KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2OFUA_1N9 (PDB code: 2OFU, chain A)
Number of involved diseases in the family	101
Number of DDR2 related diseases	1

All kinase in this family DDR2

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	BRAF, EGFR, EPHB2, FGFR1, FGFR2, IGF1R, PDGFRA, PDGFRB, RAF1	70	Link
	Melanoma	BRAF, EGFR, FGFR1, IGF1R, PDGFRA, PDGFRB, RAF1	69	Link
	Leukemia	ABL1, ABL2, BRAF, JAK2, KIT, PDGFRB, RAF1	41	Link
n/a	Tuberculosis	JAK2, MAPK14, PLK3, RAF1, SRC, SYK	93	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, LYN, MAPK14, SRC	103	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	11	Link
n/a	Influenza A	JAK2, MAPK14, PRKCB, RAF1	54	Link
n/a	Hepatitis C	BRAF, EGFR, MAPK14, RAF1	69	Link
n/a	Alcoholism	BRAF, NTRK2, RAF1	6	Link
n/a	Glioma	EGFR, PDGFRA, PDGFRB	44	Link
n/a	Thyroid cancer	BRAF, NTRK1, RET	6	Link
n/a	Epstein-Barr virus infection	LYN, MAPK14, SYK	53	Link
n/a	Leishmaniasis	JAK2, MAPK14, PRKCB	52	Link
n/a	Shigellosis	ABL1, MAPK14, SRC	91	Link
	Lung cancer	ALK, BRAF, EGFR	23	Link
	Noonan syndrome	BRAF, RAF1	4	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	30	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	15	Link
n/a	Toxoplasmosis	JAK2, MAPK14	51	Link
	Gastric cancer	EGFR, FGFR2	19	Link
n/a	Choriocarcinoma	CSF1R, EGFR	29	Link
	LEOPARD syndrome	BRAF, RAF1	4	Link
	Colon cancer	AURKA, SRC	92	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	6	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	14	Link
	Adenocarcinoma of lung	BRAF, EGFR	18	Link
	Pfeiffer syndrome	FGFR1, FGFR2	14	Link
n/a	Viral myocarditis	ABL1, ABL2	9	Link
n/a	Esophageal cancer	EGFR	18	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	1	Link
	Kallmann syndrome	FGFR1	13	Link
n/a	Bladder cancer	EGFR	18	Link
	Osteoglophonic dysplasia	FGFR1	13	Link
	Hypogonadotropic hypogonadism	FGFR1	13	Link
	Cataract	EPHA2	2	Link
n/a	Laryngeal cancer	EGFR	18	Link
n/a	Cervical cancer	EGFR	18	Link
	Trigonocephaly	FGFR1	13	Link
n/a	Cocaine addiction	CDK5	2	Link
n/a	Oral cancer	EGFR	18	Link
n/a	Noonan syndrome and related disorders	BRAF	2	Link
	Cardiofaciocutaneous syndrome	BRAF	2	Link
n/a	Malignant melanoma	BRAF	2	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
n/a	Pathogenic Escherichia coli infection	ABL1	9	Link
	Fibrodysplasia ossificans progressiva	ACVR1	2	Link
	Colorectal cancer	BRAF	2	Link
n/a	Agammaglobulinemias	BTK	2	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	15	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	3	Link
	Apert syndrome	FGFR2	1	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	2	Link
n/a	Pituitary Dwarfism	BTK	2	Link
	Agammaglobulinemia	BTK	2	Link
	Crouzon syndrome	FGFR2	1	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	1	Link
n/a	Congenital myasthenic syndrome	MUSK	2	Link
n/a	Myasthenic syndrome	MUSK	2	Link
n/a	Insensitivity to pain	NTRK1	6	Link
n/a	Chagas disease	MAPK14	51	Link
n/a	Pertussis	MAPK14	51	Link
n/a	Immunodeficiencies	LCK	46	Link
	SCID	LCK	46	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	51	Link
n/a	Salmonella infection	MAPK14	51	Link
n/a	Obesity	NTRK2	4	Link
n/a	Hypereosinophilic syndrome	PDGFRA	7	Link
	Central hypoventilation syndrome	RET	2	Link
	Multiple endocrine neoplasia	RET	2	Link
	Pheochromocytoma	RET	2	Link
	Renal agenesis	RET	2	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Vibrio cholerae infection	PRKCB	1	Link
n/a	African trypanosomiasis	PRKCB	1	Link
n/a	Amoebiasis	PRKCB	1	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
	Mastocytosis with associated hematologic disorder	KIT	15	Link
	Mast cell leukemia	KIT	15	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	1	Link
n/a	Malignant pleural mesothelioma	IGF1R	14	Link
n/a	Synovial sarcoma	IGF1R	14	Link
	Insulin-like growth factor I	IGF1R	14	Link
	Scaphocephaly	FGFR2	1	Link
n/a	Saethre-Chotzen syndrome	FGFR2	1	Link
	Bent bone dysplasia syndrome	FGFR2	1	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	1	Link
	Craniosynostosis	FGFR2	1	Link
	LADD syndrome	FGFR2	1	Link
n/a	Leprechaunism	INSR	7	Link
	Rabson-Mendenhall syndrome	INSR	7	Link
	Myelofibrosis	JAK2	1	Link
	Thrombocythemia	JAK2	1	Link
	Piebaldism	KIT	15	Link
n/a	Germ cell tumors	KIT	15	Link
n/a	Budd-Chiari syndrome	JAK2	1	Link
n/a	Herpes simplex infection	JAK2	1	Link
	Diabetes mellitus	INSR	7	Link
	Hyperinsulinemic hypoglycemia	INSR	7	Link
	Polycythemia vera	JAK2	1	Link
n/a	Measles	JAK2	1	Link

BioXGEM.

KIDFamMap

Allelic Variants