KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3AOXA_EMH (PDB code: 3AOX, chain A)
Number of involved diseases in the family	85
Number of DDR2 related diseases	1

All kinase in this family DDR2

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	BRAF, EGFR, EPHB2, FGFR1, FGFR2, IGF1R	6	Link
	Melanoma	BRAF, EGFR, FGFR1, IGF1R, MET	6	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	17	Link
	Lung cancer	ALK, BRAF, EGFR, PTK2	19	Link
n/a	Thyroid cancer	BRAF, NTRK1, RET	4	Link
	Leukemia	ABL1, ABL2, BRAF	4	Link
	Gastric cancer	EGFR, FGFR2, MET	5	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, MET, SRC	5	Link
	Pfeiffer syndrome	FGFR1, FGFR2	3	Link
	Hemangioma	FLT4, KDR	6	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	3	Link
n/a	Choriocarcinoma	CSF1R, EGFR	6	Link
	Adenocarcinoma of lung	BRAF, EGFR	5	Link
n/a	Viral myocarditis	ABL1, ABL2	3	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	3	Link
n/a	Shigellosis	ABL1, SRC	3	Link
n/a	Alcoholism	BRAF, NTRK2	3	Link
n/a	Hepatitis C	BRAF, EGFR	5	Link
	Osteoglophonic dysplasia	FGFR1	2	Link
	Hypogonadotropic hypogonadism	FGFR1	2	Link
	Cataract	EPHA2	2	Link
	Bent bone dysplasia syndrome	FGFR2	1	Link
	Trigonocephaly	FGFR1	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	1	Link
n/a	Laryngeal cancer	EGFR	4	Link
	Kallmann syndrome	FGFR1	2	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	1	Link
	Apert syndrome	FGFR2	1	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	2	Link
n/a	Glioma	EGFR	4	Link
	Cardiofaciocutaneous syndrome	BRAF	3	Link
n/a	Noonan syndrome and related disorders	BRAF	3	Link
n/a	Malignant melanoma	BRAF	3	Link
n/a	Pathogenic Escherichia coli infection	ABL1	3	Link
n/a	Maturity onset diabetes of the young	BLK	2	Link
	Colorectal cancer	BRAF	3	Link
	LEOPARD syndrome	BRAF	3	Link
n/a	Bladder cancer	EGFR	4	Link
n/a	Cervical cancer	EGFR	4	Link
n/a	Esophageal cancer	EGFR	4	Link
n/a	Oral cancer	EGFR	4	Link
	Noonan syndrome	BRAF	3	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	4	Link
	Craniosynostosis	FGFR2	1	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	1	Link
n/a	Congenital myasthenic syndrome	MUSK	2	Link
n/a	Myasthenic syndrome	MUSK	2	Link
n/a	Insensitivity to pain	NTRK1	3	Link
	Hepatocellular carcinoma	MET	1	Link
n/a	Autism suseptibility	MET	1	Link
	Renal cell carcinoma	MET	1	Link
n/a	Cholangiocarcinoma	MET	1	Link
n/a	Malaria	MET	1	Link
n/a	Obesity	NTRK2	2	Link
n/a	Amoebiasis	PTK2	2	Link
	Renal agenesis	RET	2	Link
n/a	Tuberculosis	SRC	1	Link
	Colon cancer	SRC	1	Link
	Pheochromocytoma	RET	2	Link
	Multiple endocrine neoplasia	RET	2	Link
n/a	Renal agenesis and Renal adysplasia	RET	2	Link
	Hirschsprung disease	RET	2	Link
n/a	Congenital central hypoventilation syndrome	RET	2	Link
	Central hypoventilation syndrome	RET	2	Link
	Retinitis pigmentosa	MERTK	2	Link
n/a	Epstein-Barr virus infection	MAP3K7	1	Link
n/a	Lymphedemas	FLT4	2	Link
n/a	Lymphedema	FLT4	2	Link
n/a	Malignant pleural mesothelioma	IGF1R	1	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	1	Link
	Scaphocephaly	FGFR2	1	Link
	Crouzon syndrome	FGFR2	1	Link
	LADD syndrome	FGFR2	1	Link
n/a	Saethre-Chotzen syndrome	FGFR2	1	Link
n/a	Synovial sarcoma	IGF1R	1	Link
	Insulin-like growth factor I	IGF1R	1	Link
n/a	Toxoplasmosis	MAP3K7	1	Link
n/a	Measles	MAP3K7	1	Link
n/a	Herpes simplex infection	MAP3K7	1	Link
n/a	Leishmaniasis	MAP3K7	1	Link
	Lymphoproliferative syndrome	ITK	6	Link
n/a	Leprechaunism	INSR	2	Link
	Rabson-Mendenhall syndrome	INSR	2	Link
	Diabetes mellitus	INSR	2	Link
	Hyperinsulinemic hypoglycemia	INSR	2	Link

BioXGEM.

KIDFamMap

Allelic Variants