KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 3EQFA_KSA (PDB code: 3EQF, chain A)
Number of involved diseases in the family	57
Number of MAP2K1 related diseases	8

All kinase in this family MAP2K1

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Measles	CDK2, CDK4, CDK6, GSK3B, IRAK4, JAK2, JAK3, MAP3K7	18	Link
n/a	Influenza A	GSK3B, IRAK4, JAK2, MAP2K1, MAP2K2, MAP2K4, PRKCA	21	Link
n/a	Epstein-Barr virus infection	CDC2, CDK2, GSK3B, JAK3, MAP2K4, MAP3K7	18	Link
	Leukemia	ABL1, CDK4, CDK6, JAK2, MAP2K1, MAP2K2	5	Link
	Melanoma	CDK4, CDK6, MAP2K1, MAP2K2	5	Link
	Prostate cancer	CDK2, GSK3B, MAP2K1, MAP2K2	5	Link
n/a	Herpes simplex infection	CDC2, CDK2, JAK2, MAP3K7	4	Link
n/a	Leishmaniasis	IRAK4, JAK2, MAP3K7	3	Link
n/a	Toxoplasmosis	IRAK4, JAK2, MAP3K7	3	Link
	Lung cancer	CDK2, CDK4, CDK6	4	Link
n/a	Prion diseases	MAP2K1, MAP2K2	4	Link
n/a	Chagas disease	IRAK4, MAP2K4	3	Link
n/a	Noonan syndrome and related disorders	MAP2K1, MAP2K2	4	Link
n/a	Pathogenic Escherichia coli infection	ABL1, PRKCA	20	Link
n/a	Immunodeficiencies	JAK3, ZAP70	17	Link
n/a	Tuberculosis	IRAK4, JAK2	3	Link
	Cardiofaciocutaneous syndrome	MAP2K1, MAP2K2	4	Link
n/a	Pertussis	IRAK4	2	Link
n/a	Invasive pneumococcal disease	IRAK4	2	Link
n/a	Basal cell carcinoma	GSK3B	1	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link
n/a	Malignant melanoma	CDK4	3	Link
n/a	Cervical cancer	CDK4	3	Link
n/a	Viral myocarditis	ABL1	1	Link
n/a	Glioma	CDK4	3	Link
n/a	Congenital stationary night blindness	GRK1	2	Link
n/a	Shigellosis	ABL1	1	Link
	IRAK4 deficiency	IRAK4	2	Link
n/a	Hepatitis C	GSK3B	1	Link
n/a	Oguchi disease	GRK1	2	Link
n/a	Budd-Chiari syndrome	JAK2	3	Link
	Lymphoproliferative syndrome	ITK	3	Link
n/a	Congenital central hypoventilation syndrome	RET	4	Link
	Hirschsprung disease	RET	4	Link
n/a	Renal agenesis and Renal adysplasia	RET	4	Link
n/a	Thyroid cancer	RET	4	Link
	Central hypoventilation syndrome	RET	4	Link
n/a	Medullary thyroid carcinoma	RET	4	Link
	Selective T-cell defect	ZAP70	4	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
	Renal agenesis	RET	4	Link
	Multiple endocrine neoplasia	RET	4	Link
	Pheochromocytoma	RET	4	Link
	Diabetes mellitus	PRKCE	3	Link
n/a	Pituitary tumor	PRKCA	19	Link
	SCID	JAK3	17	Link
	Thrombocythemia	JAK2	3	Link
n/a	Myeloproliferative disorder	JAK2	3	Link
	Polycythemia vera	JAK2	3	Link
	Myelofibrosis	JAK2	3	Link
	REtinitis pigmentosa	MAK	2	Link
n/a	Alcoholism	MAP2K1	4	Link
n/a	Amoebiasis	PRKCA	19	Link
n/a	African trypanosomiasis	PRKCA	19	Link
n/a	Vibrio cholerae infection	PRKCA	19	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	MAP2K4	2	Link
n/a	Salmonella infection	PKN1	3	Link

BioXGEM.

KIDFamMap

Allelic Variants