Allelic Variants

There are no related allelic variants
Related diseases of KIF 2FO0A_P16 (PDB code: 2FO0, chain A)
Number of involved diseases in the family 123
Number of MAP4K4 related diseases 0
All kinase in this family  MAP4K4
Allelic
Variants
Disease Description Involved kinases
(This family)
Inhibitor of
Involved Kinases
Search
Disease
Prostate cancerBRAF, EGFR, EPHB2, FGFR1,
FGFR2, IGF1R, MAP2K1,
PDGFRA, PDGFRB
53Link
n/aEpstein-Barr virus infectionFGR, JAK1, JAK3, LYN,
MAPK14, RIPK1, SYK, TYK2
15Link
LeukemiaABL1, ABL2, BRAF, JAK2, KIT,
MAP2K1, PDGFRB, TGFBR1
63Link
MelanomaBRAF, EGFR, FGFR1, IGF1R,
MAP2K1, MET, PDGFRA, PDGFRB
53Link
n/aTuberculosisJAK1, JAK2, MAPK14, PLK3,
RIPK2, SRC, SYK
62Link
n/aEpithelial cell signaling in Helicobacter pylori infectionCSK, EGFR, LYN, MAPK14, MET,
SRC
62Link
n/aHepatitis CBRAF, EGFR, JAK1, MAPK14,
RIPK1, TYK2
33Link
n/aMeaslesFYN, JAK1, JAK2, JAK3, TYK21Link
n/aInfluenza AJAK1, JAK2, MAP2K1, MAPK14,
TYK2
15Link
n/aShigellosisABL1, MAPK14, RIPK2, SRC67Link
n/aToxoplasmosisJAK1, JAK2, MAPK14, TYK215Link
n/aViral myocarditisABL1, ABL2, FYN21Link
Gastric cancerEGFR, FGFR2, MET23Link
n/aHerpes simplex infectionJAK1, JAK2, TYK21Link
n/aLeishmaniasisJAK1, JAK2, MAPK1415Link
n/aGliomaEGFR, PDGFRA, PDGFRB51Link
n/aImmunodeficienciesJAK3, LCK8Link
LADD syndromeFGFR2, FGFR35Link
Gastrointestinal stromal tumorKIT, PDGFRA8Link
n/aMyeloproliferative disorderJAK2, PDGFRB50Link
Crouzon syndromeFGFR2, FGFR35Link
HemangiomaFLT4, KDR1Link
Pfeiffer syndromeFGFR1, FGFR252Link
n/aChoriocarcinomaCSF1R, EGFR23Link
Jackson-Weiss syndromeFGFR1, FGFR252Link
n/aPrion diseasesFYN, MAP2K11Link
n/aBladder cancerEGFR, FGFR324Link
n/aCervical cancerEGFR, FGFR324Link
SCIDJAK3, LCK8Link
Lung cancerBRAF, EGFR23Link
Cardiofaciocutaneous syndromeBRAF, MAP2K11Link
Adenocarcinoma of lungBRAF, EGFR23Link
n/aAlcoholismBRAF, MAP2K11Link
n/aThyroid cancerBRAF, RET1Link
n/aNoonan syndrome and related disordersBRAF, MAP2K11Link
Colorectal cancerBRAF, FGFR35Link
n/aChagas diseaseMAPK14, TGFBR115Link
n/aPathogenic Escherichia coli infectionABL1, FYN21Link
Osteoglophonic dysplasiaFGFR152Link
n/aJuvenile polyposis syndromeBMPR1A1Link
Kallmann syndromeFGFR152Link
Apert syndromeFGFR21Link
TrigonocephalyFGFR152Link
n/aMaturity onset diabetes of the youngBLK1Link
CraniosynostosisFGFR21Link
Craniofacial-skeletal-dermatologic dysplasiaFGFR21Link
n/aAntley-Bixler syndrome without genital anomalies or disordered steroidogenesisFGFR21Link
Fibrodysplasia ossificans progressivaACVR11Link
Beare-Stevenson cutis gyrata syndromeFGFR21Link
n/aPancreatic cancerACVR1B1Link
Bent bone dysplasia syndromeFGFR21Link
Hypogonadotropic hypogonadismFGFR152Link
n/aChrondrodysplasiaBMPR1B1Link
n/aPolyposisBMPR1A1Link
n/aPituitary DwarfismBTK1Link
n/aAgammaglobulinemiasBTK1Link
n/aOral cancerEGFR23Link
n/aSpondylometaepiphyseal dysplasiaDDR21Link
n/aLeukoencephalopathy, diffuse hereditary, with spheroidsCSF1R1Link
AgammaglobulinemiaBTK1Link
n/aEsophageal cancerEGFR23Link
Noonan syndromeBRAF1Link
BrachydactylyBMPR1B1Link
n/aLethal congenital contractural syndromeERBB31Link
n/aAgammaglobulinemia and isolated hormone deficiencyBTK1Link
n/aType I diabetes mellitusERBB31Link
LEOPARD syndromeBRAF1Link
n/aMalignant melanomaBRAF1Link
n/aLaryngeal cancerEGFR23Link
n/aAchondroplasiaFGFR35Link
n/aSaethre-Chotzen syndromeFGFR21Link
n/aHypereosinophilic syndromePDGFRA1Link
n/aRenal agenesis and Renal adysplasiaRET1Link
Hirschsprung diseaseRET1Link
n/aCongenital central hypoventilation syndromeRET1Link
NeuroblastomaNTRK31Link
n/aShort rib-polydactyly syndormeNEK11Link
Renal cell carcinomaMET1Link
n/aCholangiocarcinomaMET1Link
n/aMalariaMET1Link
Hepatocellular carcinomaMET1Link
n/aAutism suseptibilityMET1Link
Central hypoventilation syndromeRET1Link
n/aMedullary thyroid carcinomaRET1Link
n/aRheumatoid arthritisTEK1Link
Loeys-Dietz syndromeTGFBR11Link
n/aFamilial thoracic aortic aneurysm and dissectionTGFBR11Link
n/aTyrosine kinase 2 deficiencyTYK21Link
Multiple self-healing squamous epitheliomaTGFBR11Link
Venous malformationsTEK1Link
n/aTransient erythroblastopenia of childhoodTEC1Link
Multiple endocrine neoplasiaRET1Link
PheochromocytomaRET1Link
Renal agenesisRET1Link
n/aBasal cell carcinomaSTK361Link
Colon cancerSRC61Link
n/aPertussisMAPK1415Link
n/aSalmonella infectionMAPK1415Link
n/aNevusFGFR35Link
n/aSpermatocytic seminomaFGFR35Link
n/aThanatophoric dysplasiaFGFR35Link
n/aCancer progression/metastasisFGFR41Link
n/aMuenke syndromeFGFR35Link
n/aHypochondroplasiaFGFR35Link
ScaphocephalyFGFR21Link
n/aScaphocephaly and Axenfeld-Rieger anomalyFGFR21Link
n/aMultiple myelomaFGFR35Link
n/aCATSHL syndromeFGFR35Link
n/aFGFR3-related short limb skeletal dysplasiasFGFR35Link
n/aLymphedemasFLT41Link
n/aLymphedemaFLT41Link
PiebaldismKIT8Link
n/aGerm cell tumorsKIT8Link
Mast cell leukemiaKIT8Link
n/aAmyotrophic lateral sclerosisMAPK1415Link
Mastocytosis with associated hematologic disorderKIT8Link
ThrombocythemiaJAK21Link
MyelofibrosisJAK21Link
n/aMalignant pleural mesotheliomaIGF1R1Link
n/aSynovial sarcomaIGF1R1Link
Insulin-like growth factor IIGF1R1Link
n/aBudd-Chiari syndromeJAK21Link
Polycythemia veraJAK21Link