KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2HXLA_422 (PDB code: 2HXL, chain A)
Number of involved diseases in the family	36
Number of CHEK1 related diseases	0

All kinase in this family CHEK1

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Measles	AKT1, AKT2, CDK2, CDK4, GSK3B, PRKCQ	57	Link
n/a	Epstein-Barr virus infection	AKT1, AKT2, CDC2, CDK2, GSK3B	35	Link
	Prostate cancer	AKT1, AKT2, BRAF, CDK2, GSK3B	40	Link
	Lung cancer	AKT1, AKT2, BRAF, CDK2, CDK4	40	Link
	Leukemia	AKT1, AKT2, BRAF, CDK4	36	Link
	Melanoma	AKT1, AKT2, BRAF, CDK4	36	Link
n/a	Hepatitis C	AKT1, AKT2, BRAF, GSK3B	36	Link
n/a	Influenza A	AKT1, AKT2, GSK3B	27	Link
	Diabetes mellitus	AKT2, PRKCD, PRKCZ	52	Link
n/a	Tuberculosis	AKT1, AKT2, SRC	30	Link
n/a	Malignant melanoma	BRAF, CDK4	10	Link
	Colorectal cancer	AKT1, BRAF	35	Link
	Colon cancer	AURKA, SRC	6	Link
n/a	Chagas disease	AKT1, AKT2	26	Link
	Ovarian cancer	AKT1, AKT2	26	Link
n/a	Herpes simplex infection	CDC2, CDK2	9	Link
n/a	Toxoplasmosis	AKT1, AKT2	26	Link
	Breast cancer	AKT1	26	Link
n/a	Proteus syndrome	AKT1	26	Link
n/a	Familial partial lipodystrophy	AKT2	26	Link
n/a	Schizophrenia	AKT1	26	Link
n/a	Glioma	CDK4	1	Link
n/a	Cervical cancer	CDK4	1	Link
n/a	Basal cell carcinoma	GSK3B	1	Link
n/a	Type I diabetes mellitus	PRKCQ	26	Link
n/a	Shigellosis	SRC	4	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	SRC	4	Link
	Noonan syndrome	BRAF	9	Link
	LEOPARD syndrome	BRAF	9	Link
	Hypoinsulinemic hypoglycemia	AKT2	26	Link
n/a	PTEN hamartoma tumor syndrome	AKT1	26	Link
n/a	Thyroid cancer	BRAF	9	Link
n/a	Noonan syndrome and related disorders	BRAF	9	Link
	Cardiofaciocutaneous syndrome	BRAF	9	Link
	Adenocarcinoma of lung	BRAF	9	Link
n/a	Alcoholism	BRAF	9	Link

BioXGEM.