Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
86 |
| Number of FRK related diseases |
0 |
All kinase in this family
FRK
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| n/a | Measles | CDK2, CDK4, FYN, GSK3B,
IRAK4, JAK2, JAK3, MAP3K7,
PRKCQ | 62 | Link | | n/a | Epstein-Barr virus infection | CDK2, FGR, GSK3B, JAK3, LYN,
MAP2K3, MAP2K6, MAP3K7 | 38 | Link | | n/a | Influenza A | GSK3B, IRAK4, JAK2, MAP2K1,
MAP2K3, MAP2K6, PRKCA | 7 | Link | | Prostate cancer | CDK2, CHEK2, FGFR1, FGFR2,
GSK3B, MAP2K1 | 43 | Link | | Leukemia | ABL1, ABL2, CDK4, JAK2,
MAP2K1, RPS6KB1 | 56 | Link | | n/a | Pathogenic Escherichia coli infection | ABL1, FYN, PRKCA, ROCK1,
ROCK2 | 15 | Link | | n/a | Toxoplasmosis | IRAK4, JAK2, MAP2K3, MAP2K6,
MAP3K7 | 3 | Link | | Melanoma | CDK4, FGFR1, MAP2K1, MET | 53 | Link | | n/a | Salmonella infection | PKN1, PKN2, ROCK1, ROCK2 | 1 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | LYN, MET, PAK1, SRC | 131 | Link | | n/a | Shigellosis | ABL1, ROCK1, ROCK2, SRC | 129 | Link | | n/a | Tuberculosis | CAMK2A, IRAK4, JAK2, SRC | 129 | Link | | n/a | Herpes simplex infection | CDK2, JAK2, MAP3K7 | 32 | Link | | n/a | Leishmaniasis | IRAK4, JAK2, MAP3K7 | 3 | Link | | Mental retardation | CASK, PAK3, RPS6KA3 | 2 | Link | | n/a | Immunodeficiencies | JAK3, LCK, ZAP70 | 20 | Link | | n/a | Alcoholism | CAMKK2, MAP2K1, NTRK2 | 4 | Link | | n/a | Viral myocarditis | ABL1, ABL2, FYN | 14 | Link | | SCID | JAK3, LCK | 19 | Link | | n/a | Basal cell carcinoma | GSK3B, STK36 | 2 | Link | | n/a | Amyotrophic lateral sclerosis | MAP2K3, MAP2K6 | 1 | Link | | n/a | Non-syndromic X-linked mental retardation | PAK3, RPS6KA3 | 2 | Link | | n/a | Prion diseases | FYN, MAP2K1 | 6 | Link | | Diabetes mellitus | PRKCD, PRKCE | 11 | Link | | Pfeiffer syndrome | FGFR1, FGFR2 | 9 | Link | | Gastric cancer | FGFR2, MET | 4 | Link | | Lung cancer | CDK2, CDK4 | 48 | Link | | Jackson-Weiss syndrome | FGFR1, FGFR2 | 9 | Link | | Neuroblastoma | NTRK2, NTRK3 | 3 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 1 | Link | | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 1 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 1 | Link | | Bent bone dysplasia syndrome | FGFR2 | 1 | Link | | Apert syndrome | FGFR2 | 1 | Link | | Osteosarcoma | CHEK2 | 2 | Link | | Kallmann syndrome | FGFR1 | 8 | Link | | n/a | Glioma | CDK4 | 40 | Link | | n/a | Malignant melanoma | CDK4 | 40 | Link | | n/a | Cervical cancer | CDK4 | 40 | Link | | n/a | Maturity onset diabetes of the young | BLK | 3 | Link | | n/a | FG syndrome | CASK | 1 | Link | | Li-Fraumeni syndrome | CHEK2 | 2 | Link | | Breast cancer | CHEK2 | 2 | Link | | Osteoglophonic dysplasia | FGFR1 | 8 | Link | | Trigonocephaly | FGFR1 | 8 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 8 | Link | | n/a | Spondylometaepiphyseal dysplasia | DDR2 | 1 | Link | | Craniosynostosis | FGFR2 | 1 | Link | | n/a | Legionellosis | CLK1 | 1 | Link | | n/a | Hepatitis C | GSK3B | 1 | Link | | Crouzon syndrome | FGFR2 | 1 | Link | | n/a | Cirrhosis due to liver phosphorylase kinase deficiency | PHKG2 | 1 | Link | | Glycogen storage disease | PHKG2 | 1 | Link | | n/a | Glycogen storage diseases | PHKG2 | 1 | Link | | n/a | Obesity | NTRK2 | 2 | Link | | n/a | Autism suseptibility | MET | 3 | Link | | Hepatocellular carcinoma | MET | 3 | Link | | n/a | Short rib-polydactyly syndorme | NEK1 | 1 | Link | | n/a | Vibrio cholerae infection | PRKCA | 2 | Link | | n/a | African trypanosomiasis | PRKCA | 2 | Link | | Colon cancer | SRC | 129 | Link | | Selective T-cell defect | ZAP70 | 3 | Link | | n/a | Coffin-Lowry syndrome | RPS6KA3 | 1 | Link | | n/a | Type I diabetes mellitus | PRKCQ | 10 | Link | | n/a | Amoebiasis | PRKCA | 2 | Link | | n/a | Pituitary tumor | PRKCA | 2 | Link | | n/a | Cerebral infarction | PRKCH | 1 | Link | | n/a | Malaria | MET | 3 | Link | | n/a | Cholangiocarcinoma | MET | 3 | Link | | n/a | Chagas disease | IRAK4 | 2 | Link | | n/a | Invasive pneumococcal disease | IRAK4 | 2 | Link | | n/a | Pertussis | IRAK4 | 2 | Link | | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 1 | Link | | LADD syndrome | FGFR2 | 1 | Link | | n/a | Saethre-Chotzen syndrome | FGFR2 | 1 | Link | | Scaphocephaly | FGFR2 | 1 | Link | | IRAK4 deficiency | IRAK4 | 2 | Link | | Lymphoproliferative syndrome | ITK | 1 | Link | | n/a | Noonan syndrome and related disorders | MAP2K1 | 3 | Link | | Cardiofaciocutaneous syndrome | MAP2K1 | 3 | Link | | Renal cell carcinoma | MET | 3 | Link | | Thrombocythemia | JAK2 | 1 | Link | | n/a | Myeloproliferative disorder | JAK2 | 1 | Link | | Polycythemia vera | JAK2 | 1 | Link | | n/a | Budd-Chiari syndrome | JAK2 | 1 | Link | | Myelofibrosis | JAK2 | 1 | Link |
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