Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
67 |
| Number of PDPK1 related diseases |
1 |
All kinase in this family
PDPK1
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| Prostate cancer | AKT2, CDK2, CHEK2, EGFR,
FGFR2, GSK3B, PDPK1 | 5 | Link | | n/a | Epstein-Barr virus infection | AKT2, CDK2, CSNK2A1,
EIF2AK2, GSK3B, MAPK10,
MAPK12 | 3 | Link | | n/a | Hepatitis C | AKT2, EGFR, EIF2AK2, GSK3B,
MAPK10, MAPK12 | 2 | Link | | n/a | Measles | AKT2, CDK2, CSNK2A1,
EIF2AK2, GSK3B, IRAK4 | 3 | Link | | n/a | Influenza A | AKT2, EIF2AK2, GSK3B, IRAK4,
MAPK10, MAPK12 | 2 | Link | | n/a | Tuberculosis | AKT2, IRAK4, MAPK10, MAPK12 | 1 | Link | | n/a | Toxoplasmosis | AKT2, IRAK4, MAPK10, MAPK12 | 1 | Link | | n/a | Chagas disease | AKT2, IRAK4, MAPK10, MAPK12 | 1 | Link | | n/a | Herpes simplex infection | CDK2, CSNK2A1, EIF2AK2,
MAPK10 | 2 | Link | | n/a | Pertussis | IRAK4, MAPK10, MAPK12 | 1 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | EGFR, MAPK10, MAPK12 | 1 | Link | | Lung cancer | AKT2, CDK2, EGFR | 2 | Link | | Melanoma | AKT2, EGFR, STK11 | 1 | Link | | Leukemia | ABL1, AKT2, PIM1 | 4 | Link | | n/a | Shigellosis | ABL1, MAPK10, MAPK12 | 3 | Link | | n/a | Bladder cancer | DAPK1, EGFR | 2 | Link | | Gastric cancer | EGFR, FGFR2 | 3 | Link | | n/a | Salmonella infection | MAPK10, MAPK12 | 1 | Link | | n/a | Leishmaniasis | IRAK4, MAPK12 | 1 | Link | | Diabetes mellitus | AKT2, MAPK10 | 1 | Link | | n/a | Oral cancer | EGFR | 1 | Link | | n/a | Esophageal cancer | EGFR | 1 | Link | | n/a | Choriocarcinoma | EGFR | 1 | Link | | n/a | Cervical cancer | EGFR | 1 | Link | | n/a | Glioma | EGFR | 1 | Link | | n/a | Laryngeal cancer | EGFR | 1 | Link | | Hypoinsulinemic hypoglycemia | AKT2 | 1 | Link | | Osteosarcoma | CHEK2 | 1 | Link | | n/a | Viral myocarditis | ABL1 | 2 | Link | | n/a | Pathogenic Escherichia coli infection | ABL1 | 2 | Link | | Ovarian cancer | AKT2 | 1 | Link | | n/a | Familial partial lipodystrophy | AKT2 | 1 | Link | | Breast cancer | CHEK2 | 1 | Link | | Li-Fraumeni syndrome | CHEK2 | 1 | Link | | Colon cancer | AURKA | 3 | Link | | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 2 | Link | | Adenocarcinoma of lung | EGFR | 1 | Link | | Hirschsprung disease | RET | 1 | Link | | n/a | Congenital central hypoventilation syndrome | RET | 1 | Link | | n/a | Renal agenesis and Renal adysplasia | RET | 1 | Link | | n/a | Thyroid cancer | RET | 1 | Link | | n/a | Epileptic encephalopathy | MAPK10 | 1 | Link | | n/a | Amyotrophic lateral sclerosis | MAPK12 | 1 | Link | | Central hypoventilation syndrome | RET | 1 | Link | | n/a | Medullary thyroid carcinoma | RET | 1 | Link | | n/a | Peutz-Jeghers syndrome | STK11 | 1 | Link | | n/a | Testicular tumor | STK11 | 1 | Link | | n/a | Pancreatic cancer | STK11 | 1 | Link | | Renal agenesis | RET | 1 | Link | | Multiple endocrine neoplasia | RET | 1 | Link | | Pheochromocytoma | RET | 1 | Link | | n/a | Early infantile epileptic encephalopathy | MAPK10 | 1 | Link | | IRAK4 deficiency | IRAK4 | 1 | Link | | Craniosynostosis | FGFR2 | 2 | Link | | Crouzon syndrome | FGFR2 | 2 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 2 | Link | | Bent bone dysplasia syndrome | FGFR2 | 2 | Link | | Apert syndrome | FGFR2 | 2 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 2 | Link | | Jackson-Weiss syndrome | FGFR2 | 2 | Link | | LADD syndrome | FGFR2 | 2 | Link | | n/a | Basal cell carcinoma | GSK3B | 2 | Link | | n/a | Invasive pneumococcal disease | IRAK4 | 1 | Link | | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 2 | Link | | Scaphocephaly | FGFR2 | 2 | Link | | Pfeiffer syndrome | FGFR2 | 2 | Link | | n/a | Saethre-Chotzen syndrome | FGFR2 | 2 | Link |
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