KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3BKBA_STU (PDB code: 3BKB, chain A)
Number of involved diseases in the family	138
Number of FGR related diseases	1

All kinase in this family FGR

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	AKT2, AKT3, CDC2, CDK2, CHUK, FGR, JAK1, JAK3, MAP3K7, MAPK12, PRKACA, PRKACB, PRKACG, PRKX, SYK, TYK2	18	Link
n/a	Measles	AKT2, AKT3, CDK2, CDK4, CDK6, CHUK, FYN, IRAK4, JAK1, JAK2, JAK3, MAP3K7, PRKCQ, TYK2	18	Link
	Prostate cancer	AKT2, AKT3, CDK2, CHUK, EGFR, EPHB2, FGFR1, FGFR2, IGF1R, INSRR, MAPK1, PDGFRA, PDGFRB, RAF1	45	Link
	Melanoma	AKT2, AKT3, CDK4, CDK6, EGFR, FGFR1, IGF1R, MAPK1, MET, PDGFRA, PDGFRB, RAF1	44	Link
	Leukemia	AKT2, AKT3, CDK4, CDK6, CHUK, JAK2, KIT, MAPK1, PDGFRB, RAF1, RPS6KB1, RPS6KB2	16	Link
n/a	Tuberculosis	AKT2, AKT3, IRAK4, JAK1, JAK2, MAPK1, MAPK12, RAF1, RIPK2, SRC, SYK	21	Link
n/a	Toxoplasmosis	AKT2, AKT3, CHUK, IRAK4, JAK1, JAK2, MAP3K7, MAPK1, MAPK12, TYK2	12	Link
	Lung cancer	AKT2, AKT3, ALK, CDK2, CDK4, CDK6, CHUK, EGFR, ROS1	43	Link
n/a	Hepatitis C	AKT2, AKT3, CHUK, EGFR, JAK1, MAPK1, MAPK12, RAF1, TYK2	41	Link
n/a	Influenza A	AKT2, AKT3, IRAK4, JAK1, JAK2, MAPK1, MAPK12, RAF1, TYK2	12	Link
n/a	Herpes simplex infection	CDC2, CDK2, CHUK, JAK1, JAK2, MAP3K7, TYK2	14	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CHUK, EGFR, MAPK12, MET, PAK1, SRC	42	Link
n/a	Leishmaniasis	IRAK4, JAK1, JAK2, MAP3K7, MAPK1, MAPK12	12	Link
n/a	Prion diseases	FYN, MAPK1, PRKACA, PRKACB, PRKACG, PRKX	11	Link
n/a	Chagas disease	AKT2, AKT3, CHUK, IRAK4, MAPK1, MAPK12	9	Link
n/a	Cocaine addiction	CDK5, PRKACA, PRKACB, PRKACG, PRKX	9	Link
n/a	Shigellosis	CHUK, MAPK1, MAPK12, RIPK2, SRC	19	Link
n/a	Alcoholism	MAPK1, NTRK2, PRKACA, RAF1	11	Link
n/a	Glioma	CDK4, EGFR, PDGFRA, PDGFRB	43	Link
n/a	Cardiomyopathy	PRKACA, PRKACB, PRKACG, PRKX	8	Link
	Diabetes mellitus	AKT2, INSR, MAPK1, PRKCD	15	Link
	Neuroblastoma	ALK, NTRK1, NTRK2, NTRK3	16	Link
n/a	Amoebiasis	PRKACA, PRKACB, PRKACG, PRKX	8	Link
n/a	Vibrio cholerae infection	PRKACA, PRKACB, PRKACG, PRKX	8	Link
n/a	Cervical cancer	CDK4, EGFR, FGFR3	40	Link
	Gastric cancer	EGFR, FGFR2, MET	39	Link
n/a	Bladder cancer	DAPK1, EGFR, FGFR3	39	Link
n/a	Pertussis	IRAK4, MAPK1, MAPK12	6	Link
n/a	Salmonella infection	MAPK1, MAPK12, PKN2	11	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	12	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	12	Link
n/a	Immunodeficiencies	JAK3, ZAP70	16	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
	Colon cancer	AURKA, SRC	19	Link
n/a	Choriocarcinoma	CSF1R, EGFR	43	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	Hemangioma	FLT4, KDR	54	Link
n/a	Medullary thyroid carcinoma	NTRK1, RET	18	Link
n/a	Amyotrophic lateral sclerosis	MAP3K5, MAPK12	6	Link
n/a	Thyroid cancer	NTRK1, RET	18	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	3	Link
n/a	Oral cancer	EGFR	38	Link
n/a	Esophageal cancer	EGFR	38	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	13	Link
n/a	Insensitivity to pain	NTRK1	15	Link
n/a	Non-syndromic X-linked mental retardation	PAK3	8	Link
n/a	Obesity	NTRK2	9	Link
n/a	Cocoon syndrome	CHUK	6	Link
n/a	Nephronophthisis	NEK8	1	Link
n/a	Laryngeal cancer	EGFR	38	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
	Apert syndrome	FGFR2	8	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
n/a	Short rib-polydactyly syndorme	NEK1	3	Link
	Kallmann syndrome	FGFR1	9	Link
	Adenocarcinoma of lung	EGFR	38	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
n/a	Nephronophthisis-medullary cystic kidney disease	NEK8	1	Link
	Trigonocephaly	FGFR1	9	Link
	Mental retardation	PAK3	8	Link
n/a	Malignant melanoma	CDK4	6	Link
	Renal agenesis	RET	11	Link
	Pheochromocytoma	RET	11	Link
	Multiple endocrine neoplasia	RET	11	Link
	Central hypoventilation syndrome	RET	11	Link
n/a	Popliteal pterygium syndrome	RIPK4	1	Link
n/a	Basal cell carcinoma	STK36	3	Link
n/a	Familial partial lipodystrophy	AKT2	7	Link
	Selective T-cell defect	ZAP70	10	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	8	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
n/a	Congenital central hypoventilation syndrome	RET	11	Link
	Hirschsprung disease	RET	11	Link
	Agammaglobulinemia	BTK	5	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
n/a	Type I diabetes mellitus	PRKCQ	8	Link
n/a	Hypereosinophilic syndrome	PDGFRA	10	Link
n/a	Pituitary Dwarfism	BTK	5	Link
n/a	Agammaglobulinemias	BTK	5	Link
n/a	Renal agenesis and Renal adysplasia	RET	11	Link
	Hypoinsulinemic hypoglycemia	AKT2	7	Link
	Noonan syndrome	RAF1	2	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
	LEOPARD syndrome	RAF1	2	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
	Craniosynostosis	FGFR2	8	Link
n/a	Invasive pneumococcal disease	IRAK4	4	Link
	IRAK4 deficiency	IRAK4	4	Link
	Lymphoproliferative syndrome	ITK	6	Link
	Polycythemia vera	JAK2	10	Link
n/a	Malaria	MET	8	Link
n/a	Autism suseptibility	MET	8	Link
	Insulin-like growth factor I	IGF1R	5	Link
n/a	Leprechaunism	INSR	5	Link
	Rabson-Mendenhall syndrome	INSR	5	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
	Myelofibrosis	JAK2	10	Link
	Mast cell leukemia	KIT	12	Link
	Mastocytosis with associated hematologic disorder	KIT	12	Link
	REtinitis pigmentosa	MAK	1	Link
n/a	46XY sex reversal 6	MAP3K1	1	Link
n/a	Germ cell tumors	KIT	12	Link
	Retinitis pigmentosa	MERTK	6	Link
n/a	Cholangiocarcinoma	MET	8	Link
	Thrombocythemia	JAK2	10	Link
	Renal cell carcinoma	MET	8	Link
	Piebaldism	KIT	12	Link
	SCID	JAK3	15	Link
n/a	Synovial sarcoma	IGF1R	5	Link
n/a	Malignant pleural mesothelioma	IGF1R	5	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	CATSHL syndrome	FGFR3	7	Link
n/a	Achondroplasia	FGFR3	7	Link
	Colorectal cancer	FGFR3	7	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
n/a	Myasthenic syndrome	MUSK	5	Link
n/a	Congenital myasthenic syndrome	MUSK	5	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
	Scaphocephaly	FGFR2	8	Link
n/a	Hypochondroplasia	FGFR3	7	Link
n/a	Muenke syndrome	FGFR3	7	Link
	Hepatocellular carcinoma	MET	8	Link
n/a	Pathogenic Escherichia coli infection	FYN	10	Link
n/a	Viral myocarditis	FYN	10	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link
n/a	Lymphedema	FLT4	17	Link
	Ovarian cancer	AKT2	7	Link
n/a	Nevus	FGFR3	7	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Lymphedemas	FLT4	17	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link

BioXGEM.

KIDFamMap

Allelic Variants