KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2VWUA_7X1 (PDB code: 2VWU, chain A)
Number of involved diseases in the family	111
Number of DDR1 related diseases	0

All kinase in this family DDR1

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	EGFR, EPHB2, FGFR1, FGFR2, IGF1R, INSRR	94	Link
n/a	Tuberculosis	IRAK1, IRAK4, JAK2, SRC, SYK	186	Link
n/a	Measles	FYN, IRAK1, IRAK4, JAK2, TYK2	9	Link
n/a	Epstein-Barr virus infection	FGR, IRAK1, LYN, SYK, TYK2	10	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	14	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, LYN, SRC	261	Link
	Leukemia	ABL1, ABL2, JAK2, TGFBR1	26	Link
n/a	Toxoplasmosis	IRAK1, IRAK4, JAK2, TYK2	5	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	26	Link
	Melanoma	EGFR, FGFR1, IGF1R	94	Link
n/a	Leishmaniasis	IRAK1, IRAK4, JAK2	5	Link
n/a	Influenza A	IRAK4, JAK2, TYK2	5	Link
n/a	Chagas disease	IRAK1, IRAK4, TGFBR1	6	Link
n/a	Cervical cancer	EGFR, FGFR3	91	Link
	Hemangioma	FLT4, KDR	86	Link
n/a	Hepatitis C	EGFR, TYK2	91	Link
n/a	Pertussis	IRAK1, IRAK4	5	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	29	Link
	Pfeiffer syndrome	FGFR1, FGFR2	29	Link
n/a	Immunodeficiencies	LCK, ZAP70	19	Link
n/a	Herpes simplex infection	JAK2, TYK2	1	Link
n/a	Bladder cancer	EGFR, FGFR3	91	Link
n/a	Choriocarcinoma	CSF1R, EGFR	91	Link
	LADD syndrome	FGFR2, FGFR3	5	Link
	Lung cancer	ALK, EGFR	98	Link
n/a	Shigellosis	ABL1, SRC	186	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN	26	Link
	Crouzon syndrome	FGFR2, FGFR3	5	Link
	Gastric cancer	EGFR, FGFR2	91	Link
n/a	Thyroid cancer	NTRK1, RET	9	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	9	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	5	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	5	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	5	Link
	Kallmann syndrome	FGFR1	29	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	5	Link
	Scaphocephaly	FGFR2	5	Link
	Bent bone dysplasia syndrome	FGFR2	5	Link
	Craniosynostosis	FGFR2	5	Link
	Trigonocephaly	FGFR1	29	Link
	Apert syndrome	FGFR2	5	Link
n/a	Saethre-Chotzen syndrome	FGFR2	5	Link
	Cataract	EPHA2	6	Link
	Osteoglophonic dysplasia	FGFR1	29	Link
	Agammaglobulinemia	BTK	6	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	6	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	7	Link
n/a	Pituitary Dwarfism	BTK	6	Link
n/a	Agammaglobulinemias	BTK	6	Link
	Fibrodysplasia ossificans progressiva	ACVR1	4	Link
n/a	Pancreatic cancer	ACVR1B	1	Link
n/a	Maturity onset diabetes of the young	BLK	9	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	5	Link
n/a	Oral cancer	EGFR	91	Link
n/a	Type I diabetes mellitus	ERBB3	4	Link
n/a	Lethal congenital contractural syndrome	ERBB3	4	Link
	Hypogonadotropic hypogonadism	FGFR1	29	Link
n/a	Multiple myeloma	FGFR3	4	Link
	Adenocarcinoma of lung	EGFR	91	Link
n/a	Esophageal cancer	EGFR	91	Link
n/a	Glioma	EGFR	91	Link
n/a	Laryngeal cancer	EGFR	91	Link
n/a	Nevus	FGFR3	4	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	4	Link
n/a	Renal agenesis and Renal adysplasia	RET	8	Link
	Hirschsprung disease	RET	8	Link
n/a	Congenital central hypoventilation syndrome	RET	8	Link
	Central hypoventilation syndrome	RET	8	Link
n/a	Obesity	NTRK2	2	Link
n/a	Alcoholism	NTRK2	2	Link
n/a	Myeloproliferative disorder	JAK2	1	Link
	Thrombocythemia	JAK2	1	Link
	SCID	LCK	19	Link
n/a	Insensitivity to pain	NTRK1	2	Link
	Multiple endocrine neoplasia	RET	8	Link
	Pheochromocytoma	RET	8	Link
n/a	Familial thoracic aortic aneurysm and dissection	TGFBR1	1	Link
	Multiple self-healing squamous epithelioma	TGFBR1	1	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	1	Link
	Selective T-cell defect	ZAP70	1	Link
	Loeys-Dietz syndrome	TGFBR1	1	Link
n/a	Rheumatoid arthritis	TEK	10	Link
	Renal agenesis	RET	8	Link
	Colon cancer	SRC	186	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
	Venous malformations	TEK	10	Link
	Myelofibrosis	JAK2	1	Link
n/a	Budd-Chiari syndrome	JAK2	1	Link
n/a	Thanatophoric dysplasia	FGFR3	4	Link
n/a	Cancer progression/metastasis	FGFR4	2	Link
n/a	Lymphedemas	FLT4	9	Link
n/a	Lymphedema	FLT4	9	Link
n/a	Spermatocytic seminoma	FGFR3	4	Link
n/a	Muenke syndrome	FGFR3	4	Link
n/a	CATSHL syndrome	FGFR3	4	Link
n/a	Achondroplasia	FGFR3	4	Link
	Colorectal cancer	FGFR3	4	Link
n/a	Hypochondroplasia	FGFR3	4	Link
n/a	Prion diseases	FYN	8	Link
n/a	Malignant pleural mesothelioma	IGF1R	1	Link
n/a	Invasive pneumococcal disease	IRAK4	5	Link
	IRAK4 deficiency	IRAK4	5	Link
	Lymphoproliferative syndrome	ITK	1	Link
	Polycythemia vera	JAK2	1	Link
n/a	Asthma susceptibility	IRAK3	2	Link
	Hyperinsulinemic hypoglycemia	INSR	6	Link
n/a	Synovial sarcoma	IGF1R	1	Link
	Insulin-like growth factor I	IGF1R	1	Link
n/a	Leprechaunism	INSR	6	Link
	Diabetes mellitus	INSR	6	Link
	Rabson-Mendenhall syndrome	INSR	6	Link

BioXGEM.

KIDFamMap

Allelic Variants