KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2ITTA_AEE (PDB code: 2ITT, chain A)
Number of involved diseases in the family	77
Number of EGFR related diseases	14

All kinase in this family EGFR

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	BRAF, EGFR, ERBB2, FGFR1, IGF1R, PDGFRA, PDGFRB, PDPK1	66	Link
	Melanoma	BRAF, EGFR, FGFR1, IGF1R, PDGFRA, PDGFRB	61	Link
	Leukemia	ABL1, BRAF, JAK2, KIT, PDGFRB	31	Link
n/a	Epstein-Barr virus infection	JAK3, LYN, SYK	22	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	EGFR, LYN, SRC	58	Link
	Adenocarcinoma of lung	BRAF, EGFR, ERBB2	33	Link
n/a	Glioma	EGFR, PDGFRA, PDGFRB	22	Link
n/a	Thyroid cancer	BRAF, NTRK1, RET	26	Link
	Lung cancer	ALK, BRAF, EGFR	32	Link
n/a	Tuberculosis	JAK2, SRC, SYK	55	Link
n/a	Immunodeficiencies	JAK3, LCK	28	Link
	Gastric cancer	EGFR, ERBB2	24	Link
n/a	Cervical cancer	EGFR, ERBB2	24	Link
n/a	Choriocarcinoma	EGFR, ERBB2	24	Link
n/a	Measles	JAK2, JAK3	6	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	6	Link
	SCID	JAK3, LCK	28	Link
n/a	Bladder cancer	EGFR, ERBB2	24	Link
	Colon cancer	AURKA, SRC	57	Link
	Neuroblastoma	ALK, NTRK1	4	Link
n/a	Shigellosis	ABL1, SRC	53	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	17	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	2	Link
n/a	Hepatitis C	BRAF, EGFR	29	Link
	Ovarian cancer	ERBB2	12	Link
n/a	Cholangiocarcinoma	ERBB2	12	Link
	Breast cancer	ERBB2	12	Link
	Endometrial Cancer	ERBB2	12	Link
n/a	Laryngeal cancer	EGFR	20	Link
n/a	Pancreatic cancer	ERBB2	12	Link
	Colorectal cancer	BRAF	9	Link
n/a	Esophageal cancer	EGFR	20	Link
n/a	Noonan syndrome and related disorders	BRAF	9	Link
n/a	Malignant melanoma	BRAF	9	Link
n/a	Viral myocarditis	ABL1	15	Link
n/a	Pathogenic Escherichia coli infection	ABL1	15	Link
n/a	Alcoholism	BRAF	9	Link
	Cardiofaciocutaneous syndrome	BRAF	9	Link
n/a	Oral cancer	EGFR	20	Link
	Noonan syndrome	BRAF	9	Link
	LEOPARD syndrome	BRAF	9	Link
	Glioblastoma	ERBB2	12	Link
	Kallmann syndrome	FGFR1	19	Link
	Hypogonadotropic hypogonadism	FGFR1	19	Link
	Mast cell leukemia	KIT	2	Link
	Mastocytosis with associated hematologic disorder	KIT	2	Link
n/a	Germ cell tumors	KIT	2	Link
	Piebaldism	KIT	2	Link
	Myelofibrosis	JAK2	5	Link
	Thrombocythemia	JAK2	5	Link
n/a	Insensitivity to pain	NTRK1	1	Link
n/a	Hypereosinophilic syndrome	PDGFRA	1	Link
	Pheochromocytoma	RET	16	Link
	Renal agenesis	RET	16	Link
	Multiple endocrine neoplasia	RET	16	Link
	Central hypoventilation syndrome	RET	16	Link
n/a	Renal agenesis and Renal adysplasia	RET	16	Link
	Hirschsprung disease	RET	16	Link
n/a	Congenital central hypoventilation syndrome	RET	16	Link
n/a	Budd-Chiari syndrome	JAK2	5	Link
n/a	Herpes simplex infection	JAK2	5	Link
n/a	Synovial sarcoma	IGF1R	14	Link
	Insulin-like growth factor I	IGF1R	14	Link
n/a	Malignant pleural mesothelioma	IGF1R	14	Link
	Pfeiffer syndrome	FGFR1	19	Link
	Osteoglophonic dysplasia	FGFR1	19	Link
	Trigonocephaly	FGFR1	19	Link
	Jackson-Weiss syndrome	FGFR1	19	Link
n/a	Leprechaunism	INSR	7	Link
	Rabson-Mendenhall syndrome	INSR	7	Link
n/a	Toxoplasmosis	JAK2	5	Link
n/a	Influenza A	JAK2	5	Link
n/a	Leishmaniasis	JAK2	5	Link
	Polycythemia vera	JAK2	5	Link
	Diabetes mellitus	INSR	7	Link
	Hyperinsulinemic hypoglycemia	INSR	7	Link
	Lymphoproliferative syndrome	ITK	3	Link

BioXGEM.

KIDFamMap

Allelic Variants