Kinase profiling results of kinases in KIF 2G2IA_ADP (ABL1, PDB code: 2G2I, chain A)
Template Kinase: ABL1
Template inhibitor: Adenosine-5'-diphosphate

 29 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
PDPK1AGC
RPS6KA1AGC
RPS6KA1CAMK
DAPK1CAMK
CDK2CMGC
AURKAOther
NEK2Other
PLK4Other
OXSR1STE
STK24STE
MAP2K1STE
ABL1TK
TNK2TK
ALKTK
EGFRTK
ERBB3TK
EPHA3TK
PTK2BTK
FGFR1TK
FGFR2TK
IGF1RTK
INSRTK
METTK
KITTK
RETTK
SRCTK
HCKTK
LCKTK
ZAP70TK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
PDPK1AGC
RPS6KA1AGC
DAPK1CAMK
CDK2CMGC
AURKAOther
NEK2Other
MAP2K1STE
OXSR1STE
STK24STE
ABL1TK
ALKTK
EGFRTK
EPHA3TK
FGFR1TK
FGFR2TK
HCKTK
IGF1RTK
INSRTK
KITTK
LCKTK
METTK
PTK2BTK
RETTK
SRCTK
TNK2TK
ZAP70TK
IRAK4TKL