Kinase profiling results of kinases in KIF 2B55A_D31 (CDK2, PDB code: 2B55, chain A)
Template Kinase: CDK2
Template inhibitor: D31

 27 kinases in the family
Kinase profiling results source
1. Davis et al. Nature Biotechnology.29, 1046-51
2. Anastassiadis, T. et al. Nature Biotechnology.29, 1039-45


Similarity between template inhibitor and test compounds of profiling results

Davis et al.
Nature Biotechnology.29, 1046-51

<1nM    >10uM
KinaseKinase group C C C
AKT1AGC   
AKT2AGC   
AKT3AGC   
ROCK1AGC   
ROCK2AGC   
PDPK1AGC   
RPS6KA5AGC   
RPS6KA5CAMK   
CHEK1CAMK   
CDK2CMGC   
CDK4CMGC   
CDK5CMGC   
GSK3ACMGC   
GSK3BCMGC   
MAPK14CMGC   
AURKAOther   
AURKBOther   
PLK1Other   
PLK3Other   
ABL1TK   
AXLTK   
FGFR1TK   
JAK2TK   
SRCTK   
LCKTK   
ITKTK   

Anastassiadis, T. et al.
Nature Biotechnology.29, 1039-45

0%    100%
KinaseKinase group C C C
AKT1AGC   
AKT2AGC   
AKT3AGC   
PDPK1AGC   
PRKCAAGC   
ROCK1AGC   
ROCK2AGC   
RPS6KA5AGC   
CHEK1CAMK   
CDC2CMGC   
CDC2CMGC   
CDK2CMGC   
CDK4CMGC   
CDK5CMGC   
GSK3ACMGC   
GSK3BCMGC   
MAPK14CMGC   
AURKAOther   
AURKBOther   
PLK1Other   
PLK3Other   
ABL1TK   
AXLTK   
FGFR1TK   
ITKTK   
JAK2TK   
LCKTK   
SRCTK