Kinase profiling results of kinases in KIF 1PYEA_PM1 (CDK2, PDB code: 1PYE, chain A)
Template Kinase: CDK2
Template inhibitor: AC1NRCTO

 10 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C
CDK2CMGC 
CDK4CMGC 
CLK4CMGC 
MAPK14CMGC 
FGFR1TK 
JAK1TK 
JAK2TK 
JAK3TK 
SRCTK 

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group
CDC2CMGC
CDC2CMGC
CDK2CMGC
CDK4CMGC
CLK4CMGC
MAPK14CMGC
FGFR1TK
JAK1TK
JAK2TK
JAK3TK
SRCTK