Kinase profiling results of kinases in KIF 1O6LA_ANP (AKT2, PDB code: 1O6L, chain A)
Template Kinase: AKT2
Template inhibitor: Phosphoaminophosphonic Acid-Adenylate Ester

11 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
ROCK1AGC
PDPK1AGC
PRKCIAGC
MAPKAPK23
CHEK2CAMK
CDK2CMGC
NEK2Other
RETTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT2AGC
GRK6AGC
PDPK1AGC
PRKCIAGC
ROCK1AGC
CHEK2CAMK
MAPKAPK2CAMK
PASKCAMK
CDK2CMGC
NEK2Other
RETTK