Kinase profiling results of kinases in KIF 1HCKA_ATP (CDK2, PDB code: 1HCK, chain A)
Template Kinase: CDK2
Template inhibitor: Adenosine-5'-triphosphate

 38 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
AKT2AGC
ROCK1AGC
PDPK1AGC
PRKCIAGC
CASKCAMK
DAPK1CAMK
PIM1CAMK
CHEK2CAMK
CDK2CMGC
CDK7CMGC
CDK9CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
ERN1Other
NEK2Other
NEK7Other
EIF2AK2Other
PLK1Other
TTKOther
OXSR1STE
STK24STE
MAP2K1STE
MAP2K4STE
ABL1TK
TNK2TK
PTK2TK
FGFR2TK
METTK
MST1RTK
SRCTK
HCKTK
LCKTK
ZAP70TK
IRAK4TKL

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
AKT2AGC
GRK6AGC
PDPK1AGC
PRKCIAGC
ROCK1AGC
CHEK2CAMK
DAPK1CAMK
PIM1CAMK
CDK2CMGC
CDK7CMGC
CDK9CMGC
CSNK2A1CMGC
GSK3BCMGC
MAPK10CMGC
MAPK12CMGC
AURKAOther
NEK2Other
NEK7Other
PLK1Other
TTKOther
MAP2K1STE
OXSR1STE
STK24STE
ABL1TK
FGFR2TK
HCKTK
LCKTK
METTK
MST1RTK
PTK2TK
SRCTK
TNK2TK
ZAP70TK
IRAK4TKL