KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1XBCA_STU (PDB code: 1XBC, chain A)
Number of involved diseases in the family	105
Number of FGR related diseases	1

All kinase in this family FGR

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	FGR, JAK1, JAK3, LYN, PRKACG, SYK, TYK2	16	Link
	Prostate cancer	CHEK2, EGFR, EPHB2, FGFR1, FGFR2, PDGFRA, PDGFRB	42	Link
n/a	Measles	FYN, JAK1, JAK2, JAK3, TYK2	16	Link
	Leukemia	ABL1, ABL2, JAK2, KIT, PDGFRB	15	Link
	Lung cancer	ALK, EGFR, PTK2, ROS1	40	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, LYN, SRC	41	Link
n/a	Tuberculosis	JAK1, JAK2, SRC, SYK	21	Link
	Melanoma	EGFR, FGFR1, PDGFRA, PDGFRB	41	Link
n/a	Influenza A	JAK1, JAK2, PRKCA, TYK2	59	Link
n/a	Amoebiasis	PRKACG, PRKCA, PTK2	57	Link
n/a	Herpes simplex infection	JAK1, JAK2, TYK2	10	Link
n/a	Immunodeficiencies	JAK3, LCK, ZAP70	16	Link
n/a	Glioma	EGFR, PDGFRA, PDGFRB	41	Link
n/a	Toxoplasmosis	JAK1, JAK2, TYK2	10	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA	61	Link
	Neuroblastoma	ALK, NTRK2, NTRK3	10	Link
n/a	Hepatitis C	EGFR, JAK1, TYK2	40	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	13	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	12	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	12	Link
n/a	Prion diseases	FYN, PRKACG	10	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
n/a	Leishmaniasis	JAK1, JAK2	10	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	SCID	JAK3, LCK	16	Link
	Gastric cancer	EGFR, FGFR2	39	Link
n/a	Vibrio cholerae infection	PRKACG, PRKCA	55	Link
n/a	Choriocarcinoma	CSF1R, EGFR	43	Link
n/a	Shigellosis	ABL1, SRC	20	Link
n/a	Cervical cancer	EGFR, FGFR3	38	Link
n/a	Bladder cancer	EGFR, FGFR3	38	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
	Agammaglobulinemia	BTK	5	Link
n/a	Pituitary Dwarfism	BTK	5	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
	Apert syndrome	FGFR2	8	Link
	Scaphocephaly	FGFR2	8	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
n/a	Agammaglobulinemias	BTK	5	Link
	Craniosynostosis	FGFR2	8	Link
	Li-Fraumeni syndrome	CHEK2	5	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
n/a	Esophageal cancer	EGFR	38	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
	Adenocarcinoma of lung	EGFR	38	Link
	Trigonocephaly	FGFR1	9	Link
n/a	Oral cancer	EGFR	38	Link
n/a	Laryngeal cancer	EGFR	38	Link
	Kallmann syndrome	FGFR1	9	Link
	Breast cancer	CHEK2	5	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	13	Link
	Osteosarcoma	CHEK2	5	Link
n/a	Nevus	FGFR3	7	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	African trypanosomiasis	PRKCA	55	Link
n/a	Pituitary tumor	PRKCA	55	Link
n/a	Thyroid cancer	RET	11	Link
n/a	Cardiomyopathy	PRKACG	1	Link
n/a	Cocaine addiction	PRKACG	1	Link
n/a	Myasthenic syndrome	MUSK	5	Link
n/a	Alcoholism	NTRK2	9	Link
n/a	Obesity	NTRK2	9	Link
n/a	Hypereosinophilic syndrome	PDGFRA	10	Link
n/a	Renal agenesis and Renal adysplasia	RET	11	Link
	Hirschsprung disease	RET	11	Link
	Colon cancer	SRC	19	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	8	Link
	Selective T-cell defect	ZAP70	10	Link
	Renal agenesis	RET	11	Link
	Pheochromocytoma	RET	11	Link
n/a	Congenital central hypoventilation syndrome	RET	11	Link
	Central hypoventilation syndrome	RET	11	Link
n/a	Medullary thyroid carcinoma	RET	11	Link
	Multiple endocrine neoplasia	RET	11	Link
n/a	Congenital myasthenic syndrome	MUSK	5	Link
	Mastocytosis with associated hematologic disorder	KIT	12	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	CATSHL syndrome	FGFR3	7	Link
n/a	Achondroplasia	FGFR3	7	Link
	Colorectal cancer	FGFR3	7	Link
n/a	Leprechaunism	INSR	5	Link
	Rabson-Mendenhall syndrome	INSR	5	Link
	Thrombocythemia	JAK2	10	Link
	Piebaldism	KIT	12	Link
n/a	Germ cell tumors	KIT	12	Link
	Mast cell leukemia	KIT	12	Link
	Myelofibrosis	JAK2	10	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
	Diabetes mellitus	INSR	5	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link
	Lymphoproliferative syndrome	ITK	6	Link
	Polycythemia vera	JAK2	10	Link

BioXGEM.

KIDFamMap

Allelic Variants