Allelic Variants
|
|
There are no related allelic variants
|
|
| Number of involved diseases in the family |
111 |
| Number of MAP4K3 related diseases |
0 |
All kinase in this family
MAP4K3
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| Prostate cancer | CDK2, CHUK, FGFR1, FGFR2,
IGF1R, INSRR, PDGFRA, PDGFRB | 24 | Link | | n/a | Epstein-Barr virus infection | CDK2, CHUK, FGR, JAK3, LYN,
MAPK14, RIPK1 | 22 | Link | | Leukemia | ABL1, ABL2, CHUK, JAK2, KIT,
PDGFRB, RPS6KB1 | 3 | Link | | n/a | Measles | CDK2, CHUK, FYN, IRAK4,
JAK2, JAK3 | 2 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | CHUK, LYN, MAPK14, MET, SRC | 24 | Link | | Melanoma | FGFR1, IGF1R, MET, PDGFRA,
PDGFRB | 24 | Link | | Lung cancer | ALK, CDK2, CHUK, PTK2, ROS1 | 3 | Link | | Neuroblastoma | ALK, NTRK1, NTRK2, NTRK3 | 2 | Link | | n/a | Toxoplasmosis | CHUK, IRAK4, JAK2, MAPK14 | 21 | Link | | n/a | Shigellosis | ABL1, CHUK, MAPK14, SRC | 23 | Link | | n/a | Tuberculosis | IRAK4, JAK2, MAPK14, SRC | 23 | Link | | n/a | Leishmaniasis | IRAK4, JAK2, MAPK14 | 21 | Link | | n/a | Immunodeficiencies | JAK3, LCK, ZAP70 | 1 | Link | | n/a | Influenza A | IRAK4, JAK2, MAPK14 | 21 | Link | | n/a | Hepatitis C | CHUK, MAPK14, RIPK1 | 21 | Link | | n/a | Viral myocarditis | ABL1, ABL2, FYN | 1 | Link | | n/a | Herpes simplex infection | CDK2, CHUK, JAK2 | 2 | Link | | n/a | Chagas disease | CHUK, IRAK4, MAPK14 | 21 | Link | | Gastric cancer | FGFR2, MET | 2 | Link | | SCID | JAK3, LCK | 1 | Link | | n/a | Pertussis | IRAK4, MAPK14 | 21 | Link | | Jackson-Weiss syndrome | FGFR1, FGFR2 | 4 | Link | | Pfeiffer syndrome | FGFR1, FGFR2 | 4 | Link | | n/a | Salmonella infection | MAPK14, PKN1 | 21 | Link | | Crouzon syndrome | FGFR2, FGFR3 | 1 | Link | | n/a | Thyroid cancer | NTRK1, RET | 3 | Link | | n/a | Glioma | PDGFRA, PDGFRB | 22 | Link | | n/a | Cardiomyopathy | PRKAA1, PRKAA2 | 1 | Link | | n/a | Pathogenic Escherichia coli infection | ABL1, FYN | 1 | Link | | Hemangioma | FLT4, KDR | 23 | Link | | LADD syndrome | FGFR2, FGFR3 | 1 | Link | | n/a | Myeloproliferative disorder | JAK2, PDGFRB | 3 | Link | | n/a | Medullary thyroid carcinoma | NTRK1, RET | 3 | Link | | Gastrointestinal stromal tumor | KIT, PDGFRA | 20 | Link | | n/a | Cervical cancer | FGFR3 | 1 | Link | | n/a | Multiple myeloma | FGFR3 | 1 | Link | | n/a | Hypochondroplasia | FGFR3 | 1 | Link | | n/a | Muenke syndrome | FGFR3 | 1 | Link | | n/a | Nevus | FGFR3 | 1 | Link | | Colorectal cancer | FGFR3 | 1 | Link | | n/a | Achondroplasia | FGFR3 | 1 | Link | | n/a | Bladder cancer | FGFR3 | 1 | Link | | n/a | FGFR3-related short limb skeletal dysplasias | FGFR3 | 1 | Link | | n/a | CATSHL syndrome | FGFR3 | 1 | Link | | Apert syndrome | FGFR2 | 1 | Link | | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 1 | Link | | Osteoglophonic dysplasia | FGFR1 | 4 | Link | | Trigonocephaly | FGFR1 | 4 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 4 | Link | | n/a | Spondylometaepiphyseal dysplasia | DDR2 | 1 | Link | | n/a | Cocoon syndrome | CHUK | 1 | Link | | n/a | Choriocarcinoma | CSF1R | 13 | Link | | n/a | Leukoencephalopathy, diffuse hereditary, with spheroids | CSF1R | 13 | Link | | Kallmann syndrome | FGFR1 | 4 | Link | | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 1 | Link | | n/a | Saethre-Chotzen syndrome | FGFR2 | 1 | Link | | Scaphocephaly | FGFR2 | 1 | Link | | Craniosynostosis | FGFR2 | 1 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 1 | Link | | n/a | Spermatocytic seminoma | FGFR3 | 1 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 1 | Link | | Bent bone dysplasia syndrome | FGFR2 | 1 | Link | | n/a | Malignant pleural mesothelioma | IGF1R | 1 | Link | | n/a | Thanatophoric dysplasia | FGFR3 | 1 | Link | | n/a | Obesity | NTRK2 | 1 | Link | | n/a | Non-syndromic X-linked mental retardation | PAK3 | 1 | Link | | Mental retardation | PAK3 | 1 | Link | | n/a | Hypereosinophilic syndrome | PDGFRA | 20 | Link | | n/a | Alcoholism | NTRK2 | 1 | Link | | n/a | Insensitivity to pain | NTRK1 | 1 | Link | | n/a | Autism suseptibility | MET | 2 | Link | | Hepatocellular carcinoma | MET | 2 | Link | | n/a | Congenital myasthenic syndrome | MUSK | 1 | Link | | n/a | Myasthenic syndrome | MUSK | 1 | Link | | n/a | Amoebiasis | PTK2 | 1 | Link | | n/a | Renal agenesis and Renal adysplasia | RET | 3 | Link | | Colon cancer | SRC | 3 | Link | | Venous malformations | TEK | 1 | Link | | n/a | Rheumatoid arthritis | TEK | 1 | Link | | Selective T-cell defect | ZAP70 | 1 | Link | | Renal agenesis | RET | 3 | Link | | Pheochromocytoma | RET | 3 | Link | | Hirschsprung disease | RET | 3 | Link | | n/a | Congenital central hypoventilation syndrome | RET | 3 | Link | | Central hypoventilation syndrome | RET | 3 | Link | | Multiple endocrine neoplasia | RET | 3 | Link | | n/a | Malaria | MET | 2 | Link | | n/a | Cholangiocarcinoma | MET | 2 | Link | | Insulin-like growth factor I | IGF1R | 1 | Link | | n/a | Leprechaunism | INSR | 1 | Link | | Rabson-Mendenhall syndrome | INSR | 1 | Link | | Diabetes mellitus | INSR | 1 | Link | | n/a | Synovial sarcoma | IGF1R | 1 | Link | | n/a | Endocrine-cerebroosteodysplasia | ICK | 1 | Link | | n/a | Cancer progression/metastasis | FGFR4 | 1 | Link | | n/a | Lymphedemas | FLT4 | 1 | Link | | n/a | Lymphedema | FLT4 | 1 | Link | | n/a | Prion diseases | FYN | 1 | Link | | Hyperinsulinemic hypoglycemia | INSR | 1 | Link | | n/a | Invasive pneumococcal disease | IRAK4 | 1 | Link | | Mast cell leukemia | KIT | 1 | Link | | Mastocytosis with associated hematologic disorder | KIT | 1 | Link | | n/a | Amyotrophic lateral sclerosis | MAPK14 | 20 | Link | | Renal cell carcinoma | MET | 2 | Link | | n/a | Germ cell tumors | KIT | 1 | Link | | Piebaldism | KIT | 1 | Link | | IRAK4 deficiency | IRAK4 | 1 | Link | | Polycythemia vera | JAK2 | 1 | Link | | n/a | Budd-Chiari syndrome | JAK2 | 1 | Link | | Thrombocythemia | JAK2 | 1 | Link | | Myelofibrosis | JAK2 | 1 | Link |
|