Allelic Variants
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There are no related allelic variants
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Number of involved diseases in the family |
106 |
Number of FGR related diseases |
1 |
All kinase in this family
FGR
Allelic Variants |
Disease Description |
Involved kinases (This family) |
Inhibitor of Involved Kinases |
Search Disease |
n/a | Tuberculosis | AKT2, AKT3, CAMK2A, CAMK2D, CAMK2G, JAK2, MAPK10, MAPK12, MAPK8, PLK3, RAF1, SRC, SYK | 22 | Link | n/a | Epstein-Barr virus infection | AKT2, AKT3, CDC2, CDK2, CSNK2A2, FGR, GSK3B, JAK3, MAPK10, MAPK12, MAPK8, SYK | 19 | Link | n/a | Measles | AKT2, AKT3, CDK2, CDK6, CSNK2A2, FYN, GSK3B, JAK2, JAK3, PRKCQ | 18 | Link | n/a | Influenza A | AKT2, AKT3, GSK3B, JAK2, MAPK10, MAPK12, MAPK8, PRKCA, PRKCB, RAF1 | 61 | Link | | Prostate cancer | AKT2, AKT3, CDK2, CHEK2, FGFR2, GSK3B, PDPK1, RAF1 | 15 | Link | | Leukemia | ABL1, ABL2, AKT2, AKT3, CDK6, JAK2, PIM2, RAF1 | 13 | Link | n/a | Hepatitis C | AKT2, AKT3, GSK3B, MAPK10, MAPK12, MAPK8, RAF1 | 11 | Link | n/a | Salmonella infection | MAPK10, MAPK12, MAPK8, PKN1, PKN2, ROCK1, ROCK2 | 13 | Link | n/a | Shigellosis | ABL1, MAPK10, MAPK12, MAPK8, ROCK1, ROCK2, SRC | 22 | Link | n/a | Herpes simplex infection | CDC2, CDK2, CSNK2A2, JAK2, MAPK10, MAPK8 | 15 | Link | n/a | Toxoplasmosis | AKT2, AKT3, JAK2, MAPK10, MAPK12, MAPK8 | 11 | Link | n/a | Chagas disease | AKT2, AKT3, MAPK10, MAPK12, MAPK8 | 8 | Link | | Diabetes mellitus | AKT2, MAPK10, MAPK8, PRKCD, PRKCE | 15 | Link | n/a | Epithelial cell signaling in Helicobacter pylori infection | CSK, MAPK10, MAPK12, MAPK8, SRC | 21 | Link | n/a | Pathogenic Escherichia coli infection | ABL1, FYN, PRKCA, ROCK1, ROCK2 | 61 | Link | n/a | Alcoholism | CAMKK1, CAMKK2, NTRK2, RAF1 | 11 | Link | | Melanoma | AKT2, AKT3, CDK6, RAF1 | 8 | Link | | Lung cancer | AKT2, AKT3, CDK2, CDK6 | 12 | Link | | Neuroblastoma | NTRK1, NTRK2, NTRK3 | 15 | Link | n/a | Leishmaniasis | JAK2, MAPK12, PRKCB | 14 | Link | n/a | Viral myocarditis | ABL1, ABL2, FYN | 13 | Link | n/a | Pertussis | MAPK10, MAPK12, MAPK8 | 7 | Link | n/a | Bladder cancer | DAPK1, FGFR3 | 9 | Link | n/a | Immunodeficiencies | JAK3, ZAP70 | 16 | Link | n/a | Early infantile epileptic encephalopathy | CDKL5, MAPK10 | 6 | Link | n/a | Epileptic encephalopathy | CDKL5, MAPK10 | 6 | Link | n/a | Basal cell carcinoma | GSK3B, STK36 | 10 | Link | n/a | Thyroid cancer | NTRK1, RET | 18 | Link | | Colon cancer | AURKA, SRC | 19 | Link | | Mental retardation | CASK, DYRK1A | 7 | Link | n/a | African trypanosomiasis | PRKCA, PRKCB | 55 | Link | n/a | Amoebiasis | PRKCA, PRKCB | 55 | Link | | LADD syndrome | FGFR2, FGFR3 | 8 | Link | n/a | Vibrio cholerae infection | PRKCA, PRKCB | 55 | Link | n/a | Medullary thyroid carcinoma | NTRK1, RET | 18 | Link | | Crouzon syndrome | FGFR2, FGFR3 | 8 | Link | | Gastric cancer | FGFR2 | 8 | Link | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 8 | Link | | Pfeiffer syndrome | FGFR2 | 8 | Link | | Craniosynostosis | FGFR2 | 8 | Link | | Apert syndrome | FGFR2 | 8 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 8 | Link | | Jackson-Weiss syndrome | FGFR2 | 8 | Link | | Bent bone dysplasia syndrome | FGFR2 | 8 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 8 | Link | n/a | Prader-Willi and Angelman syndromes | CDKL5 | 1 | Link | n/a | Myotonic dystrophy | DMPK | 7 | Link | n/a | Maturity onset diabetes of the young | BLK | 8 | Link | | Hypoinsulinemic hypoglycemia | AKT2 | 7 | Link | | Ovarian cancer | AKT2 | 7 | Link | n/a | Familial partial lipodystrophy | AKT2 | 7 | Link | n/a | FG syndrome | CASK | 1 | Link | n/a | Saethre-Chotzen syndrome | FGFR2 | 8 | Link | | Osteosarcoma | CHEK2 | 5 | Link | | Breast cancer | CHEK2 | 5 | Link | | Li-Fraumeni syndrome | CHEK2 | 5 | Link | n/a | Cocaine addiction | CDK5 | 5 | Link | n/a | Angelman syndrome-like | CDKL5 | 1 | Link | n/a | Achondroplasia | FGFR3 | 7 | Link | | Scaphocephaly | FGFR2 | 8 | Link | n/a | Pituitary tumor | PRKCA | 55 | Link | n/a | Cerebral infarction | PRKCH | 12 | Link | n/a | Type I diabetes mellitus | PRKCQ | 8 | Link | | LEOPARD syndrome | RAF1 | 2 | Link | | Glycogen storage disease | PHKG2 | 9 | Link | n/a | Cirrhosis due to liver phosphorylase kinase deficiency | PHKG2 | 9 | Link | n/a | Amyotrophic lateral sclerosis | MAPK12 | 3 | Link | n/a | Insensitivity to pain | NTRK1 | 15 | Link | n/a | Obesity | NTRK2 | 9 | Link | n/a | Glycogen storage diseases | PHKG2 | 9 | Link | | Noonan syndrome | RAF1 | 2 | Link | n/a | Renal agenesis and Renal adysplasia | RET | 11 | Link | n/a | Transient erythroblastopenia of childhood | TEC | 2 | Link | | Venous malformations | TEK | 32 | Link | n/a | Rheumatoid arthritis | TEK | 32 | Link | | Selective T-cell defect | ZAP70 | 10 | Link | | Renal agenesis | RET | 11 | Link | | Pheochromocytoma | RET | 11 | Link | | Hirschsprung disease | RET | 11 | Link | n/a | Congenital central hypoventilation syndrome | RET | 11 | Link | | Central hypoventilation syndrome | RET | 11 | Link | | Multiple endocrine neoplasia | RET | 11 | Link | | REtinitis pigmentosa | MAK | 1 | Link | | SCID | JAK3 | 15 | Link | n/a | Hypochondroplasia | FGFR3 | 7 | Link | n/a | Muenke syndrome | FGFR3 | 7 | Link | n/a | Nevus | FGFR3 | 7 | Link | n/a | Spermatocytic seminoma | FGFR3 | 7 | Link | | Colorectal cancer | FGFR3 | 7 | Link | n/a | Cervical cancer | FGFR3 | 7 | Link | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 8 | Link | n/a | Multiple myeloma | FGFR3 | 7 | Link | n/a | FGFR3-related short limb skeletal dysplasias | FGFR3 | 7 | Link | n/a | CATSHL syndrome | FGFR3 | 7 | Link | n/a | Thanatophoric dysplasia | FGFR3 | 7 | Link | n/a | Cancer progression/metastasis | FGFR4 | 3 | Link | n/a | Budd-Chiari syndrome | JAK2 | 10 | Link | | Myelofibrosis | JAK2 | 10 | Link | n/a | Myeloproliferative disorder | JAK2 | 10 | Link | | Thrombocythemia | JAK2 | 10 | Link | | Polycythemia vera | JAK2 | 10 | Link | | Lymphoproliferative syndrome | ITK | 6 | Link | n/a | Prion diseases | FYN | 10 | Link | n/a | Congenital stationary night blindness | GRK1 | 4 | Link | n/a | Oguchi disease | GRK1 | 4 | Link | n/a | Endocrine-cerebroosteodysplasia | ICK | 2 | Link |
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