KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 2GQGA_1N1 (PDB code: 2GQG, chain A)
Number of involved diseases in the family	117
Number of MAP4K3 related diseases	0

All kinase in this family MAP4K3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	BRAF, EGFR, EPHB2, ERBB2, FGFR1, FGFR2, MAP2K1, PDGFRA, PDGFRB	5	Link
	Leukemia	ABL1, ABL2, BRAF, JAK2, KIT, MAP2K1, PDGFRB, TGFBR1	7	Link
n/a	Epstein-Barr virus infection	FGR, JAK3, LYN, MAP3K7, MAPK14, SYK, TYK2	7	Link
	Melanoma	BRAF, EGFR, FGFR1, MAP2K1, PDGFRA, PDGFRB	4	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, LYN, MAPK14, SRC	10	Link
n/a	Measles	FYN, JAK2, JAK3, MAP3K7, TYK2	5	Link
n/a	Tuberculosis	JAK2, MAPK14, RIPK2, SRC, SYK	10	Link
n/a	Shigellosis	ABL1, MAPK14, RIPK2, SRC	10	Link
n/a	Toxoplasmosis	JAK2, MAP3K7, MAPK14, TYK2	4	Link
n/a	Influenza A	JAK2, MAP2K1, MAPK14, TYK2	4	Link
n/a	Hepatitis C	BRAF, EGFR, MAPK14, TYK2	4	Link
	Adenocarcinoma of lung	BRAF, EGFR, ERBB2	4	Link
n/a	Herpes simplex infection	JAK2, MAP3K7, TYK2	2	Link
	Gastric cancer	EGFR, ERBB2, FGFR2	4	Link
n/a	Glioma	EGFR, PDGFRA, PDGFRB	4	Link
n/a	Leishmaniasis	JAK2, MAP3K7, MAPK14	4	Link
n/a	Bladder cancer	EGFR, ERBB2, FGFR3	4	Link
n/a	Cervical cancer	EGFR, ERBB2, FGFR3	4	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	9	Link
n/a	Choriocarcinoma	CSF1R, EGFR, ERBB2	5	Link
	Crouzon syndrome	FGFR2, FGFR3	2	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN	9	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	2	Link
n/a	Immunodeficiencies	JAK3, LCK	29	Link
n/a	Prion diseases	FYN, MAP2K1	5	Link
	LADD syndrome	FGFR2, FGFR3	2	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	4	Link
	Colon cancer	AURKA, SRC	9	Link
n/a	Chagas disease	MAPK14, TGFBR1	4	Link
n/a	Alcoholism	BRAF, MAP2K1	2	Link
	SCID	JAK3, LCK	29	Link
	Pfeiffer syndrome	FGFR1, FGFR2	2	Link
n/a	Thyroid cancer	BRAF, RET	3	Link
n/a	Noonan syndrome and related disorders	BRAF, MAP2K1	2	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	4	Link
n/a	Pancreatic cancer	ACVR1B, ERBB2	3	Link
	Lung cancer	BRAF, EGFR	3	Link
	Colorectal cancer	BRAF, FGFR3	2	Link
	Cardiofaciocutaneous syndrome	BRAF, MAP2K1	2	Link
	Endometrial Cancer	ERBB2	3	Link
n/a	Laryngeal cancer	EGFR	3	Link
	Osteoglophonic dysplasia	FGFR1	2	Link
	Trigonocephaly	FGFR1	2	Link
	Glioblastoma	ERBB2	3	Link
	Hypogonadotropic hypogonadism	FGFR1	2	Link
n/a	Lethal congenital contractural syndrome	ERBB3	1	Link
n/a	Cholangiocarcinoma	ERBB2	3	Link
n/a	Type I diabetes mellitus	ERBB3	1	Link
	Breast cancer	ERBB2	3	Link
	Ovarian cancer	ERBB2	3	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
n/a	Esophageal cancer	EGFR	3	Link
n/a	Malignant melanoma	BRAF	2	Link
	LEOPARD syndrome	BRAF	2	Link
n/a	Chrondrodysplasia	BMPR1B	1	Link
	Brachydactyly	BMPR1B	1	Link
n/a	Juvenile polyposis syndrome	BMPR1A	1	Link
n/a	Polyposis	BMPR1A	1	Link
	Noonan syndrome	BRAF	2	Link
n/a	Agammaglobulinemias	BTK	5	Link
n/a	Spondylometaepiphyseal dysplasia	DDR2	4	Link
n/a	Oral cancer	EGFR	3	Link
	Fibrodysplasia ossificans progressiva	ACVR1	2	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	4	Link
n/a	Pituitary Dwarfism	BTK	5	Link
	Agammaglobulinemia	BTK	5	Link
n/a	Maturity onset diabetes of the young	BLK	5	Link
	Craniosynostosis	FGFR2	2	Link
	Kallmann syndrome	FGFR1	2	Link
n/a	Salmonella infection	MAPK14	4	Link
n/a	Pertussis	MAPK14	4	Link
n/a	Hypereosinophilic syndrome	PDGFRA	4	Link
n/a	Renal agenesis and Renal adysplasia	RET	3	Link
n/a	Amyotrophic lateral sclerosis	MAPK14	4	Link
	Mastocytosis with associated hematologic disorder	KIT	4	Link
	Hemangioma	KDR	2	Link
	Piebaldism	KIT	4	Link
n/a	Germ cell tumors	KIT	4	Link
	Mast cell leukemia	KIT	4	Link
	Hirschsprung disease	RET	3	Link
n/a	Congenital central hypoventilation syndrome	RET	3	Link
	Loeys-Dietz syndrome	TGFBR1	2	Link
n/a	Familial thoracic aortic aneurysm and dissection	TGFBR1	2	Link
	Multiple self-healing squamous epithelioma	TGFBR1	2	Link
n/a	Tyrosine kinase 2 deficiency	TYK2	1	Link
n/a	Transient erythroblastopenia of childhood	TEC	3	Link
n/a	Basal cell carcinoma	STK36	2	Link
	Central hypoventilation syndrome	RET	3	Link
n/a	Medullary thyroid carcinoma	RET	3	Link
	Multiple endocrine neoplasia	RET	3	Link
	Renal agenesis	RET	3	Link
	Pheochromocytoma	RET	3	Link
	Thrombocythemia	JAK2	2	Link
	Myelofibrosis	JAK2	2	Link
	Scaphocephaly	FGFR2	2	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	2	Link
n/a	Multiple myeloma	FGFR3	1	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	1	Link
n/a	Saethre-Chotzen syndrome	FGFR2	2	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	2	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	2	Link
	Apert syndrome	FGFR2	2	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	2	Link
	Bent bone dysplasia syndrome	FGFR2	2	Link
n/a	CATSHL syndrome	FGFR3	1	Link
n/a	Achondroplasia	FGFR3	1	Link
	Diabetes mellitus	INSR	1	Link
	Hyperinsulinemic hypoglycemia	INSR	1	Link
	Polycythemia vera	JAK2	2	Link
n/a	Budd-Chiari syndrome	JAK2	2	Link
	Rabson-Mendenhall syndrome	INSR	1	Link
n/a	Leprechaunism	INSR	1	Link
n/a	Hypochondroplasia	FGFR3	1	Link
n/a	Muenke syndrome	FGFR3	1	Link
n/a	Nevus	FGFR3	1	Link
n/a	Thanatophoric dysplasia	FGFR3	1	Link
n/a	Spermatocytic seminoma	FGFR3	1	Link

BioXGEM.

KIDFamMap

Allelic Variants