Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
101 |
| Number of TEC related diseases |
1 |
All kinase in this family
TEC
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| Prostate cancer | EGFR, EPHB2, FGFR1, FGFR2,
IGF1R, INSRR | 5 | Link | | Lung cancer | ALK, EGFR, PTK2, ROS1 | 3 | Link | | Neuroblastoma | ALK, NTRK1, NTRK2, NTRK3 | 2 | Link | | Melanoma | EGFR, FGFR1, IGF1R | 5 | Link | | n/a | Hepatitis C | EGFR, RIPK1, TYK2 | 3 | Link | | n/a | Bladder cancer | EGFR, FGFR3 | 3 | Link | | Gastric cancer | EGFR, FGFR2 | 3 | Link | | n/a | Cervical cancer | EGFR, FGFR3 | 3 | Link | | n/a | Medullary thyroid carcinoma | NTRK1, RET | 2 | Link | | n/a | Toxoplasmosis | JAK2, TYK2 | 2 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | EGFR, SRC | 4 | Link | | n/a | Thyroid cancer | NTRK1, RET | 2 | Link | | Crouzon syndrome | FGFR2, FGFR3 | 1 | Link | | LADD syndrome | FGFR2, FGFR3 | 1 | Link | | n/a | Influenza A | JAK2, TYK2 | 2 | Link | | n/a | Measles | JAK2, TYK2 | 2 | Link | | n/a | Shigellosis | ABL1, SRC | 8 | Link | | n/a | Tuberculosis | JAK2, SRC | 2 | Link | | Leukemia | ABL1, JAK2 | 7 | Link | | n/a | Herpes simplex infection | JAK2, TYK2 | 2 | Link | | Hemangioma | FLT4, KDR | 3 | Link | | Pfeiffer syndrome | FGFR1, FGFR2 | 2 | Link | | Jackson-Weiss syndrome | FGFR1, FGFR2 | 2 | Link | | n/a | Epstein-Barr virus infection | RIPK1, TYK2 | 2 | Link | | Apert syndrome | FGFR2 | 1 | Link | | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 1 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 1 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 1 | Link | | n/a | Multiple myeloma | FGFR3 | 1 | Link | | n/a | FGFR3-related short limb skeletal dysplasias | FGFR3 | 1 | Link | | n/a | CATSHL syndrome | FGFR3 | 1 | Link | | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 1 | Link | | Scaphocephaly | FGFR2 | 1 | Link | | Bent bone dysplasia syndrome | FGFR2 | 1 | Link | | Craniosynostosis | FGFR2 | 1 | Link | | n/a | Saethre-Chotzen syndrome | FGFR2 | 1 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 2 | Link | | Kallmann syndrome | FGFR1 | 2 | Link | | Agammaglobulinemia | BTK | 1 | Link | | n/a | Agammaglobulinemia and isolated hormone deficiency | BTK | 1 | Link | | n/a | Pituitary Dwarfism | BTK | 1 | Link | | n/a | Agammaglobulinemias | BTK | 1 | Link | | n/a | Pathogenic Escherichia coli infection | ABL1 | 7 | Link | | n/a | Viral myocarditis | ABL1 | 7 | Link | | n/a | Maturity onset diabetes of the young | BLK | 3 | Link | | n/a | Spondylometaepiphyseal dysplasia | DDR2 | 4 | Link | | n/a | Oral cancer | EGFR | 3 | Link | | n/a | Achondroplasia | FGFR3 | 1 | Link | | Osteoglophonic dysplasia | FGFR1 | 2 | Link | | Trigonocephaly | FGFR1 | 2 | Link | | Adenocarcinoma of lung | EGFR | 3 | Link | | n/a | Laryngeal cancer | EGFR | 3 | Link | | n/a | Esophageal cancer | EGFR | 3 | Link | | n/a | Choriocarcinoma | EGFR | 3 | Link | | n/a | Glioma | EGFR | 3 | Link | | n/a | Spermatocytic seminoma | FGFR3 | 1 | Link | | Colorectal cancer | FGFR3 | 1 | Link | | n/a | Renal agenesis and Renal adysplasia | RET | 1 | Link | | Hirschsprung disease | RET | 1 | Link | | n/a | Congenital central hypoventilation syndrome | RET | 1 | Link | | n/a | Amoebiasis | PTK2 | 1 | Link | | n/a | Obesity | NTRK2 | 1 | Link | | n/a | Congenital myasthenic syndrome | MUSK | 1 | Link | | n/a | Myasthenic syndrome | MUSK | 1 | Link | | n/a | Insensitivity to pain | NTRK1 | 2 | Link | | n/a | Alcoholism | NTRK2 | 1 | Link | | Central hypoventilation syndrome | RET | 1 | Link | | Multiple endocrine neoplasia | RET | 1 | Link | | n/a | Transient erythroblastopenia of childhood | TEC | 1 | Link | | Venous malformations | TEK | 1 | Link | | n/a | Rheumatoid arthritis | TEK | 1 | Link | | n/a | Tyrosine kinase 2 deficiency | TYK2 | 2 | Link | | Colon cancer | SRC | 2 | Link | | Mental retardation | RPS6KA3 | 2 | Link | | Pheochromocytoma | RET | 1 | Link | | Renal agenesis | RET | 1 | Link | | n/a | Non-syndromic X-linked mental retardation | RPS6KA3 | 2 | Link | | n/a | Coffin-Lowry syndrome | RPS6KA3 | 2 | Link | | Retinitis pigmentosa | MERTK | 1 | Link | | SCID | LCK | 6 | Link | | n/a | Malignant pleural mesothelioma | IGF1R | 2 | Link | | n/a | Synovial sarcoma | IGF1R | 2 | Link | | Insulin-like growth factor I | IGF1R | 2 | Link | | n/a | Lymphedema | FLT4 | 2 | Link | | n/a | Lymphedemas | FLT4 | 2 | Link | | n/a | Hypochondroplasia | FGFR3 | 1 | Link | | n/a | Muenke syndrome | FGFR3 | 1 | Link | | n/a | Nevus | FGFR3 | 1 | Link | | n/a | Thanatophoric dysplasia | FGFR3 | 1 | Link | | n/a | Leprechaunism | INSR | 1 | Link | | Rabson-Mendenhall syndrome | INSR | 1 | Link | | Myelofibrosis | JAK2 | 1 | Link | | n/a | Myeloproliferative disorder | JAK2 | 1 | Link | | Thrombocythemia | JAK2 | 1 | Link | | n/a | Immunodeficiencies | LCK | 6 | Link | | n/a | Budd-Chiari syndrome | JAK2 | 1 | Link | | n/a | Leishmaniasis | JAK2 | 1 | Link | | Diabetes mellitus | INSR | 1 | Link | | Hyperinsulinemic hypoglycemia | INSR | 1 | Link | | Lymphoproliferative syndrome | ITK | 18 | Link | | Polycythemia vera | JAK2 | 1 | Link |
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