Allelic Variants

There are no related allelic variants
Related diseases of KIF 2H8HA_H8H (PDB code: 2H8H, chain A)
Number of involved diseases in the family 126
Number of DDR1 related diseases 0
All kinase in this family  DDR1
Allelic
Variants		 Disease Description Involved kinases
(This family)		 Inhibitor of
Involved Kinases		 Search
Disease
Prostate cancerEGFR, EPHB2, ERBB2, FGFR1,
FGFR2, IGF1R, INSRR, PDGFRA,
PDGFRB		73Link
n/aMeaslesFYN, IRAK1, IRAK4, JAK2,
JAK3, PRKCQ, TYK2		8Link
n/aEpstein-Barr virus infectionFGR, IRAK1, JAK3, LYN,
MAPK14, SYK, TYK2		11Link
n/aTuberculosisIRAK1, IRAK4, JAK2, MAPK14,
SRC, SYK		173Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCSK, EGFR, LYN, MAPK14, SRC227Link
n/aInfluenza AIRAK4, JAK2, MAPK14, PRKCA,
TYK2		8Link
n/aToxoplasmosisIRAK1, IRAK4, JAK2, MAPK14,
TYK2		7Link
LeukemiaABL1, ABL2, JAK2, KIT,
PDGFRB		28Link
MelanomaEGFR, FGFR1, IGF1R, PDGFRA,
PDGFRB		73Link
NeuroblastomaALK, NTRK1, NTRK2, NTRK316Link
n/aLeishmaniasisIRAK1, IRAK4, JAK2, MAPK147Link
n/aHepatitis CEGFR, MAPK14, TYK270Link
n/aGliomaEGFR, PDGFRA, PDGFRB68Link
n/aCervical cancerEGFR, ERBB2, FGFR368Link
n/aBladder cancerEGFR, ERBB2, FGFR368Link
n/aImmunodeficienciesJAK3, LCK, ZAP7018Link
Gastric cancerEGFR, ERBB2, FGFR268Link
n/aChagas diseaseIRAK1, IRAK4, MAPK147Link
n/aChoriocarcinomaCSF1R, EGFR, ERBB268Link
n/aViral myocarditisABL1, ABL2, FYN25Link
n/aShigellosisABL1, MAPK14, SRC174Link
n/aPertussisIRAK1, IRAK4, MAPK147Link
n/aPathogenic Escherichia coli infectionABL1, FYN, PRKCA25Link
LADD syndromeFGFR2, FGFR34Link
SCIDJAK3, LCK18Link
Crouzon syndromeFGFR2, FGFR34Link
Adenocarcinoma of lungEGFR, ERBB268Link
Diabetes mellitusINSR, PRKCD10Link
n/aType I diabetes mellitusERBB3, PRKCQ3Link
Jackson-Weiss syndromeFGFR1, FGFR228Link
Pfeiffer syndromeFGFR1, FGFR228Link
n/aHerpes simplex infectionJAK2, TYK21Link
n/aMyeloproliferative disorderJAK2, PDGFRB6Link
n/aThyroid cancerNTRK1, RET8Link
Gastrointestinal stromal tumorKIT, PDGFRA11Link
Lung cancerALK, EGFR78Link
n/aMedullary thyroid carcinomaNTRK1, RET8Link
n/aSalmonella infectionMAPK14, PKN23Link
Osteoglophonic dysplasiaFGFR128Link
Kallmann syndromeFGFR128Link
n/aMaturity onset diabetes of the youngBLK8Link
TrigonocephalyFGFR128Link
n/aChrondrodysplasiaBMPR1B1Link
BrachydactylyBMPR1B1Link
Apert syndromeFGFR24Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR24Link
Hereditary hemorrhagic telangiectasiaACVRL13Link
Fibrodysplasia ossificans progressivaACVR13Link
CraniosynostosisFGFR24Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR24Link
n/aTelangiectasia, hereditary hemorrhagicACVRL13Link
Beare-Stevenson cutis gyrata syndromeFGFR24Link
Bent bone dysplasia syndromeFGFR24Link
n/aLethal congenital contractural syndromeERBB33Link
Hypogonadotropic hypogonadismFGFR128Link
Breast cancerERBB29Link
n/aCholangiocarcinomaERBB29Link
Ovarian cancerERBB29Link
Endometrial CancerERBB29Link
n/aLaryngeal cancerEGFR68Link
n/aSaethre-Chotzen syndromeFGFR24Link
n/aPancreatic cancerERBB29Link
n/aEsophageal cancerEGFR68Link
n/aOral cancerEGFR68Link
n/aPituitary DwarfismBTK5Link
n/aAgammaglobulinemiasBTK5Link
GlioblastomaERBB29Link
AgammaglobulinemiaBTK5Link
n/aSpondylometaepiphyseal dysplasiaDDR24Link
n/aLeukoencephalopathy, diffuse hereditary, with spheroidsCSF1R6Link
n/aAgammaglobulinemia and isolated hormone deficiencyBTK5Link
n/aMuenke syndromeFGFR33Link
ScaphocephalyFGFR24Link
n/aAfrican trypanosomiasisPRKCA1Link
n/aAmoebiasisPRKCA1Link
n/aPituitary tumorPRKCA1Link
n/aRenal agenesis and Renal adysplasiaRET7Link
n/aVibrio cholerae infectionPRKCA1Link
n/aHypereosinophilic syndromePDGFRA5Link
Mastocytosis with associated hematologic disorderKIT10Link
n/aAmyotrophic lateral sclerosisMAPK142Link
n/aInsensitivity to painNTRK12Link
n/aObesityNTRK22Link
n/aAlcoholismNTRK22Link
Hirschsprung diseaseRET7Link
n/aCongenital central hypoventilation syndromeRET7Link
Colon cancerSRC173Link
n/aBasal cell carcinomaSTK362Link
n/aTransient erythroblastopenia of childhoodTEC2Link
Selective T-cell defectZAP701Link
n/aTyrosine kinase 2 deficiencyTYK21Link
Mental retardationRPS6KA31Link
n/aCoffin-Lowry syndromeRPS6KA31Link
Central hypoventilation syndromeRET7Link
Multiple endocrine neoplasiaRET7Link
PheochromocytomaRET7Link
n/aNon-syndromic X-linked mental retardationRPS6KA31Link
Renal agenesisRET7Link
Mast cell leukemiaKIT10Link
n/aGerm cell tumorsKIT10Link
n/aNevusFGFR33Link
n/aSpermatocytic seminomaFGFR33Link
n/aThanatophoric dysplasiaFGFR33Link
n/aPrion diseasesFYN7Link
n/aCancer progression/metastasisFGFR41Link
n/aHypochondroplasiaFGFR33Link
Colorectal cancerFGFR33Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR24Link
n/aMultiple myelomaFGFR33Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR33Link
n/aAchondroplasiaFGFR33Link
n/aCATSHL syndromeFGFR33Link
n/aMalignant pleural mesotheliomaIGF1R3Link
n/aSynovial sarcomaIGF1R3Link
Polycythemia veraJAK21Link
n/aBudd-Chiari syndromeJAK21Link
MyelofibrosisJAK21Link
PiebaldismKIT10Link
ThrombocythemiaJAK21Link
Lymphoproliferative syndromeITK1Link
IRAK4 deficiencyIRAK45Link
Insulin-like growth factor IIGF1R3Link
n/aLeprechaunismINSR8Link
Rabson-Mendenhall syndromeINSR8Link
n/aInvasive pneumococcal diseaseIRAK45Link
Hyperinsulinemic hypoglycemiaINSR8Link