Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
75 |
| Number of LCK related diseases |
2 |
All kinase in this family
LCK
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| n/a | Influenza A | EIF2AK2, IRAK4, JAK2,
MAPK14, PRKCA, RAF1 | 30 | Link | | Prostate cancer | CDK2, EGFR, FGFR1, FGFR2,
PDGFRB, RAF1 | 51 | Link | | n/a | Measles | CDK2, EIF2AK2, FYN, IRAK4,
JAK2 | 4 | Link | | n/a | Tuberculosis | IRAK4, JAK2, MAPK14, RAF1,
SRC | 40 | Link | | n/a | Epstein-Barr virus infection | CDC2, CDK2, EIF2AK2, FGR,
MAPK14 | 44 | Link | | Melanoma | EGFR, FGFR1, PDGFRB, RAF1 | 49 | Link | | n/a | Hepatitis C | EGFR, EIF2AK2, MAPK14, RAF1 | 58 | Link | | n/a | Herpes simplex infection | CDC2, CDK2, EIF2AK2, JAK2 | 21 | Link | | Leukemia | JAK2, PDGFRB, RAF1 | 8 | Link | | Lung cancer | ALK, CDK2, EGFR | 34 | Link | | n/a | Toxoplasmosis | IRAK4, JAK2, MAPK14 | 26 | Link | | n/a | Leishmaniasis | IRAK4, JAK2, MAPK14 | 26 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | EGFR, MAPK14, SRC | 68 | Link | | n/a | Myeloproliferative disorder | JAK2, PDGFRB | 6 | Link | | n/a | Shigellosis | MAPK14, SRC | 36 | Link | | n/a | Pertussis | IRAK4, MAPK14 | 25 | Link | | n/a | Pathogenic Escherichia coli infection | FYN, PRKCA | 2 | Link | | Pfeiffer syndrome | FGFR1, FGFR2 | 16 | Link | | Colon cancer | AURKA, SRC | 19 | Link | | Neuroblastoma | ALK, NTRK3 | 2 | Link | | Jackson-Weiss syndrome | FGFR1, FGFR2 | 16 | Link | | Gastric cancer | EGFR, FGFR2 | 36 | Link | | n/a | Glioma | EGFR, PDGFRB | 37 | Link | | n/a | Chagas disease | IRAK4, MAPK14 | 25 | Link | | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 4 | Link | | Apert syndrome | FGFR2 | 4 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 4 | Link | | Bent bone dysplasia syndrome | FGFR2 | 4 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 4 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 12 | Link | | Kallmann syndrome | FGFR1 | 12 | Link | | n/a | Bladder cancer | EGFR | 32 | Link | | n/a | Esophageal cancer | EGFR | 32 | Link | | n/a | Oral cancer | EGFR | 32 | Link | | n/a | Cocaine addiction | CDK5 | 1 | Link | | n/a | Choriocarcinoma | EGFR | 32 | Link | | n/a | Cervical cancer | EGFR | 32 | Link | | Trigonocephaly | FGFR1 | 12 | Link | | Osteoglophonic dysplasia | FGFR1 | 12 | Link | | Craniosynostosis | FGFR2 | 4 | Link | | n/a | Laryngeal cancer | EGFR | 32 | Link | | Adenocarcinoma of lung | EGFR | 32 | Link | | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 4 | Link | | Crouzon syndrome | FGFR2 | 4 | Link | | Noonan syndrome | RAF1 | 2 | Link | | n/a | Thyroid cancer | RET | 1 | Link | | LEOPARD syndrome | RAF1 | 2 | Link | | n/a | Alcoholism | RAF1 | 2 | Link | | n/a | Amoebiasis | PRKCA | 1 | Link | | n/a | Pituitary tumor | PRKCA | 1 | Link | | n/a | Renal agenesis and Renal adysplasia | RET | 1 | Link | | Hirschsprung disease | RET | 1 | Link | | Pheochromocytoma | RET | 1 | Link | | Renal agenesis | RET | 1 | Link | | Multiple endocrine neoplasia | RET | 1 | Link | | n/a | Medullary thyroid carcinoma | RET | 1 | Link | | n/a | Congenital central hypoventilation syndrome | RET | 1 | Link | | Central hypoventilation syndrome | RET | 1 | Link | | n/a | African trypanosomiasis | PRKCA | 1 | Link | | n/a | Vibrio cholerae infection | PRKCA | 1 | Link | | n/a | Viral myocarditis | FYN | 1 | Link | | n/a | Invasive pneumococcal disease | IRAK4 | 1 | Link | | n/a | Prion diseases | FYN | 1 | Link | | Scaphocephaly | FGFR2 | 4 | Link | | LADD syndrome | FGFR2 | 4 | Link | | n/a | Saethre-Chotzen syndrome | FGFR2 | 4 | Link | | IRAK4 deficiency | IRAK4 | 1 | Link | | Polycythemia vera | JAK2 | 1 | Link | | n/a | Amyotrophic lateral sclerosis | MAPK14 | 24 | Link | | n/a | Salmonella infection | MAPK14 | 24 | Link | | SCID | LCK | 67 | Link | | n/a | Immunodeficiencies | LCK | 67 | Link | | n/a | Budd-Chiari syndrome | JAK2 | 1 | Link | | Myelofibrosis | JAK2 | 1 | Link | | Thrombocythemia | JAK2 | 1 | Link |
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