Kinase profiling results of kinases in KIF 1G5SA_I17 (CDK2, PDB code: 1G5S, chain A)
Template Kinase: CDK2
Template inhibitor: H724

 43 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C
ROCK1AGC  
ROCK2AGC  
PRKCDAGC  
PRKCQAGC  
RPS6KA2AGC  
RPS6KA2CAMK  
CAMK2BCAMK  
CHEK1CAMK  
PIM1CAMK  
PIM3CAMK  
CDK2CMGC  
CDK3CMGC  
CDK4CMGC  
CDK5CMGC  
CDK9CMGC  
CSNK2A1CMGC  
CLK2CMGC  
CLK4CMGC  
GSK3BCMGC  
MAPK8CMGC  
MAPK9CMGC  
MAPK14CMGC  
AURKAOther  
AURKBOther  
CHUKOther  
EIF2AK2Other  
PLK1Other  
SLKSTE  
ABL1TK  
FGFR1TK  
JAK2TK  
JAK3TK  
METTK  
FGRTK  
FYNTK  
SRCTK  
YES1TK  
LCKTK  
ZAP70TK  
ITKTK  
NTRK3TK  
IRAK4TKL  

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
PRKCAAGC   
PRKCDAGC   
PRKCQAGC   
ROCK1AGC   
ROCK2AGC   
RPS6KA2AGC   
CAMK2BCAMK   
CHEK1CAMK   
PIM1CAMK   
PIM3CAMK   
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
CDK3CMGC   
CDK4CMGC   
CDK5CMGC   
CDK9CMGC   
CLK2CMGC   
CLK4CMGC   
CSNK2A1CMGC   
GSK3BCMGC   
MAPK14CMGC   
MAPK8CMGC   
MAPK9CMGC   
AURKAOther   
AURKBOther   
CHUKOther   
PLK1Other   
SLKSTE   
ABL1TK   
FGFR1TK   
FGRTK   
FYNTK   
ITKTK   
JAK2TK   
JAK3TK   
LCKTK   
METTK   
NTRK3TK   
SRCTK   
YES1TK   
ZAP70TK   
IRAK4TKL