Summary of query kinase
Query kinase NEK2 (P51955)
Kinase group Other
Number of inhibitors 95
Index Target Inhibitor Inhibitor 2D Ki (nM) IC50 (nM) Kd (nM) EC50 (nM) POC Source Link
0 NEK2 CHEMBL398606 BD50222913 n/a 1040 n/a n/a n/a BindingDB BindingDB
1 NEK2 CHEMBL1614933 BD50339795 n/a 1180 n/a n/a n/a BindingDB BindingDB
2 NEK2 CHEMBL1230337 BD50330577 n/a 1200 n/a n/a n/a BindingDB BindingDB
3 NEK2 CHEMBL1278099 BD50330587 n/a 1200 n/a n/a n/a BindingDB BindingDB
4 NEK2 CHEMBL1802384 BD50347866 n/a 130 n/a n/a n/a BindingDB BindingDB
5 NEK2 CHEMBL1230435 BD50330576 n/a 1300 n/a n/a n/a BindingDB BindingDB
6 NEK2 CHEMBL1278189 BD50330586 n/a 1400 n/a n/a n/a BindingDB BindingDB
7 NEK2 CHEMBL1230011 BD50330591 n/a 1500 n/a n/a n/a BindingDB BindingDB
8 NEK2 CHEMBL1277020 BD50330604 n/a 1600 n/a n/a n/a BindingDB BindingDB
9 NEK2 CHEMBL1277201 BD50330605 n/a 1900 n/a n/a n/a BindingDB BindingDB
10 NEK2 CHEMBL1277200 BD50330607 n/a 1900 n/a n/a n/a BindingDB BindingDB
11 NEK2 CHEMBL1802383 BD50347865 n/a 20 n/a n/a n/a BindingDB BindingDB
12 NEK2 CHEMBL1276848 BD50330575 n/a 200 n/a n/a n/a BindingDB BindingDB
13 NEK2 CHEMBL1689165 BD50339800 n/a 230 n/a n/a n/a BindingDB BindingDB
14 NEK2 benzimidazole thiophene carboxamide, 24 BD00028216 n/a 25 n/a n/a n/a BindingDB BindingDB
15 NEK2 CHEMBL1689169 BD50339804 n/a 2560 n/a n/a n/a BindingDB BindingDB
16 NEK2 CHEMBL1277922 BD50330592 n/a 2700 n/a n/a n/a BindingDB BindingDB
17 NEK2 CHEMBL1090360 BD50315888 n/a 310 n/a n/a n/a BindingDB BindingDB
18 NEK2 CHEMBL1288582 BD50331277 n/a 3220 n/a n/a n/a BindingDB BindingDB
19 NEK2 CHEMBL1277021 BD50330580 n/a 3400 n/a n/a n/a BindingDB BindingDB
20 NEK2 CHEMBL1276934 BD50330583 n/a 3400 n/a n/a n/a BindingDB BindingDB
21 NEK2 CHEMBL1615277 BD50339801 n/a 360 n/a n/a n/a BindingDB BindingDB
22 NEK2 CHEMBL1689168 BD50339803 n/a 380 n/a n/a n/a BindingDB BindingDB
23 NEK2 CHEMBL1277755 BD50330595 n/a 390 n/a n/a n/a BindingDB BindingDB
24 NEK2 CHEMBL1802869 BD50347870 n/a 390 n/a n/a n/a BindingDB BindingDB
25 NEK2 CHEMBL1231522 BD50330578 n/a 410 n/a n/a n/a BindingDB BindingDB
26 NEK2 CHEMBL1236707 BD50330606 n/a 4200 n/a n/a n/a BindingDB BindingDB
27 NEK2 CHEMBL1276936 BD50330581 n/a 4300 n/a n/a n/a BindingDB BindingDB
28 NEK2 CHEMBL1689166 BD50339802 n/a 4860 n/a n/a n/a BindingDB BindingDB
29 NEK2 CHEMBL1802385 BD50347867 n/a 4900 n/a n/a n/a BindingDB BindingDB
30 NEK2 CHEMBL1276847 BD50330584 n/a 5400 n/a n/a n/a BindingDB BindingDB
31 NEK2 CHEMBL1689159 BD50339793 n/a 5430 n/a n/a n/a BindingDB BindingDB
32 NEK2 CHEMBL1277475 BD50330598 n/a 5700 n/a n/a n/a BindingDB BindingDB
33 NEK2 CHEMBL1278190 BD50330585 n/a 5900 n/a n/a n/a BindingDB BindingDB
34 NEK2 CHEMBL1802382 BD50347864 n/a 60 n/a n/a n/a BindingDB BindingDB
35 NEK2 CHEMBL1802388 BD50347869 n/a 620 n/a n/a n/a BindingDB BindingDB
36 NEK2 CHEMBL1689160 BD50339794 n/a 6570 n/a n/a n/a BindingDB BindingDB
37 NEK2 CHEMBL1689164 BD50339799 n/a 660 n/a n/a n/a BindingDB BindingDB
38 NEK2 CHEMBL1236145 BD50330579 n/a 710 n/a n/a n/a BindingDB BindingDB
39 NEK2 CHEMBL1277019 BD50330574 n/a 720 n/a n/a n/a BindingDB BindingDB
40 NEK2 CHEMBL1276935 BD50330582 n/a 7200 n/a n/a n/a BindingDB BindingDB
41 NEK2 CHEMBL1802870 BD50347863 n/a 770 n/a n/a n/a BindingDB BindingDB
42 NEK2 CHEMBL1277296 BD50330602 n/a 7800 n/a n/a n/a BindingDB BindingDB
43 NEK2 CHEMBL1802387 BD50347868 n/a 920 n/a n/a n/a BindingDB BindingDB
44 NEK2 PD_173955 PD_173955 n/a n/a 110 n/a n/a NB2011DRx NB2011DRx
45 NEK2 cid_10138259 BD00031095 n/a n/a 1100 n/a n/a BindingDB BindingDB
46 NEK2 SU_14813 SU_14813 n/a n/a 1100 n/a n/a NB2008 NB2008
47 NEK2 SU_14813 SU_14813 n/a n/a 1100 n/a n/a NB2011DRx NB2011DRx
48 NEK2 cid_6445562 BD00031090 n/a n/a 140 n/a n/a BindingDB BindingDB
49 NEK2 CHEBI:259924 BD50119072 n/a n/a 140 n/a n/a BindingDB BindingDB
50 NEK2 Sunitinib Sunitinib n/a n/a 1400 n/a n/a NB2008 NB2008
51 NEK2 Sunitinib Sunitinib n/a n/a 1400 n/a n/a NB2011DRx NB2011DRx
52 NEK2 SKI_606 SKI_606 n/a n/a 1600 n/a n/a NB2011DRx NB2011DRx
53 NEK2 TG_101348 TG_101348 n/a n/a 1700 n/a n/a NB2011DRx NB2011DRx
54 NEK2 TAE_684 TAE_684 n/a n/a 1800 n/a n/a NB2011DRx NB2011DRx
55 NEK2 CHEMBL522892 BD50265677 n/a n/a 2000 n/a n/a BindingDB BindingDB
56 NEK2 BI_2536 BI_2536 n/a n/a 2000 n/a n/a NB2011DRx NB2011DRx
57 NEK2 CHIR_258 CHIR_258 n/a n/a 2000 n/a n/a NB2008 NB2008
58 NEK2 CHIR_258 CHIR_258 n/a n/a 2000 n/a n/a NB2011DRx NB2011DRx
59 NEK2 HKI_272 HKI_272 n/a n/a 250 n/a n/a NB2011DRx NB2011DRx
60 NEK2 GSK_461364A GSK_461364A n/a n/a 260 n/a n/a NB2011DRx NB2011DRx
61 NEK2 R406 R406 n/a n/a 260 n/a n/a NB2011DRx NB2011DRx
62 NEK2 CHEMBL516312 BD50273541 n/a n/a 483 n/a n/a BindingDB BindingDB
63 NEK2 CEP_701 CEP_701 n/a n/a 4900 n/a n/a NB2011DRx NB2011DRx
64 NEK2 SU11248 BD00004814 n/a n/a 500 n/a n/a BindingDB BindingDB
65 NEK2 PLX_4720 PLX_4720 n/a n/a 5000 n/a n/a NB2011DRx NB2011DRx
66 NEK2 KW_2449 KW_2449 n/a n/a 5300 n/a n/a NB2011DRx NB2011DRx
67 NEK2 PHA_665752 PHA_665752 n/a n/a 600 n/a n/a NB2011DRx NB2011DRx
68 NEK2 Dasatinib Dasatinib n/a n/a 6500 n/a n/a NB2011DRx NB2011DRx
69 NEK2 EKB_569 EKB_569 n/a n/a 680 n/a n/a NB2008 NB2008
70 NEK2 Staurosporine BD00002579 n/a n/a 740 n/a n/a BindingDB BindingDB
71 NEK2 CHEMBL162 BD50059889 n/a n/a 740 n/a n/a BindingDB BindingDB
72 NEK2 Staurosporine Staurosporine n/a n/a 750 n/a n/a NB2008 NB2008
73 NEK2 Staurosporine Staurosporine n/a n/a 750 n/a n/a NB2011DRx NB2011DRx
74 NEK2 Pazopanib BD00026474 n/a n/a 980 n/a n/a BindingDB BindingDB
75 NEK2 GW_786034 GW_786034 n/a n/a 980 n/a n/a NB2008 NB2008
76 NEK2 Pazopanib Pazopanib n/a n/a 980 n/a n/a NB2011DRx NB2011DRx
77 NEK2 30E 30E n/a n/a n/a n/a n/a PDB PDB
78 NEK2 430 430 n/a n/a n/a n/a n/a PDB PDB
79 NEK2 4VQ 4VQ n/a n/a n/a n/a n/a PDB PDB
80 NEK2 5R1 5R1 n/a n/a n/a n/a n/a PDB PDB
81 NEK2 5Z5 5Z5 n/a n/a n/a n/a n/a PDB PDB
82 NEK2 ADP ADP n/a n/a n/a n/a n/a PDB PDB
83 NEK2 BX1 BX1 n/a n/a n/a n/a n/a PDB PDB
84 NEK2 CAS380843_75_4 CAS380843_75_4 n/a n/a n/a n/a 8.56 NB2011RBC NB2011RBC
85 NEK2 ED8 ED8 n/a n/a n/a n/a n/a PDB PDB
86 NEK2 EQH EQH n/a n/a n/a n/a n/a PDB PDB
87 NEK2 OL2 OL2 n/a n/a n/a n/a n/a PDB PDB
88 NEK2 SAP SAP n/a n/a n/a n/a n/a PDB PDB
89 NEK2 T3M T3M n/a n/a n/a n/a n/a PDB PDB
90 NEK2 VGK VGK n/a n/a n/a n/a n/a PDB PDB
91 NEK2 WCX WCX n/a n/a n/a n/a n/a PDB PDB
92 NEK2 WGZ WGZ n/a n/a n/a n/a n/a PDB PDB
93 NEK2 WI2 WI2 n/a n/a n/a n/a n/a PDB PDB
94 NEK2 XK3 XK3 n/a n/a n/a n/a n/a PDB PDB