Summary of query kinase
Query kinase CLK2 (P49760)
Kinase group CMGC
Number of inhibitors 127
Index Target Inhibitor Inhibitor 2D Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) POC Source Link
0 CLK2 CHEMBL1436585 BD50342892 n/a 1055 320 n/a n/a BindingDB BindingDB
1 CLK2 CHEMBL1612677 BD50342905 n/a 1209 n/a n/a n/a BindingDB BindingDB
2 CLK2 CHEMBL1435542 BD50342910 n/a 1327 380 n/a n/a BindingDB BindingDB
3 CLK2 CHEMBL1724489 BD50342911 n/a 1361 n/a n/a n/a BindingDB BindingDB
4 CLK2 CHEMBL1604618 BD50342913 n/a 1648 n/a n/a n/a BindingDB BindingDB
5 CLK2 CHEMBL1591577 BD50342926 n/a 173 n/a n/a n/a BindingDB BindingDB
6 CLK2 CHEMBL1552755 BD50342915 n/a 1810 n/a n/a n/a BindingDB BindingDB
7 CLK2 CHEMBL1474834 BD50342916 n/a 186 59 n/a n/a BindingDB BindingDB
8 CLK2 CHEMBL567331 BD50302986 n/a 1902 680 n/a n/a BindingDB BindingDB
9 CLK2 CHEMBL1704879 BD50342919 n/a 195 n/a n/a n/a BindingDB BindingDB
10 CLK2 CHEMBL1396654 BD50342891 n/a 2163 n/a n/a n/a BindingDB BindingDB
11 CLK2 CHEMBL1515868 BD50342894 n/a 2219 n/a n/a n/a BindingDB BindingDB
12 CLK2 CHEMBL1476499 BD50342918 n/a 2725 n/a n/a n/a BindingDB BindingDB
13 CLK2 CHEMBL1725513 BD50342893 n/a 301 n/a n/a n/a BindingDB BindingDB
14 CLK2 CHEMBL1437638 BD50342912 n/a 3118 n/a n/a n/a BindingDB BindingDB
15 CLK2 CHEMBL1397614 BD50342906 n/a 3331 n/a n/a n/a BindingDB BindingDB
16 CLK2 CHEMBL1407164 BD50342908 n/a 3594 n/a n/a n/a BindingDB BindingDB
17 CLK2 CHEMBL1705549 BD50342921 n/a 414 n/a n/a n/a BindingDB BindingDB
18 CLK2 CHEMBL1515144 BD50342927 n/a 447 n/a n/a n/a BindingDB BindingDB
19 CLK2 CHEMBL1354134 BD50342890 n/a 486 n/a n/a n/a BindingDB BindingDB
20 CLK2 CHEMBL1551169 BD50342896 n/a 584 n/a n/a n/a BindingDB BindingDB
21 CLK2 CHEMBL1396483 BD50342897 n/a 589 n/a n/a n/a BindingDB BindingDB
22 CLK2 CHEMBL1329627 BD50342917 n/a 6181 n/a n/a n/a BindingDB BindingDB
23 CLK2 CHEMBL1473127 BD50342900 n/a 651 n/a n/a n/a BindingDB BindingDB
24 CLK2 CHEMBL1374544 BD50342901 n/a 692 n/a n/a n/a BindingDB BindingDB
25 CLK2 CHEMBL1357975 BD50342903 n/a 801 n/a n/a n/a BindingDB BindingDB
26 CLK2 CHEMBL1770624 BD50342898 n/a 8480 n/a n/a n/a BindingDB BindingDB
27 CLK2 CHEMBL1535925 BD50342902 n/a 8510 n/a n/a n/a BindingDB BindingDB
28 CLK2 CHEMBL566900 BD50302984 n/a 877 n/a n/a n/a BindingDB BindingDB
29 CLK2 CHEMBL1734733 BD50342899 n/a 882 n/a n/a n/a BindingDB BindingDB
30 CLK2 CHEMBL1476609 BD50342895 n/a 889 n/a n/a n/a BindingDB BindingDB
31 CLK2 CHEMBL1318637 BD50342907 n/a 962 n/a n/a n/a BindingDB BindingDB
32 CLK2 A_674563 A_674563 n/a n/a 0.51 n/a n/a NB2011DRx NB2011DRx
33 CLK2 CHEMBL526901 BD50273635 n/a n/a 10 n/a n/a BindingDB BindingDB
34 CLK2 CHEMBL1082152 BD50312990 n/a n/a 10 n/a n/a BindingDB BindingDB
35 CLK2 PP_242 PP_242 n/a n/a 1000 n/a n/a NB2011DRx NB2011DRx
36 CLK2 BMS-387072 BD00005931 n/a n/a 1100 n/a n/a BindingDB BindingDB
37 CLK2 BMS_387032 BMS_387032 n/a n/a 1100 n/a n/a NB2008 NB2008
38 CLK2 BMS_387032 BMS_387032 n/a n/a 1100 n/a n/a NB2011DRx NB2011DRx
39 CLK2 Staurosporine BD00002579 n/a n/a 12 n/a n/a BindingDB BindingDB
40 CLK2 FLAVOPIRIDOL BD50088605 n/a n/a 1400 n/a n/a BindingDB BindingDB
41 CLK2 cid_10138259 BD00031095 n/a n/a 150 n/a n/a BindingDB BindingDB
42 CLK2 SU_14813 SU_14813 n/a n/a 150 n/a n/a NB2008 NB2008
43 CLK2 SU_14813 SU_14813 n/a n/a 150 n/a n/a NB2011DRx NB2011DRx
44 CLK2 GSK_1838705A GSK_1838705A n/a n/a 16 n/a n/a NB2011DRx NB2011DRx
45 CLK2 R406 R406 n/a n/a 1600 n/a n/a NB2011DRx NB2011DRx
46 CLK2 CHEMBL522892 BD50265677 n/a n/a 1700 n/a n/a BindingDB BindingDB
47 CLK2 AT_7519 AT_7519 n/a n/a 1700 n/a n/a NB2011DRx NB2011DRx
48 CLK2 CHIR_258 CHIR_258 n/a n/a 1700 n/a n/a NB2008 NB2008
49 CLK2 CHIR_258 CHIR_258 n/a n/a 1700 n/a n/a NB2011DRx NB2011DRx
50 CLK2 SKI_606 SKI_606 n/a n/a 1700 n/a n/a NB2011DRx NB2011DRx
51 CLK2 cid_11409972 BD00031085 n/a n/a 1800 n/a n/a BindingDB BindingDB
52 CLK2 AST_487 AST_487 n/a n/a 1800 n/a n/a NB2008 NB2008
53 CLK2 AST_487 AST_487 n/a n/a 1800 n/a n/a NB2011DRx NB2011DRx
54 CLK2 EKB_569 EKB_569 n/a n/a 1800 n/a n/a NB2008 NB2008
55 CLK2 MLN-518 BD00013535 n/a n/a 1900 n/a n/a BindingDB BindingDB
56 CLK2 SU11248 BD00004814 n/a n/a 20 n/a n/a BindingDB BindingDB
57 CLK2 Sunitinib Sunitinib n/a n/a 20 n/a n/a NB2008 NB2008
58 CLK2 Sunitinib Sunitinib n/a n/a 20 n/a n/a NB2011DRx NB2011DRx
59 CLK2 Flavopiridol Flavopiridol n/a n/a 2200 n/a n/a NB2008 NB2008
60 CLK2 Flavopiridol Flavopiridol n/a n/a 2200 n/a n/a NB2011DRx NB2011DRx
61 CLK2 MLN_120B MLN_120B n/a n/a 2300 n/a n/a NB2011DRx NB2011DRx
62 CLK2 TG_101348 TG_101348 n/a n/a 2300 n/a n/a NB2011DRx NB2011DRx
63 CLK2 PLX_4720 PLX_4720 n/a n/a 2600 n/a n/a NB2011DRx NB2011DRx
64 CLK2 JNJ-7706621 BD00006866 n/a n/a 290 n/a n/a BindingDB BindingDB
65 CLK2 JNJ_7706621 JNJ_7706621 n/a n/a 290 n/a n/a NB2008 NB2008
66 CLK2 SP600125 BD00016018 n/a n/a 300 n/a n/a BindingDB BindingDB
67 CLK2 cid_11712649 BD00031093 n/a n/a 3200 n/a n/a BindingDB BindingDB
68 CLK2 MLN_8054 MLN_8054 n/a n/a 3200 n/a n/a NB2008 NB2008
69 CLK2 MLN_8054 MLN_8054 n/a n/a 3200 n/a n/a NB2011DRx NB2011DRx
70 CLK2 PHA_665752 PHA_665752 n/a n/a 410 n/a n/a NB2011DRx NB2011DRx
71 CLK2 LY333531 BD00017055 n/a n/a 420 n/a n/a BindingDB BindingDB
72 CLK2 LY_333531 LY_333531 n/a n/a 420 n/a n/a NB2008 NB2008
73 CLK2 LY_333531 LY_333531 n/a n/a 420 n/a n/a NB2011DRx NB2011DRx
74 CLK2 TG_100_115 TG_100_115 n/a n/a 43 n/a n/a NB2011DRx NB2011DRx
75 CLK2 LY_317615 LY_317615 n/a n/a 430 n/a n/a NB2011DRx NB2011DRx
76 CLK2 CHEMBL603469 BD50308060 n/a n/a 44 n/a n/a BindingDB BindingDB
77 CLK2 CEP_701 CEP_701 n/a n/a 44 n/a n/a NB2011DRx NB2011DRx
78 CLK2 BI_2536 BI_2536 n/a n/a 460 n/a n/a NB2011DRx NB2011DRx
79 CLK2 INCB18424 INCB18424 n/a n/a 460 n/a n/a NB2011DRx NB2011DRx
80 CLK2 (R)-Roscovitine BD00007533 n/a n/a 470 n/a n/a BindingDB BindingDB
81 CLK2 PI_103 PI_103 n/a n/a 5500 n/a n/a NB2011DRx NB2011DRx
82 CLK2 GDC_0941 GDC_0941 n/a n/a 600 n/a n/a NB2011DRx NB2011DRx
83 CLK2 MLN_518 MLN_518 n/a n/a 6500 n/a n/a NB2011DRx NB2011DRx
84 CLK2 cid_6445562 BD00031090 n/a n/a 700 n/a n/a BindingDB BindingDB
85 CLK2 CHEBI:259924 BD50119072 n/a n/a 700 n/a n/a BindingDB BindingDB
86 CLK2 Roscovitine Roscovitine n/a n/a 700 n/a n/a NB2008 NB2008
87 CLK2 GSK_690693 GSK_690693 n/a n/a 730 n/a n/a NB2011DRx NB2011DRx
88 CLK2 BIBF_1120der BIBF_1120der n/a n/a 760 n/a n/a NB2011DRx NB2011DRx
89 CLK2 CHEMBL162 BD50059889 n/a n/a 8.2 n/a n/a BindingDB BindingDB
90 CLK2 Staurosporine Staurosporine n/a n/a 8.2 n/a n/a NB2008 NB2008
91 CLK2 Staurosporine Staurosporine n/a n/a 8.2 n/a n/a NB2011DRx NB2011DRx
92 CLK2 R547 R547 n/a n/a 80 n/a n/a NB2011DRx NB2011DRx
93 CLK2 TAE_684 TAE_684 n/a n/a 82 n/a n/a NB2011DRx NB2011DRx
94 CLK2 cid_451705 BD00031096 n/a n/a 8200 n/a n/a BindingDB BindingDB
95 CLK2 CHEBI:668343 BD50298227 n/a n/a 860 n/a n/a BindingDB BindingDB
96 CLK2 CHEMBL608533 BD50326053 n/a n/a 860 n/a n/a BindingDB BindingDB
97 CLK2 PKC_412 PKC_412 n/a n/a 860 n/a n/a NB2008 NB2008
98 CLK2 PKC_412 PKC_412 n/a n/a 860 n/a n/a NB2011DRx NB2011DRx
99 CLK2 KW_2449 KW_2449 n/a n/a 93 n/a n/a NB2011DRx NB2011DRx
100 CLK2 JNJ_28312141 JNJ_28312141 n/a n/a 940 n/a n/a NB2011DRx NB2011DRx
101 CLK2 CHEMBL408982 BD50229953 n/a n/a 95 n/a n/a BindingDB BindingDB
102 CLK2 CAS119139_23_0 CAS119139_23_0 n/a n/a n/a n/a 46.67 NB2011RBC NB2011RBC
103 CLK2 CAS120685_11_2 CAS120685_11_2 n/a n/a n/a n/a 36.04 NB2011RBC NB2011RBC
104 CLK2 CAS133052_90_1 CAS133052_90_1 n/a n/a n/a n/a 28.02 NB2011RBC NB2011RBC
105 CLK2 CAS190654_01_4 CAS190654_01_4 n/a n/a n/a n/a 26.57 NB2011RBC NB2011RBC
106 CLK2 CAS212779_48_1 CAS212779_48_1 n/a n/a n/a n/a 25.01 NB2011RBC NB2011RBC
107 CLK2 CAS212844_53_6 CAS212844_53_6 n/a n/a n/a n/a 21.89 NB2011RBC NB2011RBC
108 CLK2 CAS220792_57_4 CAS220792_57_4 n/a n/a n/a n/a 17.65 NB2011RBC NB2011RBC
109 CLK2 CAS257879_35_9 CAS257879_35_9 n/a n/a n/a n/a 14.66 NB2011RBC NB2011RBC
110 CLK2 CAS300801_52_9 CAS300801_52_9 n/a n/a n/a n/a 25.9 NB2011RBC NB2011RBC
111 CLK2 CAS326914_10_7 CAS326914_10_7 n/a n/a n/a n/a 15.77 NB2011RBC NB2011RBC
112 CLK2 CAS330161_87_0 CAS330161_87_0 n/a n/a n/a n/a 32.09 NB2011RBC NB2011RBC
113 CLK2 CAS345987_15_7 CAS345987_15_7 n/a n/a n/a n/a 48.55 NB2011RBC NB2011RBC
114 CLK2 CAS405169_16_6 CAS405169_16_6 n/a n/a n/a n/a 38.61 NB2011RBC NB2011RBC
115 CLK2 CAS443798_55_8 CAS443798_55_8 n/a n/a n/a n/a 3.81 NB2011RBC NB2011RBC
116 CLK2 CAS444723_13_1 CAS444723_13_1 n/a n/a n/a n/a 40.64 NB2011RBC NB2011RBC
117 CLK2 CAS557795_19_4 CAS557795_19_4 n/a n/a n/a n/a 13.59 NB2011RBC NB2011RBC
118 CLK2 CAS608512_97_6 CAS608512_97_6 n/a n/a n/a n/a 9.96 NB2011RBC NB2011RBC
119 CLK2 CAS622387_85_3 CAS622387_85_3 n/a n/a n/a n/a 38.13 NB2011RBC NB2011RBC
120 CLK2 CAS62996_74_1 CAS62996_74_1 n/a n/a n/a n/a 3.71 NB2011RBC NB2011RBC
121 CLK2 CAS658084_23_2 CAS658084_23_2 n/a n/a n/a n/a 5.1 NB2011RBC NB2011RBC
122 CLK2 CAS784211_09_2 CAS784211_09_2 n/a n/a n/a n/a 44.05 NB2011RBC NB2011RBC
123 CLK2 CAS856436_16_3 CAS856436_16_3 n/a n/a n/a n/a 0.33 NB2011RBC NB2011RBC
124 CLK2 CAS866405_64_3 CAS866405_64_3 n/a n/a n/a n/a 21.34 NB2011RBC NB2011RBC
125 CLK2 CAS97161_97_2 CAS97161_97_2 n/a n/a n/a n/a 4.38 NB2011RBC NB2011RBC
126 CLK2 NR9 NR9 n/a n/a n/a n/a n/a PDB PDB