KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2VTTA_LZD (PDB code: 2VTT, chain A)
Number of involved diseases in the family	111
Number of GRK7 related diseases	0

All kinase in this family GRK7

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	AKT2, CDC2, CDK2, CHUK, CSNK2A1, CSNK2A2, EIF2AK2, FGR, GSK3B, JAK1, JAK3, LYN, MAP2K3, MAP2K6, MAP3K7, MAPK10, MAPK14, MAPK9	23	Link
n/a	Measles	AKT2, CDK2, CDK4, CDK6, CHUK, CSNK2A1, CSNK2A2, EIF2AK2, FYN, GSK3B, IRAK4, JAK1, JAK2, JAK3, MAP3K7, PRKCQ	25	Link
n/a	Influenza A	AKT2, EIF2AK2, GSK3B, IRAK4, JAK1, JAK2, MAP2K1, MAP2K3, MAP2K6, MAPK10, MAPK14, MAPK9, PRKCA	10	Link
n/a	Tuberculosis	AKT2, CAMK2A, CAMK2B, CAMK2D, IRAK4, JAK1, JAK2, MAPK10, MAPK14, MAPK9, SRC	6	Link
n/a	Toxoplasmosis	AKT2, CHUK, IRAK4, JAK1, JAK2, MAP2K3, MAP2K6, MAP3K7, MAPK10, MAPK14, MAPK9	6	Link
n/a	Herpes simplex infection	CDC2, CDK2, CHUK, CSNK2A1, CSNK2A2, EIF2AK2, JAK1, JAK2, MAP3K7, MAPK10, MAPK9	22	Link
	Leukemia	ABL1, ABL2, AKT2, CDK4, CDK6, CHUK, JAK2, MAP2K1, PIM2, RPS6KB1	8	Link
	Prostate cancer	AKT2, CDK2, CHEK2, CHUK, FGFR1, FGFR2, GSK3B, MAP2K1, PDPK1	28	Link
n/a	Shigellosis	ABL1, CHUK, MAPK10, MAPK14, MAPK9, ROCK1, ROCK2, SRC	5	Link
n/a	Hepatitis C	AKT2, CHUK, EIF2AK2, GSK3B, JAK1, MAPK10, MAPK14, MAPK9	5	Link
n/a	Salmonella infection	MAPK10, MAPK14, MAPK9, PKN1, PKN2, ROCK1, ROCK2	4	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CHUK, LYN, MAPK10, MAPK14, MAPK9, MET, SRC	5	Link
	Melanoma	AKT2, CDK4, CDK6, FGFR1, MAP2K1, MET	10	Link
n/a	Chagas disease	AKT2, CHUK, IRAK4, MAPK10, MAPK14, MAPK9	5	Link
n/a	Leishmaniasis	IRAK4, JAK1, JAK2, MAP3K7, MAPK14	6	Link
	Lung cancer	AKT2, CDK2, CDK4, CDK6, CHUK	20	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA, ROCK1, ROCK2	4	Link
n/a	Alcoholism	CAMKK1, CAMKK2, MAP2K1, NTRK2	7	Link
	Mental retardation	CASK, DYRK1A, PAK3, RPS6KA3	5	Link
n/a	Pertussis	IRAK4, MAPK10, MAPK14, MAPK9	4	Link
n/a	Immunodeficiencies	JAK3, LCK, ZAP70	5	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	4	Link
n/a	Amyotrophic lateral sclerosis	MAP2K3, MAP2K6, MAPK14	2	Link
	Diabetes mellitus	AKT2, MAPK10, MAPK9	2	Link
n/a	Prion diseases	FYN, MAP2K1	5	Link
n/a	Epileptic encephalopathy	CDKL5, MAPK10	2	Link
	Gastric cancer	FGFR2, MET	3	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	7	Link
n/a	Early infantile epileptic encephalopathy	CDKL5, MAPK10	2	Link
	Pfeiffer syndrome	FGFR1, FGFR2	7	Link
	LADD syndrome	FGFR2, FGFR3	4	Link
	Crouzon syndrome	FGFR2, FGFR3	4	Link
	Neuroblastoma	NTRK2, NTRK3	4	Link
n/a	Cervical cancer	CDK4, FGFR3	5	Link
n/a	Non-syndromic X-linked mental retardation	PAK3, RPS6KA3	4	Link
	Colon cancer	AURKA, SRC	5	Link
	SCID	JAK3, LCK	4	Link
n/a	Bladder cancer	DAPK1, FGFR3	4	Link
	Apert syndrome	FGFR2	3	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	3	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	1	Link
	Hypogonadotropic hypogonadism	FGFR1	7	Link
	Osteoglophonic dysplasia	FGFR1	7	Link
	Kallmann syndrome	FGFR1	7	Link
	Trigonocephaly	FGFR1	7	Link
n/a	Malignant melanoma	CDK4	2	Link
n/a	Legionellosis	CLK1	5	Link
n/a	FG syndrome	CASK	1	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	3	Link
n/a	Maturity onset diabetes of the young	BLK	4	Link
	Hypoinsulinemic hypoglycemia	AKT2	2	Link
	Ovarian cancer	AKT2	2	Link
n/a	Familial partial lipodystrophy	AKT2	2	Link
n/a	Glioma	CDK4	2	Link
n/a	Cocaine addiction	CDK5	3	Link
	Osteosarcoma	CHEK2	4	Link
n/a	Cocoon syndrome	CHUK	2	Link
	Breast cancer	CHEK2	4	Link
	Li-Fraumeni syndrome	CHEK2	4	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Saethre-Chotzen syndrome	FGFR2	3	Link
	Bent bone dysplasia syndrome	FGFR2	3	Link
n/a	Cholangiocarcinoma	MET	1	Link
n/a	Malaria	MET	1	Link
n/a	Autism suseptibility	MET	1	Link
	Hepatocellular carcinoma	MET	1	Link
	Renal cell carcinoma	MET	1	Link
	Cardiofaciocutaneous syndrome	MAP2K1	5	Link
n/a	Myeloproliferative disorder	JAK2	3	Link
	Thrombocythemia	JAK2	3	Link
	REtinitis pigmentosa	MAK	1	Link
n/a	Noonan syndrome and related disorders	MAP2K1	5	Link
n/a	Congenital myasthenic syndrome	MUSK	2	Link
n/a	Myasthenic syndrome	MUSK	2	Link
n/a	Pituitary tumor	PRKCA	1	Link
n/a	Type I diabetes mellitus	PRKCQ	4	Link
n/a	Coffin-Lowry syndrome	RPS6KA3	4	Link
	Selective T-cell defect	ZAP70	1	Link
n/a	Amoebiasis	PRKCA	1	Link
n/a	African trypanosomiasis	PRKCA	1	Link
n/a	Obesity	NTRK2	4	Link
n/a	Glycogen storage diseases	PHKG2	5	Link
n/a	Cirrhosis due to liver phosphorylase kinase deficiency	PHKG2	5	Link
n/a	Vibrio cholerae infection	PRKCA	1	Link
	Glycogen storage disease	PHKG2	5	Link
	Myelofibrosis	JAK2	3	Link
n/a	Budd-Chiari syndrome	JAK2	3	Link
n/a	CATSHL syndrome	FGFR3	4	Link
n/a	Achondroplasia	FGFR3	4	Link
	Colorectal cancer	FGFR3	4	Link
n/a	Hypochondroplasia	FGFR3	4	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	4	Link
n/a	Multiple myeloma	FGFR3	4	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	3	Link
	Craniosynostosis	FGFR2	3	Link
	Scaphocephaly	FGFR2	3	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	3	Link
n/a	Muenke syndrome	FGFR3	4	Link
n/a	Nevus	FGFR3	4	Link
n/a	Invasive pneumococcal disease	IRAK4	3	Link
	IRAK4 deficiency	IRAK4	3	Link
	Lymphoproliferative syndrome	ITK	4	Link
	Polycythemia vera	JAK2	3	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	3	Link
n/a	Basal cell carcinoma	GSK3B	2	Link
n/a	Spermatocytic seminoma	FGFR3	4	Link
n/a	Thanatophoric dysplasia	FGFR3	4	Link
n/a	Cancer progression/metastasis	FGFR4	1	Link
n/a	Oguchi disease	GRK1	2	Link
n/a	Congenital stationary night blindness	GRK1	2	Link

BioXGEM.

KIDFamMap

Allelic Variants