA | 2 | Link | | n/a | Coffin-Lowry syndrome | RPS6KA3 | 1 | Link | | n/a | Type I diabetes mellitus | PRKCQ | 1 | Link | | n/a | Cerebral infarction | PRKCH | 1 | Link | | n/a | Thyroid cancer | NTRK1 | 1 | Link | | n/a | Nephronophthisis | NEK8 | 1 | Link | | Osteosarcoma | CHEK2 | 1 | Link | | Breast cancer | CHEK2 | 1 | Link | | Li-Fraumeni syndrome | CHEK2 | 1 | Link | | Ovarian cancer | AKT2 | 1 | Link | | n/a | Basal cell carcinoma | GSK3B | 1 | Link | | n/a | Nephronophthisis-medullary cystic kidney disease | NEK8 | 1 | Link | | IRAK4 deficiency | IRAK4 | 1 | Link | | n/a | Invasive pneumococcal disease | IRAK4 | 1 | Link | | n/a | Pertussis | IRAK4 | 1 | Link |
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