Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
65 |
| Number of INSR related diseases |
4 |
All kinase in this family
INSR
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| Lung cancer | ALK, EGFR, PTK2, ROS1 | 3 | Link | | n/a | Measles | FYN, JAK2, JAK3, MAP3K7 | 2 | Link | | Prostate cancer | EGFR, ERBB2, IGF1R, INSRR | 82 | Link | | n/a | Immunodeficiencies | JAK3, LCK, ZAP70 | 18 | Link | | n/a | Choriocarcinoma | CSF1R, EGFR, ERBB2 | 3 | Link | | n/a | Epstein-Barr virus infection | JAK3, MAP3K7 | 1 | Link | | SCID | JAK3, LCK | 17 | Link | | n/a | Leishmaniasis | JAK2, MAP3K7 | 1 | Link | | Adenocarcinoma of lung | EGFR, ERBB2 | 2 | Link | | n/a | Tuberculosis | JAK2, SRC | 10 | Link | | Leukemia | JAK2, KIT | 2 | Link | | n/a | Toxoplasmosis | JAK2, MAP3K7 | 1 | Link | | Melanoma | EGFR, IGF1R | 82 | Link | | n/a | Herpes simplex infection | JAK2, MAP3K7 | 1 | Link | | n/a | Cervical cancer | EGFR, ERBB2 | 2 | Link | | n/a | Bladder cancer | EGFR, ERBB2 | 2 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | EGFR, SRC | 11 | Link | | Gastric cancer | EGFR, ERBB2 | 2 | Link | | n/a | Lymphedema | FLT4 | 1 | Link | | n/a | Pathogenic Escherichia coli infection | FYN | 1 | Link | | Hemangioma | FLT4 | 1 | Link | | n/a | Prion diseases | FYN | 1 | Link | | Glioblastoma | ERBB2 | 1 | Link | | n/a | Lymphedemas | FLT4 | 1 | Link | | n/a | Pancreatic cancer | ERBB2 | 1 | Link | | n/a | Cholangiocarcinoma | ERBB2 | 1 | Link | | n/a | Esophageal cancer | EGFR | 2 | Link | | n/a | Oral cancer | EGFR | 2 | Link | | n/a | Leukoencephalopathy, diffuse hereditary, with spheroids | CSF1R | 1 | Link | | Neuroblastoma | ALK | 2 | Link | | n/a | Glioma | EGFR | 2 | Link | | n/a | Laryngeal cancer | EGFR | 2 | Link | | Breast cancer | ERBB2 | 1 | Link | | Ovarian cancer | ERBB2 | 1 | Link | | Endometrial Cancer | ERBB2 | 1 | Link | | n/a | Hepatitis C | EGFR | 2 | Link | | n/a | Leprechaunism | INSR | 5 | Link | | n/a | Viral myocarditis | FYN | 1 | Link | | n/a | Non-syndromic X-linked mental retardation | RPS6KA3 | 1 | Link | | n/a | Amoebiasis | PTK2 | 1 | Link | | Retinitis pigmentosa | MERTK | 1 | Link | | Mast cell leukemia | KIT | 1 | Link | | Mastocytosis with associated hematologic disorder | KIT | 1 | Link | | n/a | Coffin-Lowry syndrome | RPS6KA3 | 1 | Link | | Mental retardation | RPS6KA3 | 1 | Link | | Selective T-cell defect | ZAP70 | 1 | Link | | n/a | Rheumatoid arthritis | TEK | 8 | Link | | Venous malformations | TEK | 8 | Link | | n/a | Shigellosis | SRC | 9 | Link | | Colon cancer | SRC | 9 | Link | | n/a | Germ cell tumors | KIT | 1 | Link | | Gastrointestinal stromal tumor | KIT | 1 | Link | | Diabetes mellitus | INSR | 5 | Link | | Rabson-Mendenhall syndrome | INSR | 5 | Link | | Insulin-like growth factor I | IGF1R | 81 | Link | | n/a | Malignant pleural mesothelioma | IGF1R | 81 | Link | | n/a | Synovial sarcoma | IGF1R | 81 | Link | | Hyperinsulinemic hypoglycemia | INSR | 5 | Link | | Polycythemia vera | JAK2 | 1 | Link | | Thrombocythemia | JAK2 | 1 | Link | | Piebaldism | KIT | 1 | Link | | n/a | Myeloproliferative disorder | JAK2 | 1 | Link | | Myelofibrosis | JAK2 | 1 | Link | | n/a | Influenza A | JAK2 | 1 | Link | | n/a | Budd-Chiari syndrome | JAK2 | 1 | Link |
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