Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
63 |
| Number of ROS1 related diseases |
1 |
All kinase in this family
ROS1
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| n/a | Measles | CDK2, FYN, JAK1, JAK2, JAK3,
MAP3K7 | 10 | Link | | Lung cancer | ALK, BRAF, CDK2, ROS1 | 6 | Link | | Prostate cancer | BRAF, CDK2, FGFR2, PDPK1 | 6 | Link | | n/a | Herpes simplex infection | CDK2, JAK1, JAK2, MAP3K7 | 10 | Link | | n/a | Epstein-Barr virus infection | CDK2, JAK1, JAK3, MAP3K7 | 6 | Link | | n/a | Toxoplasmosis | JAK1, JAK2, MAP3K7 | 7 | Link | | n/a | Leishmaniasis | JAK1, JAK2, MAP3K7 | 7 | Link | | Neuroblastoma | ALK, NTRK2, NTRK3 | 1 | Link | | n/a | Tuberculosis | JAK1, JAK2, RIPK2 | 7 | Link | | n/a | Influenza A | JAK1, JAK2, PRKCA | 7 | Link | | n/a | Thyroid cancer | BRAF, RET | 2 | Link | | n/a | Pathogenic Escherichia coli infection | FYN, PRKCA | 1 | Link | | n/a | Hepatitis C | BRAF, JAK1 | 3 | Link | | n/a | Alcoholism | BRAF, NTRK2 | 2 | Link | | Leukemia | BRAF, JAK2 | 8 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 1 | Link | | Bent bone dysplasia syndrome | FGFR2 | 1 | Link | | Apert syndrome | FGFR2 | 1 | Link | | Crouzon syndrome | FGFR2 | 1 | Link | | Craniosynostosis | FGFR2 | 1 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 1 | Link | | Gastric cancer | FGFR2 | 1 | Link | | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 1 | Link | | Cardiofaciocutaneous syndrome | BRAF | 1 | Link | | Adenocarcinoma of lung | BRAF | 1 | Link | | Melanoma | BRAF | 1 | Link | | n/a | Malignant melanoma | BRAF | 1 | Link | | Colorectal cancer | BRAF | 1 | Link | | LEOPARD syndrome | BRAF | 1 | Link | | n/a | Noonan syndrome and related disorders | BRAF | 1 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | CSK | 1 | Link | | Jackson-Weiss syndrome | FGFR2 | 1 | Link | | Noonan syndrome | BRAF | 1 | Link | | Colon cancer | AURKA | 1 | Link | | n/a | Saethre-Chotzen syndrome | FGFR2 | 1 | Link | | LADD syndrome | FGFR2 | 1 | Link | | Hirschsprung disease | RET | 1 | Link | | n/a | Renal agenesis and Renal adysplasia | RET | 1 | Link | | n/a | Pituitary tumor | PRKCA | 1 | Link | | n/a | African trypanosomiasis | PRKCA | 1 | Link | | n/a | Amoebiasis | PRKCA | 1 | Link | | n/a | Congenital central hypoventilation syndrome | RET | 1 | Link | | Central hypoventilation syndrome | RET | 1 | Link | | n/a | Shigellosis | RIPK2 | 1 | Link | | Renal agenesis | RET | 1 | Link | | Pheochromocytoma | RET | 1 | Link | | n/a | Medullary thyroid carcinoma | RET | 1 | Link | | Multiple endocrine neoplasia | RET | 1 | Link | | n/a | Vibrio cholerae infection | PRKCA | 1 | Link | | n/a | Salmonella infection | PKN1 | 1 | Link | | n/a | Viral myocarditis | FYN | 1 | Link | | n/a | Prion diseases | FYN | 1 | Link | | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 1 | Link | | Pfeiffer syndrome | FGFR2 | 1 | Link | | Scaphocephaly | FGFR2 | 1 | Link | | Polycythemia vera | JAK2 | 7 | Link | | n/a | Budd-Chiari syndrome | JAK2 | 7 | Link | | SCID | JAK3 | 3 | Link | | n/a | Obesity | NTRK2 | 1 | Link | | n/a | Immunodeficiencies | JAK3 | 3 | Link | | Thrombocythemia | JAK2 | 7 | Link | | Myelofibrosis | JAK2 | 7 | Link | | n/a | Myeloproliferative disorder | JAK2 | 7 | Link |
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