Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
52 |
| Number of CHEK1 related diseases |
0 |
All kinase in this family
CHEK1
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| n/a | Epstein-Barr virus infection | AKT1, AKT2, CDC2, CDK2,
CSNK2A1, GSK3B, LYN, MAPK14 | 41 | Link | | n/a | Measles | AKT1, AKT2, CDK2, CDK4,
CSNK2A1, GSK3B, PRKCQ | 34 | Link | | n/a | Influenza A | AKT1, AKT2, GSK3B, MAPK14,
PRKCA, PRKCB | 18 | Link | | Prostate cancer | AKT1, AKT2, BRAF, CDK2,
GSK3B, PDPK1 | 22 | Link | | Melanoma | AKT1, AKT2, BRAF, CDK4,
STK11 | 20 | Link | | Leukemia | AKT1, AKT2, BRAF, CDK4, PIM1 | 20 | Link | | Lung cancer | AKT1, AKT2, BRAF, CDK2, CDK4 | 32 | Link | | n/a | Hepatitis C | AKT1, AKT2, BRAF, GSK3B,
MAPK14 | 15 | Link | | n/a | Tuberculosis | AKT1, AKT2, MAPK14, SRC | 22 | Link | | n/a | Chagas disease | AKT1, AKT2, MAPK14 | 13 | Link | | n/a | Herpes simplex infection | CDC2, CDK2, CSNK2A1 | 22 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | LYN, MAPK14, SRC | 20 | Link | | Diabetes mellitus | AKT2, PRKCD, PRKCZ | 8 | Link | | n/a | Toxoplasmosis | AKT1, AKT2, MAPK14 | 13 | Link | | n/a | African trypanosomiasis | PRKCA, PRKCB | 5 | Link | | Ovarian cancer | AKT1, AKT2 | 2 | Link | | n/a | Thyroid cancer | BRAF, NTRK1 | 3 | Link | | Colon cancer | AURKA, SRC | 28 | Link | | Colorectal cancer | AKT1, BRAF | 3 | Link | | n/a | Malignant melanoma | BRAF, CDK4 | 17 | Link | | n/a | Vibrio cholerae infection | PRKCA, PRKCB | 5 | Link | | n/a | Amoebiasis | PRKCA, PRKCB | 5 | Link | | n/a | Leishmaniasis | MAPK14, PRKCB | 12 | Link | | n/a | Shigellosis | MAPK14, SRC | 20 | Link | | n/a | Schizophrenia | AKT1 | 2 | Link | | n/a | Proteus syndrome | AKT1 | 2 | Link | | Hypoinsulinemic hypoglycemia | AKT2 | 2 | Link | | n/a | Familial partial lipodystrophy | AKT2 | 2 | Link | | Breast cancer | AKT1 | 2 | Link | | Adenocarcinoma of lung | BRAF | 1 | Link | | n/a | Noonan syndrome and related disorders | BRAF | 1 | Link | | n/a | Medullary thyroid carcinoma | NTRK1 | 2 | Link | | n/a | Insensitivity to pain | NTRK1 | 2 | Link | | Neuroblastoma | NTRK1 | 2 | Link | | n/a | Pathogenic Escherichia coli infection | PRKCA | 5 | Link | | n/a | Pituitary tumor | PRKCA | 5 | Link | | n/a | Testicular tumor | STK11 | 1 | Link | | n/a | Peutz-Jeghers syndrome | STK11 | 1 | Link | | n/a | Pancreatic cancer | STK11 | 1 | Link | | n/a | Type I diabetes mellitus | PRKCQ | 1 | Link | | n/a | Pertussis | MAPK14 | 11 | Link | | n/a | Salmonella infection | MAPK14 | 11 | Link | | LEOPARD syndrome | BRAF | 1 | Link | | Cardiofaciocutaneous syndrome | BRAF | 1 | Link | | n/a | PTEN hamartoma tumor syndrome | AKT1 | 2 | Link | | n/a | Alcoholism | BRAF | 1 | Link | | Noonan syndrome | BRAF | 1 | Link | | n/a | Cervical cancer | CDK4 | 16 | Link | | n/a | Amyotrophic lateral sclerosis | MAPK14 | 11 | Link | | n/a | Basal cell carcinoma | GSK3B | 1 | Link | | n/a | Cocaine addiction | CDK5 | 1 | Link | | n/a | Glioma | CDK4 | 16 | Link |
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