Kinase profiling results of kinases in KIF 1JVPP_LIG (CDK2, PDB code: 1JVP, chain P)
Template Kinase: CDK2
Template inhibitor: ellipticine

17 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group
ROCK2AGC
PRKACAAGC
CHEK1CAMK
PIM1CAMK
CHEK2CAMK
CDK2CMGC
CDK5CMGC
GSK3BCMGC
MAPK10CMGC
MAPK8CMGC
MAPK9CMGC
MAPK14CMGC
AURKAOther
AURKBOther
JAK2TK
METTK
ITKTK

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C C
PRKACAAGC    
ROCK2AGC    
CHEK1CAMK    
CHEK2CAMK    
PIM1CAMK    
CDK2CMGC    
CDK5CMGC    
GSK3BCMGC    
MAPK10CMGC    
MAPK14CMGC    
MAPK8CMGC    
MAPK9CMGC    
AURKAOther    
AURKBOther    
ITKTK    
JAK2TK    
METTK