KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1NVQA_UCN (PDB code: 1NVQ, chain A)
Number of involved diseases in the family	79
Number of PLK3 related diseases	1

All kinase in this family PLK3

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
n/a	Epstein-Barr virus infection	AKT1, AKT2, AKT3, CDC2, CDK2, CHUK, CSNK2A1, CSNK2A2, EIF2AK2, EIF2AK4, GSK3B, JAK1, LYN, MAPK10, MAPK12, MAPK13, MAPK14, PRKACA, PRKACB, PRKACG, PRKX, TBK1	15	Link
n/a	Measles	AKT1, AKT2, AKT3, CDK2, CDK4, CDK6, CHUK, CSNK2A1, CSNK2A2, EIF2AK2, EIF2AK4, FYN, GSK3B, IKBKE, IRAK4, JAK1, PRKCQ, TBK1	14	Link
n/a	Influenza A	AKT1, AKT2, AKT3, EIF2AK2, EIF2AK4, GSK3B, IKBKE, IRAK4, JAK1, MAPK1, MAPK10, MAPK12, MAPK13, MAPK14, PRKCA, PRKCB, TBK1	56	Link
n/a	Tuberculosis	AKT1, AKT2, AKT3, CAMK2A, CAMK2B, CAMK2D, CAMK2G, IRAK4, JAK1, MAPK1, MAPK10, MAPK12, MAPK13, MAPK14, PLK3, SRC	20	Link
n/a	Hepatitis C	AKT1, AKT2, AKT3, CHUK, EIF2AK2, EIF2AK4, GSK3B, IKBKE, JAK1, MAPK1, MAPK10, MAPK12, MAPK13, MAPK14, TBK1	13	Link
n/a	Herpes simplex infection	CDC2, CDK2, CHUK, CSNK2A1, CSNK2A2, EIF2AK2, EIF2AK4, IKBKE, JAK1, MAPK10, TBK1	14	Link
	Leukemia	AKT1, AKT2, AKT3, CDK4, CDK6, CHUK, MAPK1, PIM1, PIM2, RPS6KB1, RPS6KB2	13	Link
n/a	Toxoplasmosis	AKT1, AKT2, AKT3, CHUK, IRAK4, JAK1, MAPK1, MAPK10, MAPK12, MAPK13, MAPK14	11	Link
n/a	Chagas disease	AKT1, AKT2, AKT3, CHUK, IRAK4, MAPK1, MAPK10, MAPK12, MAPK13, MAPK14	9	Link
n/a	Shigellosis	CHUK, MAPK1, MAPK10, MAPK12, MAPK13, MAPK14, ROCK1, ROCK2, SRC	19	Link
	Prostate cancer	AKT1, AKT2, AKT3, CDK2, CHEK2, CHUK, GSK3B, MAPK1, PDPK1	15	Link
n/a	Salmonella infection	MAPK1, MAPK10, MAPK12, MAPK13, MAPK14, PKN1, PKN2, ROCK1, ROCK2	12	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CHUK, LYN, MAPK10, MAPK12, MAPK13, MAPK14, PAK1, SRC	21	Link
	Lung cancer	AKT1, AKT2, AKT3, CDK2, CDK4, CDK6, CHUK	11	Link
n/a	Leishmaniasis	IRAK4, JAK1, MAPK1, MAPK12, MAPK13, MAPK14, PRKCB	12	Link
	Melanoma	AKT1, AKT2, AKT3, CDK4, CDK6, MAPK1, STK11	9	Link
n/a	Pertussis	IRAK4, MAPK1, MAPK10, MAPK12, MAPK13, MAPK14	9	Link
n/a	Vibrio cholerae infection	PRKACA, PRKACB, PRKACG, PRKCA, PRKCB, PRKX	53	Link
n/a	Prion diseases	FYN, MAPK1, PRKACA, PRKACB, PRKACG, PRKX	11	Link
	Diabetes mellitus	AKT2, MAPK1, MAPK10, PRKCD, PRKCE, PRKCZ	12	Link
n/a	Amoebiasis	PRKACA, PRKACB, PRKACG, PRKCA, PRKCB, PRKX	53	Link
n/a	Cocaine addiction	CDK5, PRKACA, PRKACB, PRKACG, PRKX	8	Link
n/a	Alcoholism	CAMKK1, CAMKK2, MAPK1, NTRK2, PRKACA	11	Link
n/a	Pathogenic Escherichia coli infection	FYN, PRKCA, ROCK1, ROCK2	55	Link
n/a	Cardiomyopathy	PRKACA, PRKACB, PRKACG, PRKX	8	Link
n/a	Amyotrophic lateral sclerosis	MAP3K5, MAPK12, MAPK13, MAPK14	6	Link
	Mental retardation	CASK, PAK3, RPS6KA3	9	Link
	Neuroblastoma	NTRK1, NTRK2, NTRK3	14	Link
n/a	African trypanosomiasis	PRKCA, PRKCB	50	Link
n/a	Epileptic encephalopathy	CDKL5, MAPK10	6	Link
	Breast cancer	AKT1, CHEK2	8	Link
n/a	Basal cell carcinoma	GSK3B, STK36	9	Link
n/a	Early infantile epileptic encephalopathy	CDKL5, MAPK10	6	Link
n/a	Non-syndromic X-linked mental retardation	PAK3, RPS6KA3	9	Link
	Ovarian cancer	AKT1, AKT2	7	Link
	Colon cancer	AURKA, SRC	19	Link
	Colorectal cancer	AKT1	7	Link
	Hypoinsulinemic hypoglycemia	AKT2	7	Link
n/a	Prader-Willi and Angelman syndromes	CDKL5	1	Link
n/a	Schizophrenia	AKT1	7	Link
n/a	Glioma	CDK4	5	Link
n/a	Malignant melanoma	CDK4	5	Link
n/a	FG syndrome	CASK	1	Link
n/a	Familial partial lipodystrophy	AKT2	7	Link
n/a	Proteus syndrome	AKT1	7	Link
n/a	Cervical cancer	CDK4	5	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
n/a	Bladder cancer	DAPK1	8	Link
n/a	Angelman syndrome-like	CDKL5	1	Link
n/a	Glycogen storage diseases	PHKG2	8	Link
n/a	Cirrhosis due to liver phosphorylase kinase deficiency	PHKG2	8	Link
n/a	Obesity	NTRK2	8	Link
n/a	Medullary thyroid carcinoma	NTRK1	14	Link
n/a	Thyroid cancer	NTRK1	14	Link
n/a	Insensitivity to pain	NTRK1	14	Link
	Glycogen storage disease	PHKG2	8	Link
n/a	Pituitary tumor	PRKCA	50	Link
n/a	Peutz-Jeghers syndrome	STK11	6	Link
n/a	Testicular tumor	STK11	6	Link
n/a	Pancreatic cancer	STK11	6	Link
n/a	Coffin-Lowry syndrome	RPS6KA3	7	Link
n/a	Cerebral infarction	PRKCH	10	Link
n/a	Type I diabetes mellitus	PRKCQ	8	Link
n/a	Nephronophthisis	NEK8	1	Link
n/a	Nephronophthisis-medullary cystic kidney disease	NEK8	1	Link
n/a	Myotonic dystrophy	DMPK	7	Link
n/a	Viral myocarditis	FYN	10	Link
n/a	PTEN hamartoma tumor syndrome	AKT1	7	Link
n/a	Cocoon syndrome	CHUK	6	Link
	Li-Fraumeni syndrome	CHEK2	5	Link
	Osteosarcoma	CHEK2	5	Link
n/a	Congenital stationary night blindness	GRK1	4	Link
n/a	Oguchi disease	GRK1	4	Link
n/a	46XY sex reversal 6	MAP3K1	1	Link
n/a	Short rib-polydactyly syndorme	NEK1	3	Link
	REtinitis pigmentosa	MAK	1	Link
	IRAK4 deficiency	IRAK4	4	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link
n/a	Invasive pneumococcal disease	IRAK4	4	Link

BioXGEM.

KIDFamMap

Allelic Variants