Protein Surface  Ribbon
Inhibitor EQH
  ATP Location
Motifs All P-loop B3 Hinge
C-loop A-loop
Select Anchor
Summary of 2 kinases in KIF 2XK6A_EQH (NEK2, PDB code: 2XK6, chain A)

Multiple sequence alignment of family kinases

Conserved residues:   
                            
Group      Kinase           
Other      NEK2         203 
Other      PLK1          53 



--YEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVS-EVNLLRELKHPNIVRYYDRIIDRTNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNVKLGDFGLARILNHDTSFAKTFVGTPYYMSPEQMNRMSYNEKSDIWSLGCLLYELCALMPPFTAFSQKELAGKIREGKFRRIPYRYSDELNEIITRMLNLKDYHRPSVEEILENPL-I
YV--RGRFLGKGGFAKCFEISDADTKEVFAGKIVPKSLLLKPHQREKMSMEISIHRSLAHQHVVGFHGFFED--NDFVFVVLELCRRRSLLELHK----RRKALTEPEARYYLRQIVLGCQYLHRN-----RVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGKPPFETSCLKETYLRIKKNEYSIPKHIN-PVAASLIQKMLQTDPTARPTINELLNDEFF-