KIDFamMap

Allelic Variants
There are no related allelic variants

Related diseases of KIF 1YVJA_4ST (PDB code: 1YVJ, chain A)
Number of involved diseases in the family	126
Number of TEC related diseases	1

All kinase in this family TEC

Allelic Variants	Disease Description	Involved kinases (This family)	Inhibitor of Involved Kinases	Search Disease
	Prostate cancer	AKT2, AKT3, CDK2, EGFR, ERBB2, FGFR1, FGFR2, GSK3B, MAP2K1, PDGFRA, PDGFRB, PDPK1, RAF1	44	Link
	Leukemia	ABL1, ABL2, AKT2, AKT3, JAK2, KIT, MAP2K1, PDGFRB, RAF1, RPS6KB1	16	Link
n/a	Epstein-Barr virus infection	AKT2, AKT3, CDC2, CDK2, FGR, GSK3B, JAK1, JAK3, MAP3K7, SYK	16	Link
n/a	Measles	AKT2, AKT3, CDK2, FYN, GSK3B, JAK1, JAK2, JAK3, MAP3K7, PRKCQ	16	Link
n/a	Influenza A	AKT2, AKT3, GSK3B, JAK1, JAK2, MAP2K1, PRKCA, PRKCB, RAF1	59	Link
	Melanoma	AKT2, AKT3, EGFR, FGFR1, MAP2K1, MET, PDGFRA, PDGFRB, RAF1	41	Link
n/a	Tuberculosis	AKT2, AKT3, JAK1, JAK2, RAF1, RIPK2, SRC, SYK	20	Link
n/a	Hepatitis C	AKT2, AKT3, EGFR, GSK3B, JAK1, RAF1	39	Link
	Lung cancer	AKT2, AKT3, ALK, CDK2, EGFR, ROS1	42	Link
n/a	Herpes simplex infection	CDC2, CDK2, JAK1, JAK2, MAP3K7	14	Link
n/a	Toxoplasmosis	AKT2, AKT3, JAK1, JAK2, MAP3K7	10	Link
n/a	Epithelial cell signaling in Helicobacter pylori infection	CSK, EGFR, MET, SRC	40	Link
n/a	Leishmaniasis	JAK1, JAK2, MAP3K7, PRKCB	13	Link
n/a	Alcoholism	CAMKK2, MAP2K1, NTRK2, RAF1	12	Link
	Gastric cancer	EGFR, ERBB2, FGFR2, MET	38	Link
n/a	Shigellosis	ABL1, RIPK2, SRC	19	Link
n/a	Pathogenic Escherichia coli infection	ABL1, FYN, PRKCA	60	Link
n/a	Choriocarcinoma	CSF1R, EGFR, ERBB2	39	Link
n/a	Cervical cancer	EGFR, ERBB2, FGFR3	37	Link
n/a	Glioma	EGFR, PDGFRA, PDGFRB	40	Link
	Neuroblastoma	ALK, NTRK2, NTRK3	10	Link
n/a	Viral myocarditis	ABL1, ABL2, FYN	13	Link
n/a	Bladder cancer	EGFR, ERBB2, FGFR3	37	Link
n/a	Immunodeficiencies	JAK3, ZAP70	14	Link
	Gastrointestinal stromal tumor	KIT, PDGFRA	12	Link
	Pfeiffer syndrome	FGFR1, FGFR2	9	Link
	Adenocarcinoma of lung	EGFR, ERBB2	37	Link
n/a	Prion diseases	FYN, MAP2K1	11	Link
n/a	Vibrio cholerae infection	PRKCA, PRKCB	54	Link
	Jackson-Weiss syndrome	FGFR1, FGFR2	9	Link
	Crouzon syndrome	FGFR2, FGFR3	8	Link
	Diabetes mellitus	AKT2, INSR	8	Link
n/a	Chagas disease	AKT2, AKT3	7	Link
	Ovarian cancer	AKT2, ERBB2	7	Link
	LADD syndrome	FGFR2, FGFR3	8	Link
	Colon cancer	AURKA, SRC	18	Link
n/a	Salmonella infection	PKN1, PKN2	11	Link
n/a	Amoebiasis	PRKCA, PRKCB	54	Link
n/a	Cholangiocarcinoma	ERBB2, MET	8	Link
n/a	Myeloproliferative disorder	JAK2, PDGFRB	12	Link
n/a	African trypanosomiasis	PRKCA, PRKCB	54	Link
	Trigonocephaly	FGFR1	9	Link
	Craniofacial-skeletal-dermatologic dysplasia	FGFR2	8	Link
	Kallmann syndrome	FGFR1	9	Link
	Osteoglophonic dysplasia	FGFR1	9	Link
	Craniosynostosis	FGFR2	8	Link
	Bent bone dysplasia syndrome	FGFR2	8	Link
	Beare-Stevenson cutis gyrata syndrome	FGFR2	8	Link
n/a	Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis	FGFR2	8	Link
	Apert syndrome	FGFR2	8	Link
n/a	Oral cancer	EGFR	37	Link
	Hypogonadotropic hypogonadism	FGFR1	9	Link
n/a	Pituitary Dwarfism	BTK	5	Link
	Agammaglobulinemia	BTK	5	Link
n/a	Agammaglobulinemias	BTK	5	Link
n/a	Maturity onset diabetes of the young	BLK	8	Link
n/a	Familial partial lipodystrophy	AKT2	7	Link
	Hypoinsulinemic hypoglycemia	AKT2	7	Link
n/a	Agammaglobulinemia and isolated hormone deficiency	BTK	5	Link
n/a	Leukoencephalopathy, diffuse hereditary, with spheroids	CSF1R	10	Link
	Breast cancer	ERBB2	2	Link
	Glioblastoma	ERBB2	2	Link
	Endometrial Cancer	ERBB2	2	Link
n/a	Pancreatic cancer	ERBB2	2	Link
n/a	Saethre-Chotzen syndrome	FGFR2	8	Link
n/a	Esophageal cancer	EGFR	37	Link
n/a	Laryngeal cancer	EGFR	37	Link
n/a	CATSHL syndrome	FGFR3	7	Link
	Scaphocephaly	FGFR2	8	Link
n/a	Hypereosinophilic syndrome	PDGFRA	10	Link
n/a	Pituitary tumor	PRKCA	54	Link
n/a	Cerebral infarction	PRKCH	11	Link
	LEOPARD syndrome	RAF1	2	Link
n/a	Type I diabetes mellitus	PRKCQ	8	Link
n/a	Obesity	NTRK2	9	Link
n/a	Myasthenic syndrome	MUSK	5	Link
	Renal cell carcinoma	MET	8	Link
n/a	Malaria	MET	8	Link
n/a	Autism suseptibility	MET	8	Link
n/a	Congenital myasthenic syndrome	MUSK	5	Link
	Hepatocellular carcinoma	MET	8	Link
	Noonan syndrome	RAF1	2	Link
n/a	Thyroid cancer	RET	9	Link
n/a	Popliteal pterygium syndrome	RIPK4	1	Link
n/a	Transient erythroblastopenia of childhood	TEC	2	Link
	Venous malformations	TEK	32	Link
	Selective T-cell defect	ZAP70	10	Link
n/a	Rheumatoid arthritis	TEK	32	Link
	Renal agenesis	RET	9	Link
	Pheochromocytoma	RET	9	Link
	Hirschsprung disease	RET	9	Link
n/a	Renal agenesis and Renal adysplasia	RET	9	Link
n/a	Congenital central hypoventilation syndrome	RET	9	Link
	Central hypoventilation syndrome	RET	9	Link
	Multiple endocrine neoplasia	RET	9	Link
n/a	Medullary thyroid carcinoma	RET	9	Link
	Cardiofaciocutaneous syndrome	MAP2K1	4	Link
n/a	Noonan syndrome and related disorders	MAP2K1	4	Link
n/a	Spermatocytic seminoma	FGFR3	7	Link
n/a	Thanatophoric dysplasia	FGFR3	7	Link
n/a	Cancer progression/metastasis	FGFR4	3	Link
n/a	Oguchi disease	GRK1	4	Link
n/a	Congenital stationary night blindness	GRK1	4	Link
n/a	Nevus	FGFR3	7	Link
n/a	Muenke syndrome	FGFR3	7	Link
n/a	Multiple myeloma	FGFR3	7	Link
n/a	Scaphocephaly and Axenfeld-Rieger anomaly	FGFR2	8	Link
n/a	FGFR3-related short limb skeletal dysplasias	FGFR3	7	Link
n/a	Achondroplasia	FGFR3	7	Link
n/a	Hypochondroplasia	FGFR3	7	Link
	Colorectal cancer	FGFR3	7	Link
n/a	Basal cell carcinoma	GSK3B	10	Link
n/a	Endocrine-cerebroosteodysplasia	ICK	2	Link
	SCID	JAK3	13	Link
	Piebaldism	KIT	12	Link
n/a	Germ cell tumors	KIT	12	Link
	Mastocytosis with associated hematologic disorder	KIT	12	Link
	Mast cell leukemia	KIT	12	Link
	Thrombocythemia	JAK2	10	Link
	Myelofibrosis	JAK2	10	Link
	Rabson-Mendenhall syndrome	INSR	5	Link
n/a	Leprechaunism	INSR	5	Link
	Hyperinsulinemic hypoglycemia	INSR	5	Link
	Lymphoproliferative syndrome	ITK	6	Link
n/a	Budd-Chiari syndrome	JAK2	10	Link
	Polycythemia vera	JAK2	10	Link

BioXGEM.

KIDFamMap

Allelic Variants